Sex-Related Differences in Patient Characteristics, Risk Factors, and Symptomatology in Older Adults with Pulmonary Embolism: Findings from the SERIOUS-PE Study.

Sex-specific factors are implicated in pulmonary embolism (PE) presentation in young patients, as indicated by increased risk in pregnancy. Whether sex differences exist in PE presentation, comorbidities, and symptomatology in older adults, the age group in which most PEs occur, remains unknown. We identified older adults (aged ≥65 years) with PE in a large international PE registry replete with information about relevant clinical characteristics (RIETE registry, 2001-2021). To provide national data from the United States, we assessed sex differences in clinical characteristics and risk factors of Medicare beneficiaries with PE (2001-2019). The majority of older adults with PE in RIETE (19,294/33,462, 57.7%) and in the Medicare database (551,492/948,823, 58.7%) were women. Compared with men, women with PE less frequently had atherosclerotic diseases, lung disease, cancer, or unprovoked PE, but more frequently had varicose veins, depression, prolonged immobility, or history of hormonal therapy (p < 0.001 for all). Women less often presented with chest pain (37.3 vs. 40.6%) or hemoptysis (2.4 vs. 5.6%) but more often with dyspnea (84.6 vs. 80.9%) (p < 0.001 for all). Measures of clot burden, PE risk stratification, and use of imaging modalities were comparable between women and men. PE is more common in elderly women than in men. Cancer and cardiovascular disease are more common in men, whereas transient provoking factors including trauma, immobility, or hormone therapy are more common in elderly women with PE. Whether such differences correlate with disparities in treatment or differences in short- or long-term clinical outcomes warrants further investigation.

Epidemiological, socio-demographic and clinical features of the early phase of the COVID-19 epidemic in Ecuador

BackgroundThe SARS-CoV-2 virus has spread rapidly around the globe. Nevertheless, there is limited information describing the characteristics and outcomes of COVID-19 patients in Latin America. MethodsWe conducted a cross-sectional analysis of 9,468 confirmed COVID-19 cases reported in Ecuador. We calculated overall incidence, mortality, case fatality rates, disability adjusted life years, attack and crude mortality rates, as well as relative risk and relative odds of death, adjusted for age, sex and presence of comorbidities. ResultsA total of 9,468 positive COVID-19 cases and 474 deaths were included in the analysis. Men accounted for 55.4% (n = 5, 247) of cases and women for 44.6% (n = 4, 221). We found the presence of comorbidities, being male and older than 65 years were important determinants of mortality. Coastal regions were most affected by COVID-19, with higher mortality rates than the highlands. Fatigue was reported in 53.2% of the patients, followed by headache (43%), dry cough (41.7%), ageusia (37.1%) and anosmia (36.1%). ConclusionWe present the first analysis of the burden of COVID-19 in Ecuador. Our findings show that men are at higher risk of dying from COVID-19 than women, and risk increases with age and the presence of comorbidities. We also found that blue-collar workers and the unemployed are at greater risk of dying. These early observations offer clinical insights for the medical community to help improve patient care and for public health officials to strengthen Ecuadors response to the outbreak.

Aspectos corporales y sociales a tener en cuenta en una educación inclusiva / Aspectos corporais e sociais a serem considerados numa educação inclusiva / Bodily and social aspects to be considered in inclusive education

La danza integrada, dentro de las artes escénicas inclusivas, encierra una serie de singularidades que son extrapolables a la educación. Esta experiencia es una investigación-acción en la que se pretende conocer cuáles son las herramientas que utiliza el profesorado de Educación Infantil para optimizar la convivencia en el aula, así como su relación con los aspectos corporales y sociales de una educación inclusiva. Las conclusiones se han extraído de la realización de grupos de discusión con profesores en cuatro colegios públicos andaluces. Paralelamente, se ha diseñado un programa de intervención del que se incluye una de las unidades didácticas; en ella se puede observar cómo se plasman en un ámbito educativo los aspectos citados

A dança integrada, dentro das artes cênicas inclusivas, contém uma série de singularidades que podem ser extrapoladas para a educação. Esta experiência é uma pesquisa-ação que se destina a saber quais são as ferramentas utilizadas pelos professores da educação infantil para otimizar a convivência na sala de aula, bem como a relação destes com os aspectos corporais e sociais da uma educação inclusiva. As conclusões foram extraídas de grupos de discussão com professores em quatro escolas públicas da Andaluzia. Paralelamente, foi projetado um programa de intervenção, incluindo uma das unidades de ensino, na qual é possível observar como os aspectos mencionados se refletem num ambiente educacional.

Within Inclusive Performing Arts, integrated dance encompasses a series of singularities which can be transposed to Education. This experience is an action-research study aimed at finding the tools applied by teachers in Early Childhood Education to optimize school life as well as the relationship between these tools and inclusive education's bodily and social aspects. The findings are derived from discussion groups in four state schools in Andalusia. In parallel, an intervention program has been designed, including an educational unit where we can observe how bodily and social aspects are reflected in an educational environment