ABSTRACT
OBJECTIVE: In the majority of cases, the correct treatment of brain lesions is possible only when the histopathological diagnosis is made. Several deep-seated lesions near eloquent areas are not safely approached by the classical neurosurgical procedures. These patients can get benefit by a minimally invasive procedure. METHOD: We present a series of 176 consecutive patients submitted to stereotactic biopsies due to a great variety of brain lesions. RESULTS: Histological diagnosis found in this series: glioma in 40.1% of the patients, other neoplasms in 12.2% and infectious or inflammatory diseases in 29.1 %. The result was inconclusive in 5.2% of the procedures. One patient died (0.6%) and two (1.2%) presented operative complications. The criteria, advantages and risks of the stereotactic biopsies are discussed. CONCLUSION: The efficacy of the method is adequate and morbid-mortality rates were low.
Subject(s)
Biopsy/methods , Brain Neoplasms/pathology , Brain/pathology , Glioma/pathology , Stereotaxic Techniques , Adolescent , Adult , Aged, 80 and over , Biopsy/adverse effects , Biopsy/mortality , Brain Neoplasms/surgery , Child , Glioma/surgery , Humans , Male , Middle Aged , Stereotaxic Techniques/adverse effects , Stereotaxic Techniques/mortality , Young AdultABSTRACT
OBJECTIVE: In the majority of cases, the correct treatment of brain lesions is possible only when the histopathological diagnosis is made. Several deep-seated lesions near eloquent areas are not safely approached by the classical neurosurgical procedures. These patients can get benefit by a minimally invasive procedure. METHOD: We present a series of 176 consecutive patients submitted to stereotactic biopsies due to a great variety of brain lesions. RESULTS: Histological diagnosis found in this series: glioma in 40.1 percent of the patients, other neoplasms in 12.2 percent and infectious or inflammatory diseases in 29.1 percent. The result was inconclusive in 5.2 percent of the procedures. One patient died (0.6 percent) and two (1.2 percent) presented operative complications. The criteria, advantages and risks of the stereotactic biopsies are discussed. CONCLUSION: The efficacy of the method is adequate and morbid-mortality rates were low.
OBJETIVO: O diagnóstico anatomopatológico das lesões encefálicas é muitas vezes necessário para a instituição do tratamento adequado. Entretanto, muitas lesões localizadas profundamente no encéfalo ou em centros nervosos de grande importância funcional não podem ser acessadas sem riscos, com a aplicação dos procedimentos neurocirúrgicos habituais. MÉTODO: Apresentamos uma série de 176 doentes submetidos a biópsias estereotáxicas de lesões encefálicas. RESULTADOS: Em 40,1 por cento dos casos, o diagnóstico foi de glioma, em 12,2 por cento de outras neoplasias e em 29,1 por cento, de doenças infecciosas ou inflamatórias. O resultado foi inconclusivo em 5,2 por cento dos doentes. Um (0,6 por cento) doente faleceu e dois (1,2 por cento) apresentaram graves complicações operatórias. Os critérios de seleção, as vantagens e os riscos da biópsia estereotáxica são discutidos. CONCLUSÃO: A eficácia do método é boa e a morbimortalidade das biópsias estereotáxicas é baixa.
Subject(s)
Adolescent , Adult , Aged, 80 and over , Child , Humans , Male , Middle Aged , Young Adult , Biopsy/methods , Brain Neoplasms/pathology , Brain/pathology , Glioma/pathology , Stereotaxic Techniques , Biopsy/adverse effects , Biopsy/mortality , Brain Neoplasms/surgery , Glioma/surgery , Stereotaxic Techniques/adverse effects , Stereotaxic Techniques/mortality , Young AdultABSTRACT
O objetivo deste estudo é analisar a evolução de pacientes com hematoma subdural crônico em relação aos achados do coagulograma. Foram analisados 161 pacientes operados no Hospital das Clínicas-UNICAMP entre abril de 1994 e 2000. Foi detectado um predomínio do sexo masculino (86,3 por cento), da cor branca (85,1 por cento) e da faixa etária na quinta década (mediana 57 anos). O estudo mostrou mortalidade maior no período pós-operatório entre os pacientes com valores de RNI (international normalized ratio) superiores a 1,25 e/ou trombocitopenia (p<0,001 e p=0,004, respectivamente) e mortalidade menor para os pacientes com antecedente de traumatismo cranioencefálico (76 por cento) (p=0,044). Os resultados ressaltam a importância da avaliação pré-operatória com o coagulograma a fim de se corrigir possíveis alterações
Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Blood Coagulation , Hematoma, Subdural, Chronic/mortality , Hematoma, Subdural, Chronic/surgery , Age Distribution , Age Factors , Blood Coagulation Tests , Brazil/epidemiology , Craniocerebral Trauma/complications , Glasgow Coma Scale , Hematoma, Subdural, Chronic/blood , Postoperative Complications , Retrospective Studies , Sex Distribution , Sex FactorsABSTRACT
The chronic subdural hematoma represents one of the most frequent types of intracranial hemorrhage. One hundred sixty one patients operated in the Clinical Hospital of State University of Campinas-SP (UNICAMP) from April 1994 to May 2000, were analyzed retrospectively in order to characterize the population and to study the importance of the pre-operative coagulation analysis in the outcome. The majority of the population was male (86%), white (85.1%) and in the fifth decade (median age: 57 years). A high mortality index in the postoperative period was found in patients with INR (international normalized ratio) values greater than 1.25 and/or thrombocytopenia (p<0.001 and p=0.004 respectively). Patients with previous head injury history (76%) showed a lower mortality (p=0.044). The results stand out the importance of the pre-operative evaluation with coagulation studies in order to correct possible abnormalities.
Subject(s)
Blood Coagulation , Hematoma, Subdural, Chronic/blood , Hematoma, Subdural, Chronic/mortality , Adolescent , Adult , Age Distribution , Age Factors , Aged , Aged, 80 and over , Brazil/epidemiology , Child , Child, Preschool , Craniocerebral Trauma/complications , Female , Glasgow Coma Scale , Hematoma, Subdural, Chronic/surgery , Humans , Infant , Infant, Newborn , Male , Middle Aged , Retrospective Studies , Sex Distribution , Sex FactorsABSTRACT
A doença de mayamoya é anormalidade cerebrovascular crônica e progressiva identificada através das características angiográficas; estão presentes no quadro clínico episódios isquêmicos transitórios, cefaléia, crises convulsivas, hemiparesia, que podem desaparecer após tratamento cirúrgico. Nós descrevemos o caso de uma menina com características clássicas da doença, comparando-o em dois momentos, antes e depois da cirurgia, através de avaliações neurológicas, neuropsicológicas, e exames complementares.