Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 11 de 11
Filter
1.
Rev. Nutr. (Online) ; 35: e210116, 2022. tab
Article in English | LILACS | ID: biblio-1387497

ABSTRACT

ABSTRACT Objective To evaluate factors associated with dietary practices in students of a institution of higher education, included in the PADu study: "Anxiety and depression symptoms among university students in Minas Gerais: a longitudinal study". Methods Cross-sectional study of PADu project baseline with undergraduate first period students, who responded in person to a printed and self-administered questionnaire. Dietary practices were evaluated through a 24 items scale based on recommendations of Dietary Guidelines for the Brazilian Population. Answer choices are four-point Likert scale: "strongly agree", "agree", "disagree" and "strongly disagree". The sum of the items corresponded a score ranging (0-72 points), a high score indicating greater adequacy. The explanatory variables were: sociodemographics (gender, age, knowledge area, skin color, marital status, monthly household income), behaviors (excess alcohol consumption, physical exercise, screen exposure, internet use), health conditions (self-rated health, nutritional status, symptoms of depression, anxiety, stress). Adjusted multiple linear regression model was used to estimate the coefficients and their 95% CI. Results 356 students participated in the study. The average of dietary practices was 34.9±9.3 (0-63) points. Physical exercise practice (β: 3.75; CI: 1.83; 5.67) was associated with higher scores in the eating students score. We observed factors associated with the lowest score greater exposure to screens (β: -0.44; CI: -0.67; -0.13), excessive internet use (β: -3.05; CI: -5.22; -0.88), poor health self-assessment (β: -3.63; CI: -4.97; -1.21), excessive alcohol consumption (β: -2.09; CI: -3.92;-0.26) and stress symptoms (β: -2.81; CI: -4.72; -0.77). Conclusion Most students have inadequate dietary practices associated with internet use, alcohol consumption and stress.


RESUMO Objetivo Avaliar os fatores associados às práticas alimentares em estudantes de uma instituição de Ensino Superior incluídos no estudo PADu: "Sintomas de ansiedade e depressão em universitários de Minas Gerais: um estudo longitudinal". Métodos Estudo transversal da linha de base do projeto PADu com alunos do primeiro período da graduação, que responderam pessoalmente a um questionário impresso e autoaplicável. As práticas alimentares desses estudantes foram avaliadas por meio de uma escala de 24 itens baseada nas recomendações do Guia Alimentar para a População Brasileira. As opções de resposta foram coletadas em escala Likert de quatro pontos: "concordo totalmente", "concordo", "discordo" e "discordo totalmente". A soma dos itens correspondeu a uma pontuação (0-72 pontos), onde uma pontuação alta indicava maior adequação. As variáveis explicativas foram: características sociodemográficas (sexo, idade, área do conhecimento, cor da pele, estado civil, renda familiar total mensal), comportamentos (consumo excessivo de álcool, exercícios físicos, exposição a telas e uso de internet) e condições de saúde (autoavaliação saúde, estado nutricional, sintomas de depressão, ansiedade e stress). O modelo de regressão linear múltipla ajustado foi usado para estimar os coeficientes e seus IC 95%. Resultados 356 alunos participaram do estudo. A média das práticas alimentares foi de 34,9±9,3 (0-63) pontos. A prática de exercícios físicos (β: 3,75; IC: 1,83; 5,67) esteve associada a maiores escores no escore de hábitos alimentares dos escolares. Foram observados fatores associados ao menor escore maior exposição a telas (β: -0,44; IC: -0,67; -0,13), uso excessivo de internet (β: -3,05; IC: -5,22; -0,88), ruim autoavaliação de saúde (β: -3,63; IC: -4,97; -1,21), consumo excessivo de álcool (β: -2,09; IC: -3,92; -0,26) e sintomas de estresse (β: -2,81; IC: -4,72; -0,77). Conclusão A maioria dos estudantes apresenta práticas alimentares inadequadas associadas ao uso da internet, consumo de álcool e estresse.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Students , Food Guide , Feeding Behavior/psychology , Sociodemographic Factors , Cross-Sectional Studies , Surveys and Questionnaires
2.
Nutr. hosp ; 38(1): 121-127, ene.-feb. 2021. tab
Article in English | IBECS | ID: ibc-198848

