ABSTRACT
La inmunodeficiencia común variable es una de las alteraciones de la inmunidad más frecuentes. Suele manifestarse con infecciones respiratorias de repetición, desde neumonías hasta otitis, y puede asociarse a otras patologías, como bronquiectasias o enfermedades intersticiales. Presentamos el caso de un paciente de 28 años con infecciones respiratorias frecuentes e infiltrados nodulares pulmonares, que fue diagnosticado de inmunodeficiencia común variable y bronquiolitis folicular. La bronquiolitis folicular se asocia, en algunos casos, a inmunodeficiencias y debe realizarse un diagnóstico diferencial con la hiperplasia nodular linfoide, la neumonía intersticial linfocítica y el linfoma BALT de bajo grado(AU)
Common variable immunodeficiency is one of the most frequent immunity alterations. The most common clinical presentation occurs with recurrent respiratory infections, from pneumonia to otitis, and may be associated with other diseases such as bronchiectasis or interstitial lung diseases. We report the case of a 28-year-old patient with frequent respiratory infections and nodular pulmonary infiltrates, who was diagnosed with common variable immunodeficiency and follicular bronchiolitis. In some of the cases, follicular bronchiolitis is associated with immunodeficiencies and should be included in a differential diagnosis with lymphoid nodular hyperplasia, lymphocytic interstitial pneumonia and low-grade BALT lymphoma(AU)
Subject(s)
Humans , Male , Adult , Bronchiolitis/complications , Bronchiolitis/diagnosis , Immunologic Deficiency Syndromes/complications , Pneumonia, Pneumocystis/complications , Lung Diseases, Interstitial/complications , Lung Diseases, Interstitial/diagnosis , Respiratory Tract Infections/complications , Respiratory Tract Infections/diagnosis , Lung Diseases, Interstitial/physiopathology , Lung Diseases, Interstitial , Respiratory Tract Infections/epidemiology , Respiratory Tract Infections/physiopathology , Respiratory Tract Infections , Radiography, Thoracic , Diagnosis, DifferentialABSTRACT
Common variable immunodeficiency is one of the most frequent immunity alterations. The most common clinical presentation occurs with recurrent respiratory infections, from pneumonia to otitis, and may be associated with other diseases such as bronchiectasis or interstitial lung diseases. We report the case of a 28-year-old patient with frequent respiratory infections and nodular pulmonary infiltrates, who was diagnosed with common variable immunodeficiency and follicular bronchiolitis. In some cases, follicular bronchiolitis is associated with immunodeficiencies and should be included in a differential diagnosis with lymphoid nodular hyperplasia, lymphocytic interstitial pneumonia and low-grade BALT lymphoma.
