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2.
Curr Diab Rep ; 19(12): 162, 2019 12 16.
Article in English | MEDLINE | ID: mdl-31845115

ABSTRACT

PURPOSE OF REVIEW: The DALI (vitamin D and lifestyle intervention in the prevention of gestational diabetes mellitus (GDM)) study aimed to prevent GDM with lifestyle interventions or Vitamin D supplementation (1600 IU/day). This review summarizes the learnings from the DALI studies among pregnant women with a BMI ≥ 29 kg/m2. RECENT FINDINGS: Women diagnosed with GDM earlier in pregnancy had a worse metabolic profile than those diagnosed later. A combined physical activity (PA) and healthy eating (HE) lifestyle intervention improved both behaviours, limited gestational weight gain (GWG) and was cost-effective. Although GDM risk was unchanged, neonatal adiposity was reduced due to less sedentary time. Neither PA nor HE alone limited GWG or GDM risk. Fasting glucose was higher with HE only intervention, and lower with Vitamin D supplementation. Our combined intervention did not prevent GDM, but was cost-effective, limited GWG and reduced neonatal adiposity.


Subject(s)
Diabetes, Gestational/prevention & control , Dietary Supplements , Healthy Lifestyle , Obesity/complications , Vitamin D/administration & dosage , Diabetes, Gestational/etiology , Diet, Healthy , Europe , Exercise , Female , Humans , Pregnancy , Pregnancy Outcome , Randomized Controlled Trials as Topic
3.
J Sch Health ; 76(6): 246-9, 2006 Aug.
Article in English | MEDLINE | ID: mdl-16918848

ABSTRACT

Environmental allergens are major triggers for pediatric asthma. While children's greatest exposure to indoor allergens is in the home, other public places where children spend a large amount of time, such as school and day care centers, may also be sources of significant allergen encounters. The purpose of this article is to describe schoolroom allergen levels from 3 different geographic sites obtained from dust samples collected in the fall and in spring. Environmental dust samples were collected from elementary schools in Birmingham (AL), Detroit (MI), and Houston (TX), from 4 room locations, including the cafeteria, library, upper grades, and lower grades. Samples were assayed for dust mite (Dermatophagoides pteronyssinus and Dermatophagoides farinae), cat (Felis domesticus), and cockroach (Blatella germanica 2) allergen levels. Allergen levels varied by geographic location and type of schoolroom. Schoolroom settings differed by the type of flooring (hard and carpet), room characteristics and use (food service, library shelves with books, and general classroom with multiple types of materials [individual desks and different types of furniture]), and the average age of the schoolroom dwellers (younger vs. older children). Dust mite, cat, and cockroach allergens were present in all schoolrooms and all sites at varying levels by season and by type of room. Schools may be important sources of direct allergen exposure and reservoirs that could potentially contribute to allergic sensitization and disease exacerbation in children. Further studies are needed to carefully examine the environmental allergen load in schools and its effect on children.


Subject(s)
Air Pollutants/analysis , Air Pollution, Indoor/analysis , Allergens/analysis , Dust/analysis , Environmental Monitoring/methods , Schools , Alabama , Animals , Antigens, Dermatophagoides/analysis , Arthropod Proteins , Aspartic Acid Endopeptidases/analysis , Cysteine Endopeptidases , Glycoproteins/analysis , Humans , Michigan , Pyroglyphidae , Seasons , Texas , Urban Population
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