ABSTRACT

BACKGROUND: açaí is the fruit of the palm tree Euterpe oleracea Martius, which is native to the Amazon region. This fruit has been extensively studied due to its potential effects on human health. Studies have also evaluated the potential effect of açaí on the inflammatory response, but there are still few studies that have assessed this property in humans. OBJECTIVE: in this study we aimed to evaluate the effects of 200 g of açaí pulp consumption per day during four weeks on a rich panel of inflammatory biomarkers. METHODS: a prospective nutritional intervention study was conducted on forty apparently healthy women who consumed 200 g of açaí pulp per day for four weeks. A panel of serum inflammatory markers were evaluated before and after the nutritional intervention, namely, cell adhesion molecules (ICAM-1, IVAM-1, P-selectin, MCP-1, and fractalkine), interleukins (IL-1β, IL-6, IL-8, IL-10, and IL-17) and adipokines (adiponectin, leptin, visfatin, and adipsin). The data were analyzed using paired Student's t-test to evaluate the effect of the intervention using PASW Statistics, version 18.0, and a p-value of < 0.05 was considered significant. RESULTS: four weeks of açaí pulp consumption decreased p-selectin, leptin, and visfatin concentrations in the serum of the participating women. CONCLUSION: these results show that consumption of açaí pulp was able to modulate important biomarkers of the inflammatory process in apparently healthy women


INTRODUCCIÓN: el açaí es el fruto de la palmera Euterpe oleracea Martius, originaria de la región amazónica. Esta fruta ha sido ampliamente estudiada debido a sus posibles efectos sobre la salud humana. Los estudios también han evaluado el efecto potencial del açaí sobre la respuesta inflamatoria, pero todavía hay pocos estudios que hayan evaluado esta propiedad en seres humanos. OBJETIVO: en este estudio, nuestro objetivo ha sido evaluar los efectos del consumo de 200 g de pulpa de açaí por día durante cuatro semanas sobre un rico panel de biomarcadores inflamatorios. MÉTODOS: se ha realizado un estudio prospectivo de intervención nutricional en el que cuarenta mujeres aparentemente sanas han consumido 200 g de pulpa de açaí al día durante cuatro semanas. Se ha evaluado un panel de marcadores inflamatorios séricos antes y después de la intervención nutricional, a saber, moléculas de adhesión celular (ICAM-1, IVAM-1, P-selectina, MCP-1 y fractalquina), interleucinas (IL-1β, IL-6, IL-8, IL-10 e IL-17) y adipocinas (adiponectina, leptina, visfatina y adipsina). Los datos han sido analizados mediante la prueba de la t de Student pareada para evaluar el efecto de la intervención mediante el PASW Statistics, versión 18.0, y todo valor de p < 0,05 se consideró significativo. RESULTADOS: después de cuatro semanas de consumo de pulpa de açaí disminuyeron las concentraciones de p-selectina, leptina y visfatina en el suero de las mujeres participantes. CONCLUSIÓN: estos resultados muestran que el consumo de pulpa de açaí ha sido capaz de modular importantes biomarcadores del proceso inflamatorio en mujeres aparentemente sanas


Subject(s)
Humans , Female , Adolescent , Young Adult , Adult , Eating , Euterpe , Dietetics , P-Selectin/metabolism , Leptin/metabolism , Nicotinamide Phosphoribosyltransferase/administration & dosage , Cell Adhesion , Biomarkers , Prospective Studies , Interleukins/blood , Anthropometry , Adipokines
3.
Nutr Hosp ; 38(1): 121-127, 2021 Feb 23.
Article in English | MEDLINE | ID: mdl-33319583

