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1.
Braz. j. oral sci ; 9(4): 459-463, Oct.-Dec. 2010. tab
Article in English | LILACS, BBO - Dentistry | ID: lil-582278

ABSTRACT

Temporomandibular disorders (TMD) is a term applied to functional changes of the temporomandibular joint (TMJ) and associated structures of mastication. Aim: To investigate the correlation between body mass index (BMI) and TMD in children. Methods: 70 children between 6 and 14 years enrolled in the Rogationist Benevolent Institute of charity in the city of São Paulo (Brazil) underwent clinical examination by one calibrated examiner for the use of Research Diagnostic Criteria for TMD. Weight and height were determined by anthropometric assessment for the diagnosis of nutritional status, and BMI was calculated by dividing weight in kilograms by height in meters squared (kg/m2). Descriptive analysis (mean and standard deviation) was used to characterize the sample. ANOVA complemented by the Least Significant Difference test was used to compare the mean anthropometric measurements between the genders and the groups with and without TMD. The significance level was set at 0.05. Results: We found a significantly high prevalence of TMD, as well as a significant association between TMD light and low body weight. Conclusions: The results show a high prevalence of TMD and a slight association between TMD and children with low body weight.


Subject(s)
Humans , Child , Adolescent , Body Mass Index , Sex Factors , Temporomandibular Joint Disorders/diagnosis , Analysis of Variance , Cross-Sectional Studies , Facial Pain/diagnosis , Masticatory Muscles
2.
J Pediatr (Rio J) ; 85(5): 449-54, 2009.
Article in English, Portuguese | MEDLINE | ID: mdl-19830359

ABSTRACT

OBJECTIVE: To compare iron absorption from infant formula and iron-fortified cow's milk. METHODS: Twenty-four weanling Wistar rats were maintained in metabolic cages during the whole experiment (10 days). On the first day, the animals were divided into three similar groups according to their weight, length, hematocrit and hemoglobin levels: 1) infant formula; 2) powdered whole cow's milk fortified with iron in the same quantity and type as the formula; 3) control--powdered whole cow's milk not fortified with iron. Deionized water and diet were offered ad libitum and the volume consumed was measured. Weight, hematocrit, and hemoglobin levels were measured on the fifth and 10th days when length, fecal occult blood, and hepatic iron levels were also analyzed. RESULTS: Group 1 consumed less diet (450.5+/-26.50 mL) than group 2 (658.8+/-53.73 mL) and control group (532.7+/-19.06 mL, p < 0.001). Hemoglobin levels were higher (p < 0.001) in group 1 (12.1+/-1.13 g/dL) than in group 2 (9.6+/-1.59 g/dL) and in control group (6.2+/-0.97 g/dL). Hepatic iron level showed the same pattern as hemoglobin (p < 0.001). There was no difference in weight and length between the three groups (p = 0.342). There was no fecal occult blood in the any of the animals. CONCLUSIONS: Despite the lower volume consumed, the group that received formula presented higher iron absorption and hemoglobin levels than the group fed with fortified whole cow's milk. Growth was similar in the three groups.


Subject(s)
Food, Fortified , Infant Formula/chemistry , Iron, Dietary/administration & dosage , Iron/pharmacokinetics , Milk/chemistry , Analysis of Variance , Animals , Hemoglobins/analysis , Male , Models, Theoretical , Rats , Rats, Wistar , Statistics, Nonparametric , Weaning
3.
J. pediatr. (Rio J.) ; 85(5): 449-454, set.-out. 2009. graf, tab
Article in Portuguese | LILACS | ID: lil-530123

