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1.
Article in English | MEDLINE | ID: mdl-21491264

ABSTRACT

UNLABELLED: The aim of this study was to investigate the stress distribution generated in a veneer restoration of an upper central incisor compared to intact teeth using the finite element analysis after applying a lingual buccal loading at the incisal edge. METHODS: Two models were developed: one model contained enamel, dentine, cementum, periodontal ligament, cortical and trabecullar bones, and the other model was a veneer restoration; both models were developed using MSC/Nastran software (MacNeal-Schwendler Corporation, Los Angeles, CA, USA) as the pre- and post-processor. A 10-N load was applied at the incisal edge from the lingual to the buccal side to simulate oral conditions in this area (protrusion). RESULTS: Von Mises stresses were then analysed for three different regions: A-B (enamel elements under the veneer or second enamel layer), A'-B' (buccal enamel and/or veneer element layer) and C-D (lingual enamel elements layer). A higher stress mode was observed for both models at the lingual cervical region. CONCLUSIONS: The presence of a veneer restoration on the incisors is a good alternative to mimic the behaviour of enamel under protrusion loading conditions. The use of veneers to replace enamel during rehabilitations is recommended.


Subject(s)
Dental Porcelain/chemistry , Dental Stress Analysis/methods , Dental Veneers , Incisor/physiology , Models, Biological , Bite Force , Computer Simulation , Finite Element Analysis , Humans , Incisor/surgery , Stress, Mechanical
2.
Caries Res ; 43(2): 92-6, 2009.
Article in English | MEDLINE | ID: mdl-19321985

ABSTRACT

The purpose of this study was to evaluate the effect of chlorhexidine on the proteolytic activity of carious coronal and root dentin collected from patients. Sound dentin from freshly extracted human teeth was used as a control. Dentin fragments were mixed with a synthetic substrate for proteolytic enzymes (N-benzoyl-DL-arginine-naphthylamide--BANA) and the suspensions mixed with either 0.12% chlorhexidine digluconate or distilled water. These mixtures were incubated for 18 h at 37 degrees C, color was developed by the addition of 0.1% Fast Garnet and their optical density was recorded spectrophotometrically. BANA hydrolysis measured by the optical density of incubated specimens was detected in all tested groups, but was significantly higher for carious than for sound dentin (p < 0.05). The proteolytic activity was reduced for carious coronal and root dentin by chlorhexidine (p < 0.05; 50 and 30%, respectively). Chlorhexidine also reduced the proteolytic activity in sound root dentin (p < 0.05; 20%). Conversely, changes in the proteolytic activity of sound coronal dentin were not observed in the presence of chlorhexidine. The reduction in proteolytic activity by chlorhexidine was significantly higher in carious coronal dentin than in carious root dentin (p < 0.05). In conclusion, part of the effect of chlorhexidine in controlling caries progression in humans may be due to a decrease in the proteolytic activity of carious coronal and root dentin. Because of the prolonged incubation time in the present study, similar results may be obtained clinically with prolonged dentin exposure to chlorhexidine, e.g. chlorhexidine-containing varnishes.


Subject(s)
Anti-Infective Agents, Local/therapeutic use , Chlorhexidine/analogs & derivatives , Dental Caries/enzymology , Dentin/drug effects , Protease Inhibitors/therapeutic use , Tooth Crown/drug effects , Tooth Root/drug effects , Adult , Benzoylarginine-2-Naphthylamide , Chlorhexidine/therapeutic use , Coloring Agents , Dentin/enzymology , Female , Humans , Male , Optical Phenomena , Spectrophotometry , Temperature , Time Factors , Tooth Crown/enzymology , Tooth Root/enzymology
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