ABSTRACT

INTRODUCTION: Background: açaí is the fruit of the palm tree Euterpe oleracea Martius, which is native to the Amazon region. This fruit has been extensively studied due to its potential effects on human health. Studies have also evaluated the potential effect of açaí on the inflammatory response, but there are still few studies that have assessed this property in humans. Objective: in this study we aimed to evaluate the effects of 200 g of açaí pulp consumption per day during four weeks on a rich panel of inflammatory biomarkers. Methods: a prospective nutritional intervention study was conducted on forty apparently healthy women who consumed 200 g of açaí pulp per day for four weeks. A panel of serum inflammatory markers were evaluated before and after the nutritional intervention, namely, cell adhesion molecules (ICAM-1, IVAM-1, P-selectin, MCP-1, and fractalkine), interleukins (IL-1ß, IL-6, IL-8, IL-10, and IL-17) and adipokines (adiponectin, leptin, visfatin, and adipsin). The data were analyzed using paired Student's t-test to evaluate the effect of the intervention using PASW Statistics, version 17.0, and a p-value of < 0.05 was considered significant. Results: four weeks of açaí pulp consumption decreased p-selectin, leptin, and visfatin concentrations in the serum of the participating women. Conclusion: these results show that consumption of açaí pulp was able to modulate important biomarkers of the inflammatory process in apparently healthy women.


INTRODUCCIÓN: Introducción: el açaí es el fruto de la palmera Euterpe oleracea Martius, originaria de la región amazónica. Esta fruta ha sido ampliamente estudiada debido a sus posibles efectos sobre la salud humana. Los estudios también han evaluado el efecto potencial del açaí sobre la respuesta inflamatoria, pero todavía hay pocos estudios que hayan evaluado esta propiedad en seres humanos. Objetivo: en este estudio, nuestro objetivo ha sido evaluar los efectos del consumo de 200 g de pulpa de açaí por día durante cuatro semanas sobre un rico panel de biomarcadores inflamatorios. Métodos: se ha realizado un estudio prospectivo de intervención nutricional en el que cuarenta mujeres aparentemente sanas han consumido 200 g de pulpa de açaí al día durante cuatro semanas. Se ha evaluado un panel de marcadores inflamatorios séricos antes y después de la intervención nutricional, a saber, moléculas de adhesión celular (ICAM-1, IVAM-1, P-selectina, MCP-1 y fractalquina), interleucinas (IL-1ß, IL-6, IL-8, IL-10 e IL-17) y adipocinas (adiponectina, leptina, visfatina y adipsina). Los datos han sido analizados mediante la prueba de la t de Student pareada para evaluar el efecto de la intervención mediante el PASW Statistics, versión 17.0, y todo valor de p < 0,05 se consideró significativo. Resultados: después de cuatro semanas de consumo de pulpa de açaí disminuyeron las concentraciones de p-selectina, leptina y visfatina en el suero de las mujeres participantes. Conclusión: estos resultados muestran que el consumo de pulpa de açaí ha sido capaz de modular importantes biomarcadores del proceso inflamatorio en mujeres aparentemente sanas.


Subject(s)
Cytokines/blood , Euterpe , Fruit , Leptin/blood , Nicotinamide Phosphoribosyltransferase/blood , P-Selectin/blood , Adiponectin/blood , Biomarkers/blood , Cell Adhesion Molecules/blood , Complement Factor D/analysis , Female , Humans , Interleukins/blood , Prospective Studies
4.
Nutr Cancer ; 73(3): 523-533, 2021.
Article in English | MEDLINE | ID: mdl-32367766

ABSTRACT

Intestinal mucositis (IM) caused by antineoplastic chemotherapy is characterized by an important inflammatory process, which may compromise ongoing treatment. Our study aimed to investigate the effect of Açaí (Euterpe oleracea Martius) on the antioxidant response in BALB/c mice pretreated with Açaí pulp (200 g/kg) for 14 day. A group of animals receiving a single intraperitoneal injection of 5-FU (200 mg/kg) were euthanized on day three (D3) or seven (D7) after administration, the distal jejunum was isolated for the analyses of histology, superoxide dismutase (SOD) and catalase (CAT) enzyme activities, and concentration of total sulfhydryl groups (GSH). Seven days after induction, the intake of Açaí by the IM group almost completely regenerated tissue histology. Notably, SOD activity decreased in the MUC + Açaí group (D3). CAT activity reduced on D3 and D7 in the IM groups and Açaí treatment groups, respectively. No change was observed in the total GSH concentration at the tissue level. Our results demonstrated the protective effect of Açaí pulp components on intestinal damage induced by 5-FU, as well as the ability to control the response to oxidative stress, in order to mobilize defense pathways and promote tissue repair.


