1.
Org Lett
; 25(4): 682-687, 2023 Feb 03.
Article
in English
| MEDLINE
| ID: mdl-36656103
ABSTRACT
In this communication, a palladium-catalyzed regio- and stereoselective carbonylation of 2-trifluoromethyl-1,3-enynes to afford multisubstituted conjugated dienes has been realized. This protocol features excellent regio- and exclusive (E)-stereoselectivity and a broad substrate scope with both amines and alcohols as the suitable reaction partners and has shown promising functional group tolerance.