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1.
J Med Life ; 8(4): 552-62, 2015.
Article in English | MEDLINE | ID: mdl-26664489

ABSTRACT

The incidence and mortality rate of endometrial cancer has been registering an increasing trend both in Romania and in the whole world. The paper's aim is to analyze the diagnostic approach of endometrial pathology in the University Emergency Hospital Bucharest, on a four years period. The medium age of the patients was of 50.51 ± 10.924 years, and the median age was of 48 years. The youngest patient suffering from endometrial cancer was of 30 years. Dilation and uterine curettage represent the main method used in the performance of endometrial biopsy, based on which the certitude etiologic histopathologic diagnosis was established in 68.4% of the patients with endometrial pathology. Hyperplasias represented half of the pathology (54.9%), most of them being without atypias. Endometrial carcinoma was identified in 19% of the patients. The diagnosis of the disease in IA stage represents 5.5% of the total endometrial cases and the diagnosis of the disease in the stage of its limitation to the uterus (stage IA, IB and IC) was of 64.2%. The endometrioid adenocarcinoma represents the most encountered histopathological form and the degree of tumor differentiation established for 68,15% of the cases was predominantly 1 and 2 (88%). The main symptom, which determines the patients' decision to go to the physician, is the abnormal uterine bleeding. 66% of the cases of endometrial cancer in the stage of the disease limited to the uterus are diagnosed in Romania based on the abnormal uterine bleeding. However, 34% of the cases are diagnosed in advanced stages, presenting a significantly low life expectancy.


Subject(s)
Endometrial Neoplasms/pathology , Endometrium/pathology , Adult , Age Distribution , Aged , Aged, 80 and over , Biopsy , Carcinoma, Endometrioid/pathology , Cell Differentiation , Endometrial Neoplasms/diagnosis , Female , Humans , Hyperplasia , Incidence , Middle Aged , Neoplasm Staging , Polyps/pathology , Romania , Time Factors , Uterine Neoplasms/pathology , Young Adult
2.
J Med Life ; 7(2): 165-71, 2014 Jun 15.
Article in English | MEDLINE | ID: mdl-25408721

ABSTRACT

Reduced fetal growth is seen in about 10% of the pregnancies but only a minority has a pathological background and is known as intrauterine growth restriction or fetal growth restriction (IUGR / FGR). Increased fetal and neonatal mortality and morbidity as well as adult pathologic conditions are often associated to IUGR. Risk factors for IUGR are easy to assess but have poor predictive value. For the diagnostic purpose, biochemical serum markers, ultrasound and Doppler study of uterine and spiral arteries, placental volume and vascularization, first trimester growth pattern are object of assessment today. Modern evaluations propose combined algorithms using these strategies, all with the goal of a better prediction of risk pregnancies.


Subject(s)
Algorithms , Biomarkers/blood , Fetal Development/physiology , Fetal Growth Retardation/diagnosis , Fetal Growth Retardation/epidemiology , Placenta/anatomy & histology , Adult , Female , Humans , Placenta/blood supply , Predictive Value of Tests , Pregnancy , Risk Factors , Ultrasonography, Doppler/methods
3.
Orthopedics ; 7(5): 853-9, 1984 May 01.
Article in English | MEDLINE | ID: mdl-24823039

ABSTRACT

Eighty-seven comminuted Colles' fractures of the Frykman III-VIII variety have been treated with the Medium-C-Hoffmann® external fixator, as an alternative to pins in plaster management, over a three-year period, with an average length of followup of 19 months. A standard technique had been used. The results were assessed on the basis of subjective, objective, and roentgenographic findings. The overall goal of a painless wrist with excellent motion, good strength, and satisfactory cosmesis appears to have been achieved by this method of management.

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