Subject(s)
Euterpe , Mucositis , Animals , Antioxidants , Fluorouracil , Jejunum , Mice , Mice, Inbred BALB C , Mucositis/chemically induced , Mucositis/drug therapy , Plant Extracts/pharmacology
5.
J Nutr Biochem ; 57: 238-245, 2018 07.
Article in English | MEDLINE | ID: mdl-29800810

ABSTRACT

Dietary supplementation with conjugated linoleic acid (CLA) has been proposed for weight management and to prevent gut inflammation. However, some animal studies suggest that supplementation with CLA leads to the development of nonalcoholic fatty liver disease. The aims of this study were to test the efficiency of CLA in preventing dextran sulfate sodium (DSS)-induced colitis, to analyze the effects of CLA in the liver function, and to access putative liver alterations upon CLA supplementation during colitis. So, C57BL/6 mice were supplemented for 3 weeks with either control diet (AIN-G) or 1% CLA-supplemented diet. CLA content in the diet and in the liver of mice fed CLA containing diet were accessed by gas chromatography. On the first day of the third week of dietary treatment, mice received ad libitum a 1.5%-2.5% DSS solution for 7 days. Disease activity index score was evaluated; colon and liver samples were stained by hematoxylin and eosin for histopathology analysis and lamina propria cells were extracted to access the profile of innate cell infiltrate. Metabolic alterations before and after colitis induction were accessed by an open calorimetric circuit. Serum glucose, cholesterol, triglycerides and alanine aminotransaminase were measured; the content of fat in liver and feces was also accessed. CLA prevented weight loss, histopathologic and macroscopic signs of colitis, and inflammatory infiltration. Mice fed CLA-supplemented without colitis induction diet developed steatosis, which was prevented in mice with colitis probably due to the higher lipid consumption as energy during gut inflammation. This result suggests that CLA is safe for use during gut inflammation but not at steady-state conditions.


Subject(s)
Colitis/diet therapy , Linoleic Acids, Conjugated/pharmacology , Non-alcoholic Fatty Liver Disease/chemically induced , Alanine Transaminase/blood , Animals , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Colitis/chemically induced , Colitis/prevention & control , Colon/drug effects , Colon/immunology , Colon/pathology , Dextran Sulfate/toxicity , Dietary Supplements , Female , Immunity, Innate/drug effects , Immunity, Innate/physiology , Linoleic Acid/metabolism , Linoleic Acids, Conjugated/adverse effects , Liver/cytology , Liver/drug effects , Liver/metabolism , Mice, Inbred C57BL
6.
Public Health Nutr ; 21(8): 1546-1553, 2018 06.
Article in English | MEDLINE | ID: mdl-29455688

ABSTRACT

OBJECTIVE: In the present study we investigated gender-specific associations of low birth weight (LBW) and shorter relative leg length with metabolic syndrome (MetS) after adjusting for sociodemographic characteristics and health-related behaviours. We also investigated whether these associations are independent of age at menarche and BMI at 20 years old. DESIGN: Cross-sectional analysis. SUBJECTS: Baseline data from 12 602 participants (35-74 years) of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), 2008-2010. SETTING: MetS was defined according to the revised National Cholesterol Education Program Adult Treatment Panel III guidelines. LBW (<2·5 kg) and age- and sex-standardized relative leg length (high, medium and low) were the explanatory variables studied. The strength of the associations between the explanatory variables and MetS was estimated by Poisson regression with robust variance. RESULTS: MetS prevalence was 34·2 %; it was more prevalent in men (36·8 %) than in women (32·2 %). In multivariate analysis, LBW was associated (prevalence ratio; 95 % CI) with MetS only in women (1·28; 1·24, 1·45). Shorter leg length was associated with MetS in both men (1·21; 1·09, 1·35 and 1·46; 1·29, 1·65 for low and medium lengths, respectively) and women (1·12; 1·00, 1·25 and 1·40; 1·22, 1·59 for low and medium lengths, respectively). Additional adjustments for age at menarche and BMI at 20 years old did not change the associations. CONCLUSIONS: Poor nutritional status as estimated by LBW and lower leg length in childhood was associated with a higher prevalence of MetS, although LBW was a significant factor only among women.


