ABSTRACT
We recently saw a patient with endomyocardial fibrosis of the left ventricle, with aortic, mitra, and tricuspid valve involvement. The patient resided in Madrid and had never been to Africa. There was no history of filariasis. The patient underwent left ventricle endocardiectomy, aortic and mitral valve replacement with tricuspid valve commissurotomy, and Carpentier annuloplasty. Prospective follow-up was uneventful. Pathogenesis and surgical features are discussed herein.
Subject(s)
Aortic Valve/surgery , Endomyocardial Fibrosis/surgery , Mitral Valve/surgery , Tricuspid Valve/surgery , Adult , Aortic Valve/pathology , Endomyocardial Fibrosis/pathology , Female , Heart Valve Diseases/pathology , Heart Valve Diseases/surgery , Humans , Mitral Valve/pathology , Tricuspid Valve/pathologyABSTRACT
The cerebral cortex of a patient with Schilder's disease was studied with the Golgi method. The number of synaptic spines, basal dendrites, branching points, and dendritic intersection points of 5th layer pyramids are similar to those of controls, in spite of almost complete loss of extrinsic fibers. These data illustrate the probable remodeling of intrinsic cortical circuits and neuronal plasticity in the human cerebral cortex.