ABSTRACT

OBJETIVO: Comparar a absorção do ferro da fórmula de partida e do leite de vaca integral fortificado. MÉTODOS: Foram utilizados 24 ratos machos Wistar recém-desmamados, mantidos em gaiolas metabólicas durante todo o período do experimento (10 dias). No primeiro dia, os animais foram distribuídos em três grupos semelhantes quanto ao peso, comprimento, hematócrito e hemoglobina: 1) fórmula de partida para lactentes; 2) leite de vaca integral em pó fortificado com a mesma quantidade e tipo de sal de ferro da fórmula; e 3) controle - leite de vaca integral em pó não fortificado com ferro. Água e dieta foram oferecidas ad libitum com mensuração do volume consumido. Peso, hematócrito e hemoglobina foram mensurados no quinto e no 10º dia do experimento, quando foram analisados também comprimento, sangue oculto nas fezes e teor de ferro hepático. RESULTADOS: O grupo 1 ingeriu menor volume de dieta (450,5±26,50 mL) que os grupos 2 (658,8±53,73 mL) e controle (532,7±19,06 mL; p < 0,001). As concentrações de hemoglobina foram maiores (p < 0,001) no grupo 1 (12,1±1,13 g/dL) que nos grupos 2 (9,6±1,59 g/dL) e controle (6,2±0,97 g/dL). O teor de ferro hepático apresentou o mesmo comportamento da hemoglobina (p < 0,001). Não foi observada diferença de peso e comprimento nos três grupos (p = 0,342). Não foi detectado sangue oculto nas fezes de nenhum dos animais. CONCLUSÕES: Apesar do menor volume ingerido, o grupo que recebeu fórmula apresentou maior absorção de ferro e concentração de hemoglobina que o grupo que recebeu leite de vaca integral fortificado. O crescimento foi semelhante nos três grupos.


OBJECTIVE: To compare iron absorption from infant formula and iron-fortified cow's milk. METHODS: Twenty-four weanling Wistar rats were maintained in metabolic cages during the whole experiment (10 days). On the first day, the animals were divided into three similar groups according to their weight, length, hematocrit and hemoglobin levels: 1) infant formula; 2) powdered whole cow's milk fortified with iron in the same quantity and type as the formula; 3) control - powdered whole cow's milk not fortified with iron. Deionized water and diet were offered ad libitum, and the volume consumed was measured. Weight, hematocrit, and hemoglobin levels were measured on the fifth and 10th days when length, fecal occult blood, and hepatic iron levels were also analyzed. RESULTS: Group 1 consumed less diet (450.5±26.50 mL) than group 2 (658.8±53.73 mL) and control group (532.7±19.06 mL, p < 0.001). Hemoglobin levels were higher (p < 0.001) in group 1 (12.1±1.13 g/dL) than in group 2 (9.6±1.59 g/dL) and in control group (6.2±0.97 g/dL). Hepatic iron level showed the same pattern as hemoglobin (p < 0.001). There was no difference in weight and length between the three groups (p = 0.342). There was no fecal occult blood in the any of the animals. CONCLUSIONS: Despite the lower volume consumed, the group that received formula presented higher iron absorption and hemoglobin levels than the group fed with fortified whole cow's milk. Growth was similar in the three groups.


Subject(s)
Animals , Male , Rats , Food, Fortified , Infant Formula/chemistry , Iron, Dietary/administration & dosage , Iron/pharmacokinetics , Milk/chemistry , Analysis of Variance , Hemoglobins/analysis , Models, Theoretical , Rats, Wistar , Statistics, Nonparametric , Weaning
4.
J Sports Sci ; 26(11): 1209-17, 2008 Sep.
Article in English | MEDLINE | ID: mdl-18645734

ABSTRACT

In this cross-sectional study, we evaluated the body composition and dietary intake of 44 adolescent tennis players. After being divided into two groups (age 10-13 years and age 14-18), the players had their weight, height, and sexual maturation assessed. Dual-energy X-ray absorptiometry was used to assess body composition. Food intake was obtained from a non-consecutive 4-day food record. The data were analysed using the Virtual Nutri v.1.0 software and compared with the present recommendations for adolescent athletes or dietary reference intakes. Body mass index and body fat for tennis practice were adequate for 89% and 71% of the tennis players respectively, regardless of age group. A calorie deficit greater than 10% of energy expenditure was observed in 32% of the sample. Fifty percent of the athletes consumed carbohydrates in accordance with recommended values. Protein and lipid intakes were above recommended values, while fibre, calcium, potassium, magnesium, and folic acid intakes were below recommendation for 98%, 80%, 100%, 100%, and 98% of the tennis players respectively. The observed nutritional deficiencies represent an additional barrier for adolescents engaged in competitive sports to achieve an optimum nutrition to maintain growth, health, and performance.