Subject(s)
Birth Weight/physiology , Metabolic Syndrome/epidemiology , Nutritional Status/physiology , Adult , Aged , Body Size/physiology , Brazil/epidemiology , Cross-Sectional Studies , Female , Humans , Male , Middle Aged
7.
Nutr. clín. diet. hosp ; 37(4): 40-47, 2017. graf, tab
Article in Portuguese | IBECS | ID: ibc-171046

ABSTRACT

Introdução: Pacientes internados em unidade de terapia intensiva (UTI) são mais propensos às perdas calórico-proteicas durante sua permanência, o que interfere significativamente na recuperação e consequentemente demora para a alta hospitalar, bem como aumento da taxa de mortalidade. Para isso, a literatura dispõe de vários métodos e ferramentas de avaliação do estado nutricional para identificar pacientes em risco nutricional ou desnutridos. Objetivo: Avaliar o perfil nutricional de indivíduos internados em uma unidade de terapia intensiva a partir de métodos objetivos e subjetivos. Metodologia: Estudo transversal com 328 pacientes admitidos na UTI. Para avaliar o estado nutricional, foram obtidos dados objetivos antropométricos como índice de massa corporal (IMC), dobra cutânea tricipital (DCT), circunferência do braço (CB) e muscular do braço (CMB) e dados subjetivos como avaliação subjetiva global (ANSG), avaliação do risco nutricional 2002 (NRS 2002) e do índice do risco nutricional (IRN). Resultados: Dos 328 pacientes avaliados, 55,5% eram do sexo masculino, com idade média de 61,4 ± 18,8 anos. Houve maior frequência de pacientes acima de 60 anos (62,5%) e de pacientes com acidente vascular encefálico (14,3%). No método objetivo, foi observado que 46,0% e 65,2% dos pacientes estavam eutróficos pelo IMC e CMB, respectivamente e 56,4% e 38,2% desnutridos pela DCT e pela CB. Os métodos subjetivos, identificaram elevada frequência de risco nutricional e desnutrição pela NRS 2002 e pelo IRN. Já na ANSG, metade dos pacientes estavam bem nutridos. Houve maior semelhança entre os diagnósticos da ANSG com as medidas antropométricas. Conclusão: A utilização dos diferentes métodos objetivos e subjetivos de avaliação nutricional são capazes de identificar o perfil nutricional dos pacientes internados em UTI, sendo importante aplicá-los concomitantemente pois contribui complementando informações para um melhor e real diagnóstico nutricional, uma vez que, para esses pacientes considerados críticos, não existem métodos considerados “padrão ouro” para avaliar o estado nutricional em situação de terapia intensiva (AU)


Introduction: Patients admitted to the intensive care unit (ICU) are more prone to caloric-protein losses during their stay, which significantly impairs recovery and consequently delays in hospital discharge, as well as an increase in the mortality rate. For this, the literature has several methods and tools for assessing nutritional status to identify patients at nutritional or malnourished risk. Objective: To evaluate the nutritional profile of individuals hospitalized in an intensive care unit based on objective and subjective methods. Methodology: A cross-sectional study with 328 patients admitted to the ICU. To evaluate the nutritional status, we obtained anthropometric objectives such as body mass index (BMI), tricipital skinfold (DCT), arm circumference (CB) and arm muscle (CMB) and subjective data such as global subjective assessment (ANSG), Nutritional risk assessment 2002 (NRS 2002) and nutritional risk index (NRI). Results: Of the 328 patients evaluated, 55.5% were males, with a mean age of 61.4 ± 18.8 years. There was a higher frequency of patients over 60 years (62.5%) and patients with cerebrovascular accident (14.3%). In the objective method, it was observed that 46.0% and 65.2% of the patients were eutrophic by BMI and CMB, respectively, and 56.4% and 38.2% were malnourished by DCT and CB. The subjective methods identified a high frequency of nutritional risk and malnutrition by NRS 2002 and IRN. At ANSG, half of the patients were well nourished. Conclusions: The use of different objective and subjective methods of nutritional assessment are able to identify the nutritional profile of patients hospitalized in ICU, and it is important to apply them concomitantly as it contributes by complementing information to a Better and real nutritional diagnosis, since, for these patients considered critical, there are no methods considered “gold standard” to evaluate nutritional status in an intensive care situation (AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Critical Care/methods , Nutrition Assessment , Anthropometry/methods , Malnutrition/diet therapy , Nutritional Status , Intensive Care Units , Cross-Sectional Studies/methods
8.
Nutrition ; 32(6): 674-80, 2016 Jun.
Article in English | MEDLINE | ID: mdl-26883870

