ABSTRACT
No disponible
Subject(s)
Women , Gender Identity , Equity , Scientific and Technical Publications , Pediatrics , Spain/epidemiologyABSTRACT
No disponible
Subject(s)
Humans , Pediatrics/education , Pediatrics/ethics , 51577/methods , 51577/policies , Publishing/ethics , Publishing/instrumentation , Peer Review, Research/ethics , Peer Review, Research/methods , Pediatrics , Pediatrics/methods , 51577/analysis , 51577/classification , Publishing/classification , Publishing , Peer Review, Research/legislation & jurisprudence , Peer Review, Research/trendsABSTRACT
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Subject(s)
Humans , Editorial Policies , Manuscripts as Topic , Periodicals as Topic , MultilingualismABSTRACT
No disponible
Subject(s)
Humans , Editorial Policies , Pediatrics/trends , 34002 , Periodicals as Topic/trendsABSTRACT
Purpura fulminans (PF) is an infrequent complication of varicella characterized by the progressive development of purpuric or painful ecchymotic lesions associated with biochemical alternations typical of consumption coagulopathy. Activation of coagulation is due to a marked and prolonged decrease in protein S, which is probably secondary to the formation of antiprotein S antibodies. The mechanism responsible for the synthesis of these autoantibodies is unknown. We present three cases of postvaricella PF and review the clinical and biochemical characteristics of this entity, as well as current diagnostic and therapeutic recommendations.
Subject(s)
Chickenpox/complications , IgA Vasculitis/etiology , Antibodies , Autoantibodies , Chickenpox/immunology , Child , Child, Preschool , Female , Humans , IgA Vasculitis/diagnosis , Male , Protein S/immunologyABSTRACT
La púrpura fulminante es una complicación rara de la varicela que se caracteriza por la aparición progresiva de lesiones purpúricas o equimóticas dolorosas asociado a una alteración analítica propia de una coagulopatía de consumo. La activación de la coagulación es debida a un descenso marcado y prolongado de la proteína S, que probablemente es secundario a la formación de anticuerpos antiproteína S. El mecanismo responsable de la síntesis de estos autoanticuerpos es desconocido. Se presentan 3 casos de púrpura fulminante posvaricelosa y se revisan las características clinicoanalíticas y las recomendaciones diagnosticoterapéuticas actuales de esta entidad (AU)
