1.
J Nat Prod
; 66(10): 1382-3, 2003 Oct.
Article
in English
| MEDLINE
| ID: mdl-14575442
ABSTRACT
An efficient and highly stereoselective synthesis of cytotoxic 8-epipuupehedione (1b) was achieved starting from natural (-)-drimenol (6). The key step to obtain stereoselectivity was the simultaneous demethylation and oxidation of the dihydrobenzopyran methoxy derivatives 10a and 10b.