ABSTRACT
El Síndrome de Ramsay Hunt es una entidad infrecuente, con una incidencia de 5 por cada 100.000 personas por año. Esta condición se caracteriza por una reactivación del virus de la varicela-zoster en el nervio facial. Su diagnóstico implica un reto para el médico puesto que suele ser netamente clínico, con la aparición de una triada consistente en: otalgia, parálisis facial ipsilateral y vesículas en el canal auditivo. El objetivo del artículo es presentar el caso de una mujer de 49 años de edad, con antecedente de epilepsia en tratamiento anticonvulsivante, quien ingresa con la triada clínica antes descrita, asociada a visión borrosa derecha y vértigo. La paciente fue tratada con antivirales y corticoides orales, presentando una resolución clínica favorable dado una reducción de más del 50% de las lesiones cutáneas. No se identificaron diferencias respecto a la presentación clínica de este síndrome al compararse con pacientes no epilépticos.
Ramsay Hunt Syndrome is a rare entity, with an incidence of 5 per 100,000 people per year. This condition is characterized by a reactivation of the varicella-zoster virus in the facial nerve. Its diagnosis implies a challenge for the physician since it is usually a clinical diagnosis, with the appearance of a clinical triad consisting of: otalgia, ipsilateral facial paralysis and vesicles in the ear canal. The objective of the article is to present the case of a 49-year-old woman, with a history of epilepsy receiving anticonvulsant treatment, who was admitted with the aforementioned clinical triad, associated with blurred right vision and vertigo. The patient was treated with oral antiviral management and oral corticosteroids, presenting a favorable clinical resolution given a reduction of more than 50% of the skin lesions. No differences were identified regarding the clinical presentation of this syndrome when compared with non-epileptic patients.
Subject(s)
Humans , Female , Middle Aged , Herpes Zoster Oticus , Facial Paralysis , Varicella Zoster Virus Infection , Herpesvirus 3, Human , Epilepsy , Herpes ZosterABSTRACT
The trophic relationships of pelagic fishes with migratory traits such as the South Pacific Bonito, Sarda chiliensis chiliensis (Cuvier, 1832), have not been studied in depth in the past. The objective of the present research was to analyze the feeding habits of South Pacific Bonito by sex and to analyze a comparison between summer and autumn months in three different areas of the eastern South Pacific by applying different techniques used in trophic biology. Between December 2013 and June 2014, specimens were captured in the areas of Pozo de Lisas (Ilo, Peru), La Capilla (Arica, Chile) and Chanavayita (Iquique, Chile). The feeding dynamics and trophic composition of the diet were analyzed, as well as the feeding strategy and trophic relationships. A total of 1404 specimens were analyzed, of which 654 had stomach contents. Seven prey items were identified: (a) fish remains; (b) squid jaw remains; (c) squid gladius remains; (d) caudal fin remains; (e) Engraulis rigens; (f) Pleuroncodes monodon and (g) N/A (not determined). The Pozo de Lisas and La Capilla areas showed homogeneity in their prey items, while the Chanavayita area showed more diversity. Regarding the importance of prey items in the diet of S. chiliensis in the three localities, it would be correct to state that it is a generalist species.
ABSTRACT
Introduction: Adverse drug reactions (ADR) are a problem for healthcare systems worldwide. Pediatric patients constitute a vulnerable group with regard to ADRs. However, although pediatric patients are at increased risk for these reactions, there is little progress on ADR detection methods in this group.Areas covered: In this systematic search, performed according to PRISMA statements, we selected studies, published in PubMed/Medline databases; Scopus; LILACS; Web of Science; Embase and Cochrane Library until April, 2020, on ADRs in hospitalized pediatric patients.Expert opinion: The increase of pediatric drug safety data is essential to the improvement of childcare. Health services must continuously stimulate educational programs focused on ADR detection tools to minimize the barriers and raise awareness among professionals. Therefore, it is necessary to consider that each method has advantages and disadvantages and must be analyzed in detail to be implemented according to the peculiarities of each practice scenario. Triggers tools (active method) correlated with electronic medical notes seems a good strategy for ADR identification, whether pediatric parameters are well checked and adapted with each age group. In any event, combined methods will add data to identification and clearer ADR assessment.
