ABSTRACT
In April 2012, an outbreak of acute respiratory illness occurred in a public hospital in Zarqa city, in Jordan; 8 health care workers were among the 11 people affected, 1 of who later died. The cause of the outbreak was unknown at the time and an epidemiological investigation including laboratory testing carried out immediately afterthe outbreak was inconclusive. Following the discovery of novel coronavirus infection (nCoV) in the Arabian peninsula in September 2012, stored respiratory and serum samples of patients from this outbreak were retested and the diagnosis of nCoV was confirmed in 2 deceased patients. This paper describes the epidemiological findings of retrospective investigation carried out in November 2012 and highlights the likelihood of nosocomial transmission of nCoV infection in a health-care setting. A total of 2 laboratory-confirmed and 11 probable cases were identified from this outbreak of whom 10 were HCWs and 2 were family members of cases.
Subject(s)
Coronavirus Infections/epidemiology , Disease Outbreaks/statistics & numerical data , Adult , Age Distribution , Aged , Coronavirus Infections/transmission , Cross Infection/epidemiology , Cross Infection/transmission , Female , Health Personnel/statistics & numerical data , Humans , Jordan/epidemiology , Male , Middle Aged , Retrospective Studies , Sex DistributionABSTRACT
In April 2012, an outbreak of acute respiratory illness occurred in a public hospital in Zarqa city, in Jordan; 8 health care workers were among the 11 people affected, 1 of who later died. The cause of the outbreak was unknown at the time and an epidemiological investigation including laboratory testing carried out immediately after the outbreak was inconclusive. Following the discovery of novel coronavirus infection [nCoV] in the Arabian peninsula in September 2012, stored respiratory and serum samples of patients from this outbreak were retested and the diagnosis of nCoV was confirmed in 2 deceased patients. This paper describes the epidemiological findings of retrospective investigation carried out in November 2012 and highlights the likelihood of nosocomial transmission of nCoV infection in a health-care setting. A total of 2 laboratory-confirmed and 11 probable cases were identified from this outbreak of whom 10 were HCWs and 2 were family members of cases
ABSTRACT
One of the most frequent chromosomal translocations in human beings is 11q/22q, which results in the "partial trisomy of 22q syndrome." However, the breakpoint on the long arms of chromosomes 11 and 22 is still a matter of controversy. In the present study, we have used chromosomes from lymphocytes of a neonate who happened to have this classical abnormality, and by R-banding prometaphase chromosomes with acridine orange it has been possible to establish that the translocation between chromosomes 11 and 22 resulted from 3:1 meiotic maternal nondisjunction. A detailed analysis of the chromosome regions involved in this translocation revealed that the breakpoints on chromosomes 11 and 22 were at 11q23.3 and 22q11.1, respectively.
Subject(s)
Chromosomes, Human, 21-22 and Y , Chromosomes, Human, 6-12 and X , Translocation, Genetic , Abnormalities, Multiple/genetics , Chromosome Banding , Female , Humans , Infant, Newborn , Karyotyping , Lymphocytes/cytology , MaleABSTRACT
Skin sloughs and necrosis from hypertonic solutions may occur in premature infants receiving peripheral intravenous fluid therapy. A simple multiple puncture method is proposed to remove the infiltrate and prevent skin sloughs.