Subject(s)
Body Composition/physiology , Nutritional Status , Tennis/physiology , Absorptiometry, Photon , Adolescent , Age Factors , Anthropometry , Child , Energy Metabolism , Humans , Male , Prospective Studies
6.
Rev Assoc Med Bras (1992) ; 53(4): 323-8, 2007.
Article in Portuguese | MEDLINE | ID: mdl-17823735

ABSTRACT

OBJECTIVE: To assess the anthropometry, body composition and iron, copper and zinc nutritional status, according to gender, of institutionalized children and adolescents living in two shantytowns in the city of Sao Paulo. METHODS: A cross sectional study using weight, height, arm circumference, skinfolds, electrical bioimpedance, Z scores for the relationships: height to age, body mass index, middle-upper arm circumference, muscle area of the arm and fat area of the arm was carried out; the body fat and lean mass percentages were analyzed according to the formulas proposed by Siri and Slaughter. Hemoglobin, hematocrit, serum iron ferritin, copper and zinc were determined. RESULTS: Body weight, middle-upper arm circumference, triceps and subescapular skinfolds, electric resistance, Z scores of the arm area, muscle area of the arm, and body fat percentage of girls were higher in relation to boys. Low stature was found in 8% of the girls and in 5.6% of the boys, without differences according to gender. There was a lower prevalence of malnutrition (2% of the girls and 5.6% of the boys), than of overweight and obesity (30% and 11.2%, respectively). Anemia was observed in 24.4% and iron deficiency in 10.5% of the schoolchildren with or without anemia. Values were below the lower limit of the reference standard for serum copper and zinc, respectively, for 3 and 7 individuals. CONCLUSION: In the studied population, institutionalized and of low social economic level, a process of nutritional transition and high prevalence of anemia takes place which does not result from an interaction of iron, copper and zinc.


Subject(s)
Body Weights and Measures , Nutritional Status/physiology , Transition Elements/blood , Adolescent , Anemia, Iron-Deficiency/diagnosis , Anemia, Iron-Deficiency/epidemiology , Body Height/physiology , Body Mass Index , Brazil/epidemiology , Child , Copper/blood , Epidemiologic Methods , Female , Humans , Iron/blood , Male , Obesity/diagnosis , Obesity/epidemiology , Sex Distribution , Skinfold Thickness , Socioeconomic Factors , Zinc/blood
7.
Rev. Assoc. Med. Bras. (1992, Impr.) ; 53(4): 323-328, jul.-ago. 2007. tab
Article in Portuguese | LILACS | ID: lil-460303

ABSTRACT

OBJETIVO: Avaliar a antropometria, a composição corporal e o estado nutricional em ferro, cobre e zinco segundo o gênero, de crianças e adolescentes institucionalizados, moradores de duas favelas da cidade de São Paulo. MÉTODOS: Estudo transversal utilizando medidas de peso, estatura, circunferência braquial, dobras cutâneas, bioimpedância elétrica, os escores Z da relação estatura para idade, índice de massa corporal, área do braço, área muscular do braço e área de gordura do braço. Os percentuais de gordura corporal e massa magra foram analisados segundo fórmulas de Siri e Slaughter. Foram determinados hemoglobina, hematócrito, ferro, ferritina, cobre e zinco séricos. RESULTADOS: Foram maiores o peso corporal, circunferência do braço, dobras cutâneas do tríceps e subescapular, resistência elétrica, escores Z da área do braço, área muscular do braço e percentual de gordura corporal no sexo feminino em relação ao masculino. Baixa estatura foi encontrada em 8 por cento das meninas e 5,6 por cento dos meninos, sem diferença quanto ao gênero. Houve menor prevalência de desnutrição (2 por cento das meninas e 5,6 por cento nos meninos), do que de sobrepeso e obesidade (30 por cento e 11,2 por cento, respectivamente). Observou-se anemia em 24,4 por cento e ferropenia em 10,5 por cento dos escolares com ou sem anemia. Apresentaram valores abaixo do limite inferior do padrão de referência para cobre e zinco séricos, respectivamente três e sete indivíduos. CONCLUSÃO: Na população estudada, de baixo nível econômico e institucionalizada, ocorre o processo de transição nutricional e alta prevalência de anemia que não resulta da interação ferro, cobre e zinco.


