ABSTRACT
PURPOSE: To report an uncommon case of multifocal choroiditis as the result of disseminated Cryptococcus neoformans infection in a patient who is HIV-positive. DESIGN: Interventional case report. METHODS: A 27-year-old HIV-positive woman with fever, headache, and vomiting was examined. Lumbar puncture was performed and revealed C neoformans infection. Her condition evolved with sudden bilateral blindness and deafness. Ophthalmologic examination revealed multiple yellowish choroidal lesions in the posterior pole of both eyes. RESULTS: Postmortem examination showed disseminated C neoformans infection. Histologic examination of the eyes confirmed the presence of C neoformans in the choroiditis. CONCLUSION: Multifocal choroiditis in C neoformans infection is a rare ophthalmic manifestation. The recognition of this condition by ophthalmologists can help physicians to diagnose a disseminated and fatal disease.
Subject(s)
Choroiditis/microbiology , Cryptococcosis/etiology , Cryptococcus neoformans/isolation & purification , Eye Infections, Fungal/etiology , AIDS-Related Opportunistic Infections/diagnosis , AIDS-Related Opportunistic Infections/drug therapy , AIDS-Related Opportunistic Infections/microbiology , Adult , Antifungal Agents/therapeutic use , Antiretroviral Therapy, Highly Active , Antiviral Agents/therapeutic use , Blindness/etiology , Cerebrospinal Fluid/microbiology , Choroiditis/diagnosis , Choroiditis/drug therapy , Cryptococcosis/diagnosis , Cryptococcosis/drug therapy , Deafness/etiology , Drug Therapy, Combination , Eye Infections, Fungal/diagnosis , Eye Infections, Fungal/drug therapy , Fatal Outcome , Female , HIV Seropositivity/diagnosis , HIV Seropositivity/drug therapy , HIV Seropositivity/microbiology , Humans , Spinal PunctureABSTRACT
Os autores realizaram uma investigaçao que visou identificar os métodos de prevençao da oftalmia neonatorum nas maternidades de Caxias do Sul, através da aplicaçao de um questionário simples e aberto. Constatou-se, assim, que nas 4 maternidades consultadas a prevençao tem sido realizada mediante o uso de vitelinato de prata a 1 por cento ou 2 por cento (Argyrolr), isoladamente ou em associaçao com o nitrato de prata a 1 por cento. O vitelinato de prata, segundo a literatura especializada e consultada, apresenta baixa eficácia.
