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Nephrol Ther ; 5(4): 299-301, 2009 Jul.
Article in French | MEDLINE | ID: mdl-19345628

ABSTRACT

Keratitis occurring in renal transplant patients are often severe, with difficult management. We describe the case of a renal transplant patient, 44 year-old man, with history of recurrent herpetic keratitis, which developed an impending corneal perforation. Conjunctival smear showed the presence of amoebic cysts. Anti-amoebic treatment was undertaken in addition with oral aciclovir, and a therapeutic penetrating keratoplasty was performed. An ulceration of the graft occurred within five months. Ocular samples showed the presence of Candida albicans. Despite aggressive antifungal therapy, he required a second therapeutic penetrating keratoplasty for graft perforation. One month later, we noted a recurrence of the ulcer with corneal thinning which evolved to perforation.


Subject(s)
Acyclovir/therapeutic use , Amebiasis/diagnosis , Conjunctiva/pathology , Keratitis, Herpetic/complications , Kidney Transplantation/adverse effects , Retinal Perforations/etiology , Adult , Amebiasis/drug therapy , Animals , Antifungal Agents/therapeutic use , Candida albicans/isolation & purification , Conjunctiva/parasitology , Conjunctiva/surgery , Corneal Transplantation , Humans , Keratitis, Herpetic/surgery , Male , Recurrence , Retinal Perforations/microbiology , Retinal Perforations/parasitology , Retinal Perforations/surgery
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