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Biull Eksp Biol Med ; 104(10): 466-9, 1987 Oct.
Article in Russian | MEDLINE | ID: mdl-3676472

ABSTRACT

The influence of some cholinergic drugs has been studied during prophylactic treatment and the recovery period after acute hypobaric hypoxia (AHBH) on AHBH model. Cholinolytics and cholinomimetics were shown to produce different effects on the animal resistance to AHBH, their role in the formation of resistance to hypoxia depending on the type of animal, the extent of hypoxic damage and duration of the recovery period after primary AHBH. The experiments performed suggest an important role of cholinergic system in the formation of hypoxic resistance in animals.


Subject(s)
Air Pressure , Atmospheric Pressure , Hypoxia/physiopathology , Receptors, Cholinergic/physiology , Acute Disease , Animals , Atmosphere Exposure Chambers , Hypoxia/prevention & control , Male , Mice , Mice, Inbred CBA , Parasympatholytics/pharmacology , Physostigmine/pharmacology , Receptors, Cholinergic/drug effects , Time Factors
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