OBJECTIVE: To assess the anthropometry, body composition and iron, copper and zinc nutritional status, according to gender, of institutionalized children and adolescents living in two shantytowns in the city of Sao Paulo. METHODS: A cross sectional study using weight, height, arm circumference, skinfolds, electrical bioimpedance, Z scores for the relationships: height to age, body mass index, middle-upper arm circumference, muscle area of the arm and fat area of the arm was carried out; the body fat and lean mass percentages were analyzed according to the formulas proposed by Siri and Slaughter. Hemoglobin, hematocrit, serum iron ferritin, copper and zinc were determined. RESULTS: Body weight, middle-upper arm circumference, triceps and subescapular skinfolds, electric resistance, Z scores of the arm area, muscle area of the arm, and body fat percentage of girls were higher in relation to boys. Low stature was found in 8 percent of the girls and in 5.6 percent of the boys, without differences according to gender. There was a lower prevalence of malnutrition (2 percent of the girls and 5.6 percent of the boys), than of overweight and obesity (30 percent and 11.2 percent, respectively). Anemia was observed in 24.4 percent and iron deficiency in 10.5 percent of the schoolchildren with or without anemia. Values were below the lower limit of the reference standard for serum copper and zinc, respectively, for 3 and 7 individuals. CONCLUSION: In the studied population, institutionalized and of low social economic level, a process of nutritional transition and high prevalence of anemia takes place which does not result from an interaction of iron, copper and zinc.


Subject(s)
Adolescent , Child , Female , Humans , Male , Body Weights and Measures , Nutritional Status/physiology , Transition Elements/blood , Anemia, Iron-Deficiency/diagnosis , Anemia, Iron-Deficiency/epidemiology , Body Height/physiology , Body Mass Index , Brazil/epidemiology , Copper/blood , Epidemiologic Methods , Iron/blood , Obesity/diagnosis , Obesity/epidemiology , Sex Distribution , Skinfold Thickness , Socioeconomic Factors , Zinc/blood
8.
J Pediatr (Rio J) ; 80(3): 183-8, 2004.
Article in Portuguese | MEDLINE | ID: mdl-15192760

ABSTRACT

OBJECTIVE: To compare the effect of soy polysaccharide on fecal weight and humidity in growing rats in relation to cellulose and a Soy formula without dietary fiber. METHODS: Twelve, 21-day-old, Wistar male rats, were distributed into three groups and fed AIN-93G ration with varying amounts of dietary fiber: Polysaccharide Group, 5% fiber in the form of soy polysaccharide; Soy Formula Group, 5% soy formula without fiber; and Cellulose Group, 5% fiber in cellulose form. Feces were collected for three 72-hour periods beginning on days 7, 17 and 27. They were weighed while humid and then dried at 105 degrees C until a constant weight. The humidity was calculated using the formula [(humid fecal weight - dry fecal weight)/humid fecal weight] X 100. RESULTS: The total humid fecal weight for Polysaccharide, Soy Formula and Cellulose groups was: 17.372-/+4.743 g; 6.045-/+0.619 g; and 16.012-/+2.600 g, (p = 0.001), respectively. There was no statistically significant difference between the Cellulose and Polysaccharide groups, but a statistically significant difference was observed between theses two groups and the soy formula group. Values for dry weight, in the same order, were: 6.463-/+1.177 g; 2.909-/+0.277 g; and 10.068-/+1.085 g, (p < 0.001), with a statistically significant difference between each of the groups. CONCLUSION: Animals that received soy formula presented lower humid and dried fecal weight than the other two groups, while the soy polysaccharide caused higher fecal humidity than did cellulose, probably due to greater fermentation.


