Spirometric reference values in a large Middle Eastern population.

Ethnic differences in pulmonary function have been frequently reported. The purposes of this study were to derive equations for the prediction of normative spirometry values for a large population of Persians in Isfahan and compare them to reference values from a White Euro-USA population. Spirometry measurements were obtained from 4,341 randomly selected healthy nonsmoker subjects in Isfahan, Iran, utilising American Thoracic Society guidelines and a vigorous quality assurance program. Measured data from 3,213 subjects were analysed using multiple regression techniques to derive prediction equations for spirometric variables; the remaining 1,128 subjects were used as a control group to test the validity of the derived equations. In addition, predicted values were compared with values derived from recently published equations for the USA. Derived prediction equations showed good performance for most spirometric parameters. Compared with USA Whites, adult Persians have minimally lower forced vital capacities, while the values for children are close to USA Whites. In comparison with reference equations based on European or USA populations, local reference values are more biologically and technically suitable for the interpretation of spirometric data from Iranian populations.

Prevalence of irritable bowel syndrome in Shahrekord, Iran.

BACKGROUND: As part of a public health program, we studied the prevalence of irritable bowel syndrome (IBS) as per the Rome II criteria, in Shahrekord community in Iran. METHODS: The study was conducted between August 2002 and March 2003. Of 5492 randomly selected subjects aged 20 years and above (from a total population of approximately 100,000), 4762 (86.7%) successfully completed interviews to fill in a questionnaire that looked into demographic data and various symptoms during the last one year. RESULTS: The 12-month prevalence of IBS was 5.8%. The female-to-male ratio among subjects with IBS was 1.17:1 and was similar to that among those without IBS. Pain relieved by defecation was reported by 427 (9%) subjects, pain associated with change in bowel habit by 340 (7.1%), and pain associated with change in the form of stool by 337 (7.1%) subjects. CONCLUSION: The prevalence of IBS in Shahrekord is lower than that reported from Western developed countries and is closer to that in Asian populations.

Is arm span an accurate measure of height to predict pulmonary function parameters?

UNLABELLED: Interpretation of pulmonary function tests basically depends on prediction of normal values derived from equations using non-deformed body height. In many patients body height can not be accurately measured. The arm-span method has been used for estimating body height, but the normal relationship between body height and arm span is not exact and differs in various ethnic groups and even between two genders of the same race. In order to minimise the error of estimation of non-deformed body height, the normal relationship between body height and arm span was determined for 754 Persian males and 708 females aged 7 to 82 years, all having normal body stature. In accordance with earlier reports, two sets of spirometric parameters derived once from height, sex, age; and again from arm-span, sex, age were statistically different, and overestimated when the measured arm-span was used. The body-height/arm-span relationship is described using linear regression equations; in subgroups aging 20 years or less and those older than 20 in different genders. The results indicate significant sex and age differences in the arm-span/height ratio. Two sets of spirometric parameters predicted by real height, sex, age/and predicted height, sex, age were not statistically different for most of the parameters especially vital capacity. IN CONCLUSION: height estimated from arm span, performs much better than arm span to predict pulmonary function parameters.