ABSTRACT

OBJECTIVES: The aim of the present study was to evaluate the effect of açai pulp (Euterpe oleracea Martius) intake on the prevention of oxidative damage by measuring the activity of antioxidant enzymes and biomarkers of protein oxidation in women. METHODS: A nutritional intervention study was conducted with thirty-five healthy women who were asked to consume 200 g/d of açai pulp for 4 wk. Blood samples were collected, and blood pressure and anthropometric parameters were measured before and after the experimental period. Antioxidant enzymes, superoxide dismutase, catalase, glutathione, production of reactive oxygen species, and total antioxidant capacity were evaluated in polymorphonuclear cells. Serum concentration of protein carbonyl and sulfhydryl groups were also determined. RESULTS: The açai intake increased catalase activity, total antioxidant capacity, and reduced the production of reactive oxygen species. Furthermore, it reduced serum concentration of protein carbonyl and increased total serum sulfhydryl groups. CONCLUSIONS: These results show the antioxidant benefit of dietary açai for the healthy women included in the present study, and may increase understanding of the beneficial health properties of this fruit.


Subject(s)
Antioxidants/pharmacology , Diet/methods , Euterpe , Fruit , Plant Extracts/blood , Adolescent , Adult , Biomarkers/blood , Female , Humans , Prospective Studies , Reference Values , Superoxide Dismutase/blood , Young Adult
9.
Nutr. hosp ; 32(2): 931-945, ago. 2015. tab, ilus
Article in English | IBECS | ID: ibc-140034

ABSTRACT

Introduction: obesity, characterized by adiposity excess, is associated with endothelial dysfunction and possible inflammatory state with release of cytokines that determine endothelial function and can trigger chronic diseases. The dietary pattern are associated with the synthesis these cytokines. Fruits as the acai, which is rich in flavonoids, have a direct and beneficial effect on the control of this inflammatory process through the exercised antioxidant capacity. Objective: to evaluate the effect of acai pulp consumption on the inflammatory markers, anthropometric measurements, body composition, biochemical and dietary parameters in healthy women. Methods: forty women, were divided in 25 eutrophic and 15 with overweight. They intaked 200 g of acai pulp during 4 weeks. Anthropometric measurements, body composition, inflammatory markers, biochemical data, dietary intake and dietary antioxidants capacity were evaluated before and after the intervention. Results and discussion: after the intervention, there was significant increase of EGF (p=0.021) and PAI- 1(p=0.011) in overweight women. Moreover, there was increase in body weight (p=0.031), body mass index (p=0.028), percentage of truncal fat (p=0.003) and triceps skinfold thickness (p=0.046) in eutrophic women. However, the skinfold thickness (p=0.018) and total body fat (p=0.016) decreased in overweight women. There was reduction of total protein (p=0.049) due to the globulin reduction (p=0.005), but the nutritional status was maintained in eutrophic group. Conclusion: the intake of 200g acai pulp, modulated the EGF and PAI-1 expression, possibly by modulation of acai on the parameters of body composition, dietary, clinical, biochemical and inflammatory, led to a redistribution and resizing of body fat of the trunk area, and presumably increased visceral fat (AU)


