1.
Beijing Da Xue Xue Bao Yi Xue Ban
; 37(1): 94-5, 2005 Feb 18.
Article
in English
| MEDLINE
| ID: mdl-15719052
ABSTRACT
Constitutional full trisomy 21 is a common disorder in which abnormal spermatogenesis has been previously described. However, constitutional mosaic trisomy 21 in an otherwise normal but infertile male has not been explored. We report a case with low level mosaic trisomy 21 in a non-syndrome but azoospermic patient. We also propose that the patient's azoospermia may be related to the constitutional mosaic trisomy 21 and thus resulting in a late onset of testicular failure.