Subject(s)
Defecation/drug effects , Dietary Fiber/pharmacology , Feces , Polysaccharides/pharmacology , Soybean Proteins/pharmacology , Analysis of Variance , Animal Feed/analysis , Animals , Cellulose/pharmacology , Feces/chemistry , Male , Rats , Rats, Wistar , Glycine max/chemistry
9.
J. pediatr. (Rio J.) ; 80(3): 183-188, maio-jun. 2004. tab
Article in Portuguese | LILACS | ID: lil-362579

ABSTRACT

OBJETIVO: Comparar, em ratos, o efeito do polissacarídeo de soja em relação a celulose e fórmula de soja sem fibra alimentar sobre o peso e a umidade fecal. MÉTODOS: Foram utilizados 12 ratos Wistar machos, com 21 dias de vida, distribuídos em três grupos, que receberam ração AIN-93G variando-se a fonte de fibra alimentar: grupo polissacarídeo, com 5 por cento de fibra na forma de polissacarídeo de soja; grupo fórmula de soja, com 5 por cento de fórmula de soja sem fibra; e grupo celulose, com 5 por cento de fibra na forma de celulose. As fezes foram coletadas em três períodos de 72 horas iniciados no 7º, 17º e 27º dia. As mesmas foram pesadas frescas e após secagem em estufa a 105 ºC até peso constante. A umidade foi calculada usando a fórmula [(peso fecal úmido - peso fecal seco)/peso fecal úmido] x 100. RESULTADOS: As somas do peso fecal úmido nos grupos polissacarídeo, fórmula de soja e celulose foram, respectivamente: 17,372±4,743 g; 6,045±0,619 g; 16,012±2,600 g (p = 0,001), observando-se diferença estatisticamente significante dos grupos celulose e polissacarídeo em relação ao grupo fórmula de soja. Não houve diferença estatisticamente significante entre os grupos celulose e polissacarídeo. Para o peso seco, na mesma ordem, observou-se: 6,463±1,177 g; 2,909±0,277 g; 10,068±1,085 g (p < 0,001), com diferença estatisticamente significante entre todos os grupos. CONCLUSAO: Os animais que receberam fórmula de soja apresentaram peso fecal úmido e seco inferior ao dos outros dois grupos, enquanto o polissacarídeo de soja determinou umidade fecal superior à da celulose, provavelmente por maior fermentação no cólon.


Subject(s)
Animals , Male , Rats , Defecation/drug effects , Dietary Fiber/pharmacology , Feces/chemistry , Polysaccharides/pharmacology , Soybean Proteins/pharmacology , Analysis of Variance , Animal Feed/analysis , Cellulose/pharmacology , Rats, Wistar , Glycine max/chemistry
10.
J. pediatr. (Rio J.) ; 78(4): 327-334, jul.-ago. 2002. tab
Article in Portuguese | LILACS | ID: lil-322742

ABSTRACT

Objetivo: verificar o estado nutricional relativo ao ferro, cobre e zinco e a correlação entre índice de massa corporal, níveis séricos e dietéticos desses elementos, em adolescentes durante o estirão pubertário.Métodos: estudo descritivo, do tipo corte transversal, envolvendo uma amostra de 47 adolescentes atendidos em ambulatório deadolescência clínica, durante o período de março a dezembro de 1999, que se apresentavam no estirão pubertário, do total de 360 que freqüentaram o ambulatório no período, sendo 19 rapazes na faixa etária de 12,3 a 16 anos, e 28 moças na faixa etária de 11,1 a 13,6 anos. Variáveis analisadas: dietética (recordatório de 24 horas, freqüência e registro alimentar) para determinar a ingestão de ferro, cobre e zinco; antropométrica (peso e altura) para aferição do índice de massa corporal; bioquímica (dosagem sérica de ferro pelo kit in vitro Diagnóstica, ferritina pelo kit Immulite, cobre e zinco por espectrofotometria de absorção atômica). Utilizou-se o coeficiente de Spearman para análise estatistíca. esultados: dos 47 adolescentes em estirão pubertário, apresentaram ingestão adequada de: ferro (95por cento e 36por cento), cobre (53por cento e 57por cento) e zinco (21por cento e 21por cento) nos sexos masculino e feminino, respectivamente. A maioria dos adolescentes era eutrófica segundo os percentis do IMC. Bioquimicamente, os rapazes apresentaram valores normais para ferro e zinco em toda a amostra; para cobre em 95por cento e para ferritina em 84por cento. As moças também apresentaram valores normais de ferro e zinco; para cobre em 96,4por cento e para ferritina em 96por cento. Não houve correlação estatisticamente significante entre IMC concentração sérica de ferro, ferritina, cobre e zinco, e entreconcentração sérica e ingestão dietética dos minerais estudados, nem tampouco para a relação ferro sérico e ferritina. Conclusões: não se sabe, até o momento, se os níveis séricos de zinco e cobre flutuam durante o crescimento, ou se cada indivíduo tem um nível estável destes minerais durante o estirão. Os níveis séricos normais de ferro, cobre e zinco na maioria dos adolescentes avaliados podem estar refletindo a habilidade do organismo em fazer ajustes homeostáticos


