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Emerg Infect Dis ; 18(3): 473-6, 2012 Mar.
Article in English | MEDLINE | ID: mdl-22377016

ABSTRACT

We analyzed travel-associated clinical isolates of Escherichia coli O104:H4, including 1 from the 2011 German outbreak and 1 from a patient who returned from the Philippines in 2010, by genome sequencing and optical mapping. Despite extensive genomic similarity between these strains, key differences included the distribution of toxin and antimicrobial drug-resistance determinants.


Subject(s)
Disease Outbreaks , Escherichia coli Infections/epidemiology , Shiga-Toxigenic Escherichia coli/isolation & purification , Travel , Aged , Bacterial Proteins/genetics , Canada/epidemiology , Escherichia coli Infections/diagnosis , Escherichia coli Infections/microbiology , Genome, Bacterial , Humans , Infant , Male , Sequence Analysis, DNA , Shiga-Toxigenic Escherichia coli/genetics
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