Introducción: la obesidad, que se caracteriza por el exceso de adiposidad, se asocia con disfunción endotelial y posible estado inflamatorio con liberación de citoquinas que determinan la función endotelial y pueden desencadenar enfermedades crónicas. El patrón de dieta está asociado con la síntesis de estas citoquinas. Los frutos del acai, que es rico en flavonoides, tienen un efecto directo y positivo en el control de este proceso inflamatorio a través de los ejercicios de la capacidad antioxidante. Objetivo: evaluar el efecto del consumo de pulpa de acai en los marcadores inflamatorios, las medidas antropométricas, la composición corporal y los parámetros bioquímicos y dietéticos en mujeres sanas. Métodos: cuarenta mujeres fueron divididas en 25 eutróficas y 15 con sobrepeso. Se las administró 200 g de pulpa de acai durante 4 semanas. Antes y después de la intervención se evaluaron: medidas antropométricas, composición corporal, marcadores inflamatorios, datos bioquímicos, ingesta dietética y antioxidantes en la dieta. Resultados y discusión: después de la intervención, hubo un aumento significativo de EGF (p=0,021) y PAI-1 (p=0,011) en las mujeres con sobrepeso. Por otra parte, en las mujeres eutróficas hubo aumento del peso corporal (p=0,031), el índice de masa corporal (p=0,028), el porcentaje de grasa del tronco (p=0,003) y el espesor del pliegue cutáneo del tríceps (p=0,046). Sin embargo, el espesor del pliegue cutáneo (p=0,018) y la grasa corporal total (p=0,016) se redujeron en las mujeres con sobrepeso. Hubo una reducción de la proteína total (p=0,049) debida a la disminución de globulina (p=0,005), pero el estado nutricional se mantuvo en el grupo eutrófico. Conclusión: la ingesta de 200 g de pulpa de acai modula el EGF y PAI-1 de expresión, posiblemente por la modulación del acai en los parámetros de la composición corporal, la dieta, clínicos, bioquímicos e inflamatorios, lo que dio lugar a una redistribución y modificación del tamaño de la grasa corporal de la zona del tronco, y, presumiblemente, un aumento de la grasa visceral (AU)


Subject(s)
Adult , Female , Humans , Euterpe/metabolism , Plasminogen/metabolism , Plasminogen/therapeutic use , Plasminogen Activators/therapeutic use , Epidermal Growth Factor/analysis , Epidermal Growth Factor , Healthy Volunteers/statistics & numerical data , Obesity/diet therapy , Phytotherapy/organization & administration , Body Composition/physiology , Anthropometry/methods , Antioxidants/therapeutic use , Inflammation/diet therapy , Inflammation/prevention & control
10.
Br J Nutr ; 113(6): 935-43, 2015 Mar 28.
Article in English | MEDLINE | ID: mdl-25759975

ABSTRACT

The aim of the present study was to investigate the effect of a protein-free diet in the induction of food allergy and oral tolerance in BALB/c mice. The experimental model used was mice that were fed, since weaning up to adulthood, a balanced diet in which all dietary proteins were replaced by amino acid diet (Aa). The absence of dietary proteins did not prevent the development of food allergy to ovalbumin (OVA) in these mice. However, Aa-fed mice produced lower levels of IgE, secretory IgA and cytokines. In addition, when compared with mice from control group, Aa-fed mice had a milder aversive reaction to the allergen measured by consumption of OVA-containing solution and weight loss during food allergy development. In addition, mice that did not have dietary proteins in their diets were less susceptible to induction of oral tolerance. One single oral administration was not enough to suppress specific serum Ig and IgG1 levels in the Aa-fed group, although it was efficient to induce suppression in the control group. The present results indicate that the stimulation by dietary proteins alters both inflammatory reactivity and regulatory immune reactivity in mice probably due to their effect in the maturation of the immune system.