Subject(s)
Humans , Male , Female , Adolescent , Copper , Growth , Iron , Zinc
11.
J Pediatr (Rio J) ; 78(4): 327-34, 2002.
Article in Portuguese | MEDLINE | ID: mdl-14647765

ABSTRACT

OBJECTIVE: To examine iron, copper and zinc nutritional status and their correlation with Body Mass Index (BMI), serum and dietetic levels in adolescents during the pubertal growth spurt. METHODS: A descriptive cross-sectional study involving a sample of 47 adolescents out of 360 patients (19 boys, whose ages ranged from 12.3 to 16 years and 28 girls, whose ages ranged from 11.1 to 13.6 years), who were seen at a clinic for adolescents from March to December 1999. The variables analyzed were: Diet (24 hours Dietary Recall, Food Frequency Intake Questionnaire and Food Register Methods) to determine iron, copper and zinc intake; anthropometry (weight and height) to check BMI; biochemistry (measure of serum iron level through a Diagnóstica kit in vitro; ferritin through Immulite kit, and atomic absorption spectrophotometry for biochemical evaluation of serum iron, ferritin, copper and zinc. Spearman coefficient correlation was used for statistical analysis. RESULTS: Forty seven adolescents during pubertal growth spurt showed adequate ingestion: iron (95% and 36%), copper (53% and 57%) and zinc (21% and 21%) in males and females, respectively. Most of them were eutrophic according to the BMI percentiles. Biochemically, boys presented normal values for serum iron and zinc in the whole sample, 95% for copper and 84% for ferritin. Girls also presented normal values for iron and zinc values in the whole sample, 96.4% for copper and 96% for ferritin. There were no statistically significant correlation between BMI and serum Fe, ferritin, Cu and Zn concentrations and between serum concentration and dietetic ingestion of the studied minerals, neither between serum iron and ferritin. CONCLUSIONS: It is not clear if serum levels of Zn and Cu are floating during the growth process or if each adolescent has a stable level of these minerals during the pubertal growth spurt. Normal Fe, Cu and Zn serum levels in most adolescents evaluated may reflect the organism ability to accomplish homeostatic adjustments.

