Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 6 de 6
Filter
Add more filters










Database
Language
Publication year range
6.
J Antibiot (Tokyo) ; 51(1): 33-40, 1998 Jan.
Article in English | MEDLINE | ID: mdl-9531985

ABSTRACT

Five novel metabolites, trichodenones A-C (1-3), harzialactone A (4) and B (5), have been isolated together with known R-mevalonolactone (6) from the culture broth of a strain of Trichoderma harzianum OUPS-N115 originally separated from the sponge Halichondria okadai. Their structures have been elucidated by spectral evidence. Among them, 1-3 exhibited significant cytotoxicity against cultured P388 cells.


Subject(s)
Antineoplastic Agents/chemistry , Antineoplastic Agents/isolation & purification , Cyclopentanes/chemistry , Cyclopentanes/isolation & purification , Lactones/isolation & purification , Porifera/microbiology , Trichoderma/chemistry , Animals , Antineoplastic Agents/pharmacology , Lactones/chemistry , Leukemia P388/drug therapy , Mice , Trichoderma/isolation & purification , Trichoderma/metabolism
SELECTION OF CITATIONS
SEARCH DETAIL
...