PROTOCOL: The impact of infrastructure on low income consumers' nutritious diet, women's economic empowerment, and gender equality in low-and middle-income countries: An evidence and gap map.

This is the protocol for an evidence and gap map. The objectives are as follows: this evidence and gap map (EGM) aims to identify, map, and provide an overview of the existing evidence and gaps on the impact of different types of physical infrastructure on various outcomes of low-income consumers' nutritious diet, women's economic empowerment, and gender equality in low- and middle-income countries. The specific objectives of the EGM are: (1) identify clusters of evidence that offer opportunities for evidence synthesis and (2) identify gaps in evidence where new studies, research, and evaluations are needed.

Access to high-priced medicines in lower-income countries in the WHO European Region

Lower-income countries (LICs) in the WHO European Region generally have poorer health status and more limited resources than higher-income countries. This creates pressing issues when making decisions on financing high-priced medicines. The market access strategies for innovative medicines in LICs usually follow the low-volume, high-price business model, which does not guarantee access for all potentially eligible patients. If the political will to make changes exists, however, several policy tools could be used that may improve patient access to these medicines. This technical report describes specific constraints of LICs related to public financing of high-priced medicines, and summarizes policy considerations to improve access to high-priced medicines in LICs in three areas, including price-control mechanisms, tools to increase the negotiation power of health-care payers and tools to facilitate appropriate prescribing.