Subject(s)
Adverse Drug Reaction Reporting Systems , Drug-Related Side Effects and Adverse Reactions/epidemiology , Pharmacovigilance , Age Factors , Child , Drug-Related Side Effects and Adverse Reactions/diagnosis , Electronic Health Records/statistics & numerical data , Humans , Vulnerable PopulationsABSTRACT
Verst-Maldaun Language Assessment (VMLA) is a new intraoperative neuropsychological test (NT) within our local culture, e.g., native Portuguese speaking Brazilians. It aims to fill the specific need of an objective and dynamic approach for assessing the language network during awake craniotomies. The test includes object naming (ON) and semantic functions. This paper describes the process of validation, allowing for other centers to create their own language assessment. The validation process included 248 volunteers and the results were associated with age, gender and educational level (EL). The factor with the greatest impact was EL, followed by age. Intraoperative image learning by repetition is unlikely, since it is composed of 388 items and 70 combinations. The test will be available for free use under http://www.vemotests.com/ (beginning in February 2021).
Subject(s)
Craniotomy , Intraoperative Neurophysiological Monitoring/methods , Language Tests , Wakefulness , Adolescent , Adult , Aged , Aged, 80 and over , Brazil , Child , Educational Status , Female , Humans , Male , Middle Aged , Neuropsychological Tests , Reference Values , Reproducibility of Results , Semantics , Young AdultABSTRACT
Resumen En este artículo se presentan las narrativas emergentes en torno al conflicto armado y la reconciliación social, resultantes de un proceso de diálogo entre distintos actores sociales, incluidas víctimas y excombatientes, llevado a cabo en Samaná (Caldas). El diseño metodológico utilizó la herramienta de Diálogo Público para cumplir simultáneamente propósitos de investigación y acción, y el análisis del discurso para identificar las posiciones discursivas de los participantes frente al conflicto y sus actores, y comprender los movimientos que los enunciados evidencian a partir de la experiencia en el diálogo. Los hallazgos revelan una narrativa de polarización en la que predominan los estereotipos al comienzo del diálogo y una transformación hacia una narrativa de reconocimiento del otro, lo que permite concluir que el diálogo, como práctica colectiva, promueve la reconciliación social.
Abstract This article presents emerging narratives around armed conflict and social reconciliation, resulting from a process of dialogue among different social actors, by including victims and ex-combatants, carried out, in Samaná, Caldas. The methodological design used the Public Dialogue tool to simultaneously fulfill research and action purposes and discourse analysis in order to identify the discursive positions of participants regarding conflict and their actors, and to understand the movements that statements demonstrate from experience in dialogue. The findings reveal a polariza tion narrative in which stereotypes predominate at the beginning of dialogue and a transformation towards a narrative of recognition of the other, which makes it possible to conclude that dialogue, as a collective practice, promotes social reconciliation.
ABSTRACT
AIM: To evaluate the inflammatory response, biomineralization and production of osteocalcin (OCN), osteopontin (OPN), and bone sialoprotein (BSP) of a new root filling material for primary teeth (Bio-C Pulpecto) compared to MTA. DESIGN: Polyethylene tubes containing Bio-C Pulpecto, MTA, and empty tubes were implanted into the dorsal connective tissue. After 7, 15, 30, 60, and 90 days, the tubes with surrounding tissue were removed and histologically processed to be analysed using haematoxylin and eosin, von Kossa staining, or no staining for observation under polarized light and immunohistochemistry for the detection of OCN, OPN, and BSP. The Kruskal-Wallis test was used followed by Dunn's test. The significance level was set at 5%. RESULTS: The inflammatory response observed with MTA and Bio-C Pulpecto was more exacerbated until the 15th day and decreased from 30 days on. No significant difference was found between control, MTA, and Bio-C Pulpecto (P > 0.05). Bio-C Pulpecto and MTA showed positivity for von Kossa and birefringent to polarized light. The immunolabelling for OCN, OPN, and BSP was more intense for MTA and Bio-C Pulpecto on days 60 and 90 (P > 0.05). CONCLUSION: Bio-C Pulpecto was biocompatible, induced biomineralization and was immunopositive for osteogenic markers such as OCN, OPN, and BSP, similarly to MTA.
