Leptomeningeal Metastasis Mimicking a Subacute Epidural Hematoma: Case Report.

Leptomeningeal carcinomatosis is extremely rare in colorectal adenocarcinoma, its incidence is far less than 1%. The neurological symptoms are pleomorphic. The most common symptoms included Headache, ataxia, cranial nerve palsies, meningismus, focal weakness or numbness. MRI is the most sensitive and specific imaging method for screening, positive diagnosis and pre-treatment of leptomeningeal carcinomatosis. The presence of appropriate neuroimaging abnormalities in a patient with typical clinical features and history of colorectal adenocarcinoma enables to make the diagnosis of leptomeningeal metastases. As well as a biological confirmation is necessary. Treatment usually comprises site-specific radiation therapy in addition to intrathecal and systemic chemotherapy. The case aims to describe the MRI characteristics of leptomeningeal metastases so as to formulate the diagnosis and the subsequent treatment.

Second primary squamous cell carcinoma of nasal cavity after successful curative radiotherapy and chemotherapy of cancer of the cavum (UCNT).

After nasopharyngeal carcinoma treatment, secondary malignant tumors of the nasal cavities in the irradiated zone are extremely rare, with an estimated frequency of 0.15%-0.75%. They are more common in young persons who do not have traditional risk factors. The clinical symptomatology is dominated by nasal obstruction. The major goal of the CT-MRI imaging workup is to figure out the optimal treatment plan. However, histological confirmation of the diagnosis is required. The purpose of this case report is to explain the radiological characteristics of squamous cell carcinoma as seen on MRI, as well as to examine the literature on the carcinogenic risk of radiotherapy and chemotherapy.