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1.
Emerg Infect Dis ; 11(6): 928-30, 2005 Jun.
Article in English | MEDLINE | ID: mdl-15963289

ABSTRACT

Community-associated methicillin-resistant Staphylococcus aureus (MRSA) is the most common pathogen among patients with skin and soft tissue infections seeking treatment at a Los Angeles (USA) area emergency department. The proportion caused by MRSA increased from 29% in 2001 to 2002 to 64% in 2003 to 2004. No clinical or historical features reliably predict MRSA etiology.


Subject(s)
Community-Acquired Infections/epidemiology , Emergency Service, Hospital , Methicillin Resistance , Staphylococcal Skin Infections/epidemiology , Staphylococcus aureus/drug effects , Adult , Anti-Bacterial Agents/pharmacology , Community-Acquired Infections/microbiology , Female , Humans , Los Angeles , Male , Microbial Sensitivity Tests , Middle Aged , Prevalence , Staphylococcal Skin Infections/microbiology
2.
J Am Chem Soc ; 125(24): 7156-7, 2003 Jun 18.
Article in English | MEDLINE | ID: mdl-12797771

ABSTRACT

Diethylaniline-terminated oligo(phenyl-ethynyl)-thiol (DEA-OPE-SH) wires on Au-bead electrodes facilitate electron tunneling to and from the deeply buried topaquinone (TPQ) cofactor in Arthrobacter globiformis amine oxidase (AGAO). Reversible cyclic voltammograms were observed when AGAO was adsorbed onto this DEA-OPE-SAu surface: the 2e-/2H+ reduction potential is -140 mV versus SCE.


Subject(s)
Amine Oxidase (Copper-Containing)/chemistry , Arthrobacter/enzymology , Dihydroxyphenylalanine/analogs & derivatives , Gold/chemistry , Amine Oxidase (Copper-Containing)/metabolism , Binding Sites , Dihydroxyphenylalanine/chemistry , Electrochemistry/methods , Electrodes , Models, Molecular , Oxidation-Reduction
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