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1.
J Occup Environ Med ; 42(6): 660-9, 2000 Jun.
Article in English | MEDLINE | ID: mdl-10874660

ABSTRACT

This investigation examined surface electromyography as an additional tool in the comprehensive clinical evaluation of patients with chronic low back pain (CLBP). Electromyographic signals from electrodes placed in the lumbar area of 30 CLBP patients and 30 non-pain control subjects were compared. Patients and controls were matched for age, gender, and body mass index. Paired t test showed a statistically significant difference between the two groups. The muscle activity mean values were threefold higher in CLBP patients than in controls (P < 0.00001) in the static testing, and twofold higher in CLBP patients than in controls (P < 0.00001) in the dynamic testing. Our findings indicate that surface electromyography assessment of the paraspinal muscle activity may be a useful objective diagnostic tool in the comprehensive evaluation of CLBP.


Subject(s)
Electromyography/methods , Low Back Pain/diagnosis , Adult , Chronic Disease , Female , Humans , Male , Middle Aged , Pain Measurement , Probability , Reference Values , Sensitivity and Specificity , Severity of Illness Index
2.
Control Clin Trials ; 2(1): 31-49, 1981 May.
Article in English | MEDLINE | ID: mdl-7261638

ABSTRACT

A system has been constructed to evaluate the design, implementation, and analysis of randomized control trials (RCT). The degree of quadruple blinding (the randomization process, the physicians and patients as to therapy, and the physicians as to ongoing results) is considered to be the most important aspect of any trial. The analytic techniques are scored with the same emphasis as is placed on the control of bias in the planning and implementation of the studies. Description of the patient and treatment materials and the measurement of various controls of quality have less weight. An index of quality of a RCT is proposed with its pros and cons. If published papers were to approximate these principles, there would be a marked improvement in the quality of randomized control trials. Finally, a reasonable standard design and conduct of trials will facilitate the interpretation of those with conflicting results and help in making valid combinations of undersized trials.


Subject(s)
Clinical Trials as Topic/standards , Humans , Random Allocation , Research Design
3.
Mt Sinai J Med ; 45(3): 443-4, 1978.
Article in English | MEDLINE | ID: mdl-307662
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