12.
J. pediatr. (Rio J.) ; 75(5): 350-6, set.-out. 1999. graf
Article in Portuguese | LILACS | ID: lil-251409

ABSTRACT

Objetivo: Estudar o músculo esquelético (ME) de recém-nascidos desnutridos intra-uterinos através de biopsia muscular com estudo histoquímico. Material e Métodos: Utilizaram-se ratas Wistar EPM-1, 90 dias, peso 200 ñ 20g, desnutridas durante toda gestaçäo. No 21§ dia de gestaçäo foi colhida biopsia do músculo biceps braquii dos recém-nascidos (RN), obtidos por cesária (1ª geraçäo). Um grupo de RN desnutridos foi recuperado nutricionalmente após o nascimento, pela permanência de seis filhotes/rata nutriz e pela alimentaçäo ad labitum até o 90§ dia de vida, quando as fêmeas foram colocadas para cruzamento, originando os recém-nascidos da 2ª geraçäo. Resultados: O ganho de peso durante a gestaçäo e o peso do RN foram significativamente diferentes quando comparados cada grupo desnutrido ao seu respectivo grupo controle. As biopsias musculares dos RN desnutridos intra-uterinos apresentaram comprometimento como perda do predomínio de fibra tipo II, dimuiçäo do diâmetro das fibras musculares, baixa atividade oxidativa, proliferaçäo de tecido intersticial e edema. Na segunda geraçäo, os recém-nascidos apresentaram peso corporal adequado, mas mantinham o comprometimento do tecido muscular como diminuiçäo do predomínio de fibras tipo II, diminuiçäo do diâmetro das fibras musculares, baixa atividade oxidativa, presença de aumento de espaço intersticial, aumento de necrose mas sem edema. Conclusäo: A desnutriçäo energética na fase intra-uterina afeta diretamente o ME, podendo causar alteraçöes irreversíveis que se repetem na geraçäo seguinte, indicando a gravidade de a desntriçäo ocorrer na fase crítica de desenvolvimento do tecido muscular


Subject(s)
Animals , Rats , Biopsy , Metabolism , Muscle, Skeletal , Nutrition Disorders , Rats
13.
J. pediatr. (Rio J.) ; 73(5): 305-10, set.-out. 1997. tab, graf
Article in Portuguese | LILACS | ID: lil-211786

ABSTRACT

Objetivo: Verificar o "status" do cobre em rata gestante desnutrida e na sua prole. Método: Utilizou-se ratas Wistar com idade de 90 dias e peso corporal de 200+-20g. Após confirmada a prenhez, esses animais por randonizaçäo , deram origem ao grupos gestantes controle-GC, desnutridos-GD1 (desnutriçäo grave), e GD2-(desnutriçäo leve), e os filhotes obtidos por cesária,formaram os grupos de recém-nascidos RNC, RND1 e RND2 respectivamente. Os tecidos coletados (fígado, músculo, osso, placenta e carcaça) sofreram digestäo líquida prévia e a determinaçäo de cobre nesses e no soro foi feita por espectrofometria de absorçäo atômica. Resultados: as concentraçöes de cobre sérico, ósseo, placentário e hepático mostraram diferença significantes entre os grupos gestantes...


Subject(s)
Animals , Rats , Copper/metabolism , Maternal Nutrition , Nutrition Disorders/diet therapy
14.
Rev. paul. pediatr ; 11(1): 153-6, mar. 1993. tab
Article in Portuguese | LILACS | ID: lil-224444

ABSTRACT

A existência de uma via de absorçäo intestinal comum para o ferro e o cobre poderia explicar os efeitos negativos da ferroterapia oral no estado nutricional de cobre, observados em animais de laboratório. Na deficiência de ferro ocorre aumento da absorçäo intestinal de ferro, que poderia prejudicar a absorçäo do cobre. O objetivo desse estudo é analisar a relaçäo entre a terapia com sulfato ferroso, em crianças com deficiência de ferro e o cobre corporal. Foram estudadas 31 crianças (idade mediana = 32 meses) que realizaram terapia com sulfato ferroso (5 mg/kg/dia) durante dois meses. A hemoglobina, o ferro sérico, a transferrina, a saturaçäo da transferrina e a ferritina apresentaram modificaçöes estatísticas no sentido do preenchimento dos compartimentos corporais de ferro. Os valores de cobre sérico, antes e depois da terapia com sulfato ferroso, foram, respectivamente, 162,43 ñ 27,2 e 148,7 ñ 25,3 (p=0,010 aproximadamente). A ceruloplasmina diminuiu de 45,5 ñ 10,7 ñ 7,1 (p=0,039 aproximadamente). Todos os valores individuais de cobre e ceruloplasmina se encontravam dentro dos limites da normalidade. Os números de leucócitos e neutrófilos näo mostraram variaçäo significante. Apesar da diminuiçäo estatística nos níveis de cobre e cerruloplamina, näo encontramos nenhuma justificativa que pudesse questionar a segurança da ferroterapia oral


Subject(s)
Humans , Female , Male , Infant , Child, Preschool , Child , Ceruloplasmin , Ferrous Sulfate , Copper/blood , Iron Deficiencies/therapy , Intestinal Absorption
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