ABSTRACT
Calculated results are presented for the frequency with which various partial nuclear reaction cross sections are utilized when fast neutrons (approximately less than 50 MeV) are transported through a tissue-equivalent phantom to obtain an indication of which cross sections are of most importance for radiotherapy applications and are therefore in need of experimental verification.
Subject(s)
Fast Neutrons , Neutrons , Radiotherapy, High-Energy , Technology, Radiologic , Models, StructuralSubject(s)
Elementary Particles/therapeutic use , Radiotherapy , Aerobiosis , Alpha Particles/therapeutic use , Cell Hypoxia , Cell Line/radiation effects , Cell Survival , Dose-Response Relationship, Radiation , Kidney/cytology , Kidney/radiation effects , Linear Energy Transfer , Mesons/therapeutic use , Models, Biological , Neutrons/therapeutic use , Oxygen/pharmacology , Photons/therapeutic use , Proton Therapy , Relative Biological EffectivenessSubject(s)
Bone and Bones , Elementary Particles , Neoplasms/radiotherapy , Radiotherapy Dosage , Cell Survival , Kidney , Models, Structural , Monte Carlo Method , OxygenSubject(s)
Fast Neutrons , Neutrons , Thermoluminescent Dosimetry/instrumentation , Cadmium , Fluorides , LithiumABSTRACT
The designing of radiation shields for manned space vehicles and for high-energy accelerators requires a knowledge of the nucleon-meson cascade that develops when a high-energy particle enters matter. The accuracy with which calculations of the nucleon-meson cascade can be made is to a large extent determined by the available information on particle production from nuclear reactions. The accuracy with which an effective shield can be designed is also determined by the available information on the biological effects of radiation.