Inventário de ansiedade Traço-Estado de gestantes / State-Trait anxiety inventory of pregnant women

Objetivo: identificar o nível de ansiedade e o perfil das gestantes usuárias do Sistema Único de Saúdede Pontal do Araguaia, Mato Grosso. Métodos: pesquisa descritiva e exploratória com abordagemquantitativa a 53 gestantes usuárias do serviço de pré-natal de Pontal do Araguaia, realizou-se acoleta de dados com entrevista semiestruturada, aplicou-se o Inventário de Ansiedade Traço-Estado.Resultados: houve o predomínio de primigestas jovens, pardas, do lar, ou seja, sem emprego formal,casadas, com ensino médio, renda familiar até dois salários mínimos. Não houve correlação positivaentre a situação da gestante no mercado de trabalho e o escore de ansiedade, as casadas possuemestado ansioso menor do que as em união consensual e as gestantes negras possuem estado ansiosoelevado. Conclusões: ser casada implica menores níveis ansiogênicos, enquanto ser negra implica maiores níveis ansiogênicos.

Objective: to identify the level of anxiety and the profile of pregnant women users of the UnifiedHealth System of Pontal do Araguaia, Mato Grosso. Methods: descriptive and exploratory researchwith a quantitative approach to 53 pregnant women users of the prenatal service of Pontal doAraguaia. The data collection was performed with semi-structured interview. The State-TraitAnxiety Inventory was applied. Results: there was a predominance of primigravid young, brown,housework at home, that is, without formal employment, married, with high school, family incomeup to two minimum wages. There was no positive correlation between the situation of the pregnantwoman in the labor market and the anxiety score. The married women had an anxious state lowerthan those in a consensual union and the black pregnant women had an elevated anxious state.Conclusions: being married implies lower anxiety levels while being black implies higher anxiogenic levels.

Effect of cellulose nanocrystals and gelatin in corn starch plasticized films.

Cellulose at the nanoparticle scale has been studied as a reinforcement for biodegradable matrices to improve film properties. The goal has been to investigate the properties of starch/gelatin/cellulose nanocrystals (CNC) films. Eleven treatments were considered using RCCD (rotatable central composite design), in addition to four control treatments. For each assay, the following dependent variables were measured: water vapor permeability (WVP), thickness, opacity and mechanical properties. The microstructure and thermal properties of the films were also assessed. Increases in gelatin and CNC concentrations lead to increases in film thickness, strength and elongation at break. The films containing only gelatin in their matrix displayed better results than the starch films, and the addition of CNC had a positive effect on the assessed response variables. The films exhibited homogeneous and cohesive structures, indicating strong interactions between the filler and matrix. Films with low levels of gelatin and CNC presented the maximum degradation temperature.

Limb immobilization alters functional electrophysiological parameters of sciatic nerve.

Immobilization, used in clinical practice to treat traumatologic problems, causes changes in muscle, but it is not known whether changes also occur in nerves. We investigated the effects of immobilization on excitability and compound action potential (CAP) and the ultrastructure of the rat sciatic nerve. Fourteen days after immobilization of the right leg of adult male Wistar rats (n=34), animals were killed and the right sciatic nerve was dissected and mounted in a moist chamber. Nerves were stimulated at a baseline frequency of 0.2 Hz and tested for 2 min at 20, 50, and 100 Hz. Immobilization altered nerve excitability. Rheobase and chronaxy changed from 3.13 ± 0.05 V and 52.31 ± 1.95 µs (control group, n=13) to 2.84 ± 0.06 V and 59.71 ± 2.79 µs (immobilized group, n=15), respectively. Immobilization altered the amplitude of CAP waves and decreased the conduction velocity of the first CAP wave (from 93.63 ± 7.49 to 79.14 ± 5.59 m/s) but not of the second wave. Transmission electron microscopy showed fragmentation of the myelin sheath of the sciatic nerve of immobilized limbs and degeneration of the axon. In conclusion, we demonstrated that long-lasting leg immobilization can induce alterations in nerve function.

Limb immobilization alters functional electrophysiological parameters of sciatic nerve

Immobilization, used in clinical practice to treat traumatologic problems, causes changes in muscle, but it is not known whether changes also occur in nerves. We investigated the effects of immobilization on excitability and compound action potential (CAP) and the ultrastructure of the rat sciatic nerve. Fourteen days after immobilization of the right leg of adult male Wistar rats (n=34), animals were killed and the right sciatic nerve was dissected and mounted in a moist chamber. Nerves were stimulated at a baseline frequency of 0.2 Hz and tested for 2 min at 20, 50, and 100 Hz. Immobilization altered nerve excitability. Rheobase and chronaxy changed from 3.13±0.05 V and 52.31±1.95 µs (control group, n=13) to 2.84±0.06 V and 59.71±2.79 µs (immobilized group, n=15), respectively. Immobilization altered the amplitude of CAP waves and decreased the conduction velocity of the first CAP wave (from 93.63±7.49 to 79.14±5.59 m/s) but not of the second wave. Transmission electron microscopy showed fragmentation of the myelin sheath of the sciatic nerve of immobilized limbs and degeneration of the axon. In conclusion, we demonstrated that long-lasting leg immobilization can induce alterations in nerve function.

One-week triple therapy with omeprazole plus azithromycin and secnidazole is ineffective in eradicating "helicobacter pylori"

Background: There is not yet consensus on the most effective treatment for the helicobacter pylori infection, particularly in most developing countries. Azithromycin is a new macrolide and relatively novel agent for H. pylori eradication with an in vitro MIC90 lower than 1 mg/ml.Secnidazole, a nitromidazole that causes fewer side effects than metronidazole, was recenty reported to be used, for the firt time, in the treatment of H. pylori infection. Aim: To evaluate, in a prospective, randomized, single-center study, the association of twodifferent doses of omeprazole, azithromycin and secnidazole in H. pylori eradication. Patients and methods: After informed consent, 55 patients (36m,19F) with duodenal ulcer associated with H. pylori infection were randomized to receive omeprazole 20mg uid (Group A) or 20mg bid (Group B) for sevem days plus azithromycin 500mg uid for six days and secnidazole 2,000mg uid in the first, fourth and seventh day. The H. pylori status was assessed before and 60-90 days posttreatment using urease test, histology and 13C-urea breath test. Statistical analysis was performed by X² test. Results: The two groups had similar demographic characteristics. Fifty-five patients (36M, 19F) were enrolled. Six patients did not show-up for the second visit posttreatment. So, of the 49 evaluable patients, 25por cento (6/24) in Group A and 44por cento(11/25) in Group B wereeradicated, in a per protocol (PP) analysis. Intetion-to-treat (ITT) eradication rates were 21,4por cento (6/28) in Group A and 40.7por cento (11/27) im Group B. The differences betweem ITT and PP analysis from the two groups were not statistically significant. Conclusions: This study shows a very low eradication rate with the two regimens comprising of omeprazole, azithromycin and secnidazole and therefore, should not be recommended for thetreatment of H. pylori infection