Subject(s)
Diet, Protein-Restricted , Food Hypersensitivity/prevention & control , Immune Tolerance , Immunity, Mucosal , Intestinal Mucosa/immunology , Mouth Mucosa/immunology , Amino Acids/therapeutic use , Animals , Caseins/adverse effects , Caseins/therapeutic use , Cells, Cultured , Cytokines/metabolism , Diet, Protein-Restricted/adverse effects , Female , Food Hypersensitivity/immunology , Food Hypersensitivity/metabolism , Food Hypersensitivity/pathology , Immunoglobulin A, Secretory/analysis , Immunoglobulin A, Secretory/biosynthesis , Immunoglobulin E/analysis , Immunoglobulin E/biosynthesis , Immunoglobulin G/analysis , Immunoglobulin G/biosynthesis , Intestinal Mucosa/metabolism , Intestinal Mucosa/pathology , Lymph Nodes/immunology , Lymph Nodes/metabolism , Lymph Nodes/pathology , Lymphocytes/immunology , Lymphocytes/metabolism , Lymphocytes/pathology , Mice, Inbred BALB C , Mouth Mucosa/metabolism , Weaning , Weight Loss
11.
Rev. baiana saúde pública ; 36(4)out.-dez. 2012. tab
Article in Portuguese | LILACS | ID: lil-689442

ABSTRACT

A anemia falciforme (AF), uma das doenças hematológicas mais difundidas no mundo, apresenta como principal característica seus portadores possuírem uma hemoglobina anormal denominada S (HbS) em suas hemácias. O objetivo deste estudo foi avaliar o perfil antropométrico e dietético de pré-escolares e escolares com AF, considerando seu status socioeconômico, consumo de energia e nutrientes e o índice de desnutrição proteico- -calórico. Este estudo foi do tipo transversal e de natureza quantitativa, realizado no município de Januária (MG), no período de outubro a dezembro de 2010. A coleta de dados foi realizada por meio da aplicação de questionário e avaliação antropométrica. Os resultados mostraram que pais/responsáveis tinham baixa escolaridade e as famílias viviam em situação de pobreza. A maioria das crianças era eutrófica e fazia o número de refeições diárias recomendado, mas a quantidade e qualidade dos alimentos eram inadequadas. Houve déficit expressivo no consumo de micronutrientes devido ao baixo consumo de frutas e verduras. Concluiu-se que a população estudada, predominantemente de baixo nível socioeconômico, apresentava indicadores antropométricos dentro dos limites de eutrofia, no entanto o consumo dietético era inadequado


Patients with the sickle cell disease (SCD), one of the most common blood diseases worldwide, carry an abnormal type of hemoglobin called S (HbS). This study evaluated the anthropometrical and dietary patterns of preschool and school-aged children with SCD, considering their socioeconomic status, energy and nutrient intake and the index of protein-calorie malnutrition. This is a quantitative, cross-sectional study carried out in Januária (MG), Brazil from October to December 2010. Data collection was conducted through questionnaire application and anthropometric measurements. The results showed that the parents/guardians had low education and the families lived in poverty. Most children had normal weight and height and received the recommended number of meals per day, but food amount and quality were inadequate. An expressive deficit in micronutrient intake was detected likely because of low fruit and vegetable consumption. In conclusion, the population studied, most of low socioeconomic status, exhibited anthropometrical indicators within normal weight and height range, but their dietary habits were inadequate.


La Anemia falciforme (AF), una de las enfermedades hematológicas más difundidas en el mundo, sus portadores presentan, como principal característica, una hemoglobina anormal denominada S(HbS) en sus hematíes. Estudio de enfoque transversal y de naturaleza cuantitativa, realizado en el municipio de Januária (MG), en el período octubre-diciembre de 2010. La recolecta de datos fue realizada a través de un cuestionario y evaluación antropométrica. Los resultados mostraron que los padres/responsables tenían baja escolaridad y las familias vivían en situación de pobreza. La mayoría de los niños era eutrófica y la alimentación diaria, en número, estaba dentro de lo recomendado, pero la cantidad y la calidad de la misma era inadecuada. Hubo un déficit expresivo en el consumo de micronutrientes debido al bajo consumo de frutas y verduras. Se concluye que la población estudiada, predominantemente de bajo nivel socioeconómico, presentaba indicadores antropométricos dentro de los límites de eutrofia, sin embargo, el consumo dietético era inadecuado.


Subject(s)
Anemia, Sickle Cell , Child Health , Child Nutrition , Hematologic Diseases
SELECTION OF CITATIONS
SEARCH DETAIL
...