ABSTRACT
INTRODUCTION: Pelvic actinomycosis is a rare suppurative disease that should be included in the differential diagnosis of gynecological cancers. CASE REPORTS: We report two women aged 40 and 41 years with pelvic tumor-like actinomycosis. Physical examination disclosed a pelvic mass in both cases. CT-scan showed annexial infiltrative tumor in both cases with liver metastasis and peritoneal carcinosis in one case each. Surgical procedure consisted in right annexectomy in one case and peritoneal biopsy in the other. Pathologic diagnosis was diagnostic of actinomycosis. Both patients were treated by penicillin G 20 million IU/day during two weeks and then by amoxicilline 3g/day per day during six months. Clinical outcome showed significant improvement in both cases with complete regression of hepatic and pelvic lesions on CT-scan in one case. CONCLUSION: Pelvic actinomycosis is a rare suppurative disorder, commonly associated with a long term wearing of intra-uterine device. Diagnosis is difficult, often delayed and pelvic actinomycosis could mimic gynaecologic neoplasia.
Subject(s)
Actinomycosis/complications , Actinomycosis/diagnosis , Intrauterine Devices/adverse effects , Liver Abscess/diagnosis , Liver Abscess/microbiology , Salpingitis/diagnosis , Salpingitis/microbiology , Actinomycosis/therapy , Adnexa Uteri/surgery , Adult , Anti-Bacterial Agents/therapeutic use , Diagnosis, Differential , Female , Humans , Pelvic Inflammatory Disease/diagnosis , Pelvic Inflammatory Disease/microbiology , Penicillin G/therapeutic use , Salpingitis/therapy , Treatment OutcomeABSTRACT
We examine the time-dependent distortion of a nearly circular viscous domain in an infinite viscous sheet when suction occurs. Suction, the driving force of the instability, can occur everywhere in the two phases separated by an interface. The model assumes a two-dimensional Stokes flow; the selection of the wavelength at short times is determined by a variational procedure. Contrary to the viscous fingering instability, undulations of the boundary may be observed for enough pumping, whatever the sign of the viscosity contrast between the two fluids involved. We apply our model to the suction by lipoproteins of cholesterol-enriched domains in giant unilamellar vesicles. Comparison of the number of undulations given by the model and by the experiments gives reasonable values of physical quantities such as the viscosities of the domains.
