ABSTRACT
OBJECTIVE: To cross-culturally adapt the Pediatric Asthma Therapy Assessment Questionnaire (ATAQ) into Brazilian Portuguese and analyze its measurement properties. METHODS: This exploratory methodological study included eight experts and 30 caregivers in the translation and cross-cultural adaptation steps. Thereafter, 118 caregivers of pediatric patients with asthma aged between 5 and 17 years were involved in the analysis of measurement properties. We analyzed the content, structural (exploratory and confirmatory factorial), construct (convergent and discriminant), and known-groups validities; floor and ceiling effects; and determined the cut-off point (receiver operator characteristic curve) to identify pediatric patients with uncontrolled asthma. Intraclass correlation coefficient (ICC) analyzed test-retest reliability with 54 caregivers, whereas Cronbach's α and composite reliability verified the internal consistency of the items. RESULTS: The committee of experts and caregivers found the instructions and response options relevant, understandable, and clear (K > 0.75). During the cross-cultural adaptation, three items (2, 4, and 12) were slightly modified by including terms to facilitate understanding. A two-factor structure (asthma control and patient-provider communication) was identified. Internal consistency (α > .67; composite reliability > 0.73) and test-retest reliability (ICC > 0.80) were acceptable. For construct and know-groups validities, 85.71% of the hypothesis were confirmed. A cut-off point of >3 for the control domain was considered adequate to identify pediatric patients with uncontrolled asthma (sensitivity: 86.21%; specificity: 80.90%). CONCLUSION: The Pediatric ATAQ was adequately adapted for Brazilian pediatric patients with asthma and produced valid and reliable measures for assessing asthma control. Therefore, it may be considered an adequate instrument for monitoring asthma control in the Brazilian pediatric population.
Subject(s)
Asthma , Cross-Cultural Comparison , Humans , Asthma/drug therapy , Child , Brazil , Surveys and Questionnaires , Adolescent , Male , Female , Reproducibility of Results , Child, Preschool , Translations , Caregivers , PsychometricsABSTRACT
Foi realizado um estudo em uma família natural do estado do Rio Grande do Norte (Brasil) com o objetivo de pesquisar a presença de hemoglobina S. Nesta Família constituída de 14 membros, a presença dessa hemoglobina foi pesquisada através do teste de falcizaçäo das hemácias e pela eletroforese de hemoglobina em acetato de celulose. Outros dados hematológicos foram obtidos pelos métodos rotineiros e, paralelamente, foram realizados exames clínicos com o objetivo de evidenciar sinais físicos relacionados com a presença da hemoglobina S. Constatou-se que a presença da hemoglobina S estava presente em alguns membros da família na forma heterozigoto (Hb-AS) tais como o avô materno, a avó paterna, ambos os pais e 3 dos filhos do casal e apenas um membro era portador dessa hemoglobina na forma homozigoto (Hb-SS)
