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1.
Results Phys ; 38: 105613, 2022 Jul.
Article in English | MEDLINE | ID: mdl-35600673

ABSTRACT

Since the previous two years, a new coronavirus (COVID-19) has found a major global problem. The speedy pathogen over the globe was followed by a shockingly large number of afflicted people and a gradual increase in the number of deaths. If the survival analysis of active individuals can be predicted, it will help to contain the epidemic significantly in any area. In medical diagnosis, prognosis and survival analysis, neural networks have been found to be as successful as general nonlinear models. In this study, a real application has been developed for estimating the COVID-19 mortality rates in Italy by using two different methods, artificial neural network modeling and maximum likelihood estimation. The predictions obtained from the multilayer artificial neural network model developed with 9 neurons in the hidden layer were compared with the numerical results. The maximum deviation calculated for the artificial neural network model was -0.14% and the R value was 0.99836. The study findings confirmed that the two different statistical models that were developed had high reliability.

2.
Sci Rep ; 11(1): 12865, 2021 06 18.
Article in English | MEDLINE | ID: mdl-34145347

ABSTRACT

In this investigation, heat transportation together with irreversibility analysis for the flow of couple stress hybrid nanofluid past over a stretching surface is considered. The innovative characteristics and aims of this work are to note that the transportation heat couple stress model involves EMHD, viscous dissipation, Joule heating, and heat absorption, and omission. The hybrid nanofluid is prepared due to the suspension of the solid nanoparticles of the SWCNTs and MWCNTs in pure human blood. This mathematical model is an appropriate model for biological advantages including testing of human blood for drug deliveries to various parts of the human body. Particularly, the Prandtl number used for the blood is 21 and very large as compared to the other base fluids. Necessary modifications are used to translate the defining partial differential equations and boundary conditions into a layout that can be computed. To obtain mathematical approximations for the resulting scheme of nonlinear differential equations, the innovative homotopy analysis method (HAM) is used. The explanation for velocity, energy, and entropy are exposed and the flow against various influential factors ([Formula: see text]) is discussed graphically. The numerical values are calculated and summarized for dimensionless [Formula: see text] In addition, the current study is compared for various values of [Formula: see text] to that published literature and an impressive agreement in terms of finding is reported. It has also been noticed that the [Formula: see text] and [Formula: see text] factors retard the hybrid nanofluid flow, while the temperature of fluid becomes upsurges by the rise in these factors. 11.95% enhancement in the heat transfer rate has been attained using the hybrid nanofluids.


Subject(s)
Electromagnetic Fields , Hydrodynamics , Models, Theoretical , Stress, Mechanical , Algorithms , Humans , Solutions , Temperature
3.
Sci Rep ; 11(1): 11621, 2021 06 02.
Article in English | MEDLINE | ID: mdl-34079026

ABSTRACT

The current study focuses on the laminar flow of copper and copper oxide ([Formula: see text] and [Formula: see text]) hybrid nanoliquid, considering blood as a carrier fluid in a rectangular domain between two permeable channels. This study may manipulate for the purpose such as the drug delivery process, flow dynamic mechanism of the micro-circulatory system. In the proposed model, MHD and heat source/sink on the flow pattern have been studied. Furthermore, the sides of each channel are permeable, allowing the nanoliquid to escape, filter, squeezing and dilating with a fixed velocity. Appropriate transformations are incorporated to convert the governing partial differential equations and the boundary conditions suitable for computation. The elegant homotopy analysis method (HAM) is used to obtain analytic approximations for the resulting system of nonlinear differential equations. The features of flow characteristics such as velocity, and temperature profiles in response to the variations of the emerging parameters are simulated and examined with a physical explanation. The magnetic field plays a vital role in the blood flow and therefore the existing literature has been extending with the addition of magnetic field. Among the many outputs of the study, it is found that the pressure distribution decline with the accumulated values of the magnetic parameter at the center of the flow regime. The augmentation in the temperature distribution estimates the pH values and electric conductivity. Therefore, the [Formula: see text] hybrid nanofluids are used in this study for medication purposes. The magnetic field has an important role in the blood flow and therefore the extending study has been extending using the magnetic field. The heat emission/absorption term is added to the energy equation to maintain the homogeneous temperature for the blood flow. We expect that this work will provide efficient outputs for medical purposes such as drug delivery.

4.
Biom J ; 57(1): 27-38, 2015 Jan.
Article in English | MEDLINE | ID: mdl-24838310

ABSTRACT

Risk assessment studies where human, animal or ecological data are used to set safe low dose levels of a toxic agent are challenging as study information is limited to high dose levels of the agent. Simultaneous hyperbolic confidence bands for low-dose risk estimation with quantal data have been proposed in the literature. In this paper, a new method using three-segment confidence bands to construct simultaneous upper confidence limits on extra risks and simultaneous lower bounds on the benchmark dose for quantal data is proposed. The proposed method is illustrated with a real data application and simulation studies.


Subject(s)
Biostatistics/methods , Toxicology , Uncertainty , Animals , Benchmarking , Confidence Intervals , Dose-Response Relationship, Drug , Humans , Risk Assessment , Time Factors
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