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1.
Anticancer Res ; 38(1): 423-426, 2018 01.
Article in English | MEDLINE | ID: mdl-29277804

ABSTRACT

Gestational choriocarcinomas are very rare malignancies, with only few cases being reported so far. Moreover, the presence of pelvic recurrences after surgically-treated gestational choriocarcinomas is even scarcer situations. We present the case of a 19-year-old patient who was initially submitted to surgery with preoperative diagnosis of ectopic pregnancy. At that moment a left salpingectomy was performed, and the histopathological studies revealed the presence of a left tubal gestational choriocarcinoma. The patient was submitted to adjuvant chemotherapy with methotrexate and dactinomycin. However, six months later she was diagnosed with a pelvic recurrence so she was resubmitted to surgery, debulking to no residual disease being successfully performed. The histopathological studies confirmed the presence of a recurrent tumor with gestational choriocarcinoma structure.


Subject(s)
Choriocarcinoma/surgery , Cytoreduction Surgical Procedures/methods , Fallopian Tube Neoplasms/surgery , Gestational Trophoblastic Disease/surgery , Pregnancy Complications, Neoplastic/surgery , Salpingectomy , Adult , Antibiotics, Antineoplastic/therapeutic use , Antimetabolites, Antineoplastic/therapeutic use , Choriocarcinoma/drug therapy , Dactinomycin/therapeutic use , Female , Humans , Methotrexate/therapeutic use , Neoplasm Recurrence, Local , Pregnancy , Pregnancy, Ectopic/diagnosis , Young Adult
2.
Anticancer Res ; 37(5): 2615-2618, 2017 05.
Article in English | MEDLINE | ID: mdl-28476835

ABSTRACT

BACKGROUND/AIM: Solitary metastases after surgically-treated cervical cancer are a rare entity, with only few cases described so far. PATIENT AND METHODS: We present the case of a 31-year-old patient diagnosed with a tumoral splenic lesion at 18 months after surgically-treated cervical cancer. RESULTS: The patient was submitted to surgery, with a splenectomy being performed. The histopathological studies confirmed the presence of a squamous cell cervical cancer splenic metastasis. At one year follow-up after splenectomy, the patient is free of any recurrent disease. CONCLUSION: Solitary splenic metastases after surgically-treated cervical cancer are rarely seen; however, this diagnostic should not be omitted whenever a medical history of cervical cancer is present.


Subject(s)
Splenic Neoplasms/secondary , Uterine Cervical Neoplasms/pathology , Adult , Female , Humans , Splenectomy , Splenic Neoplasms/surgery , Uterine Cervical Neoplasms/surgery
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