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1.
Sensors (Basel) ; 24(7)2024 Mar 26.
Article in English | MEDLINE | ID: mdl-38610318

ABSTRACT

Sound classification plays a crucial role in enhancing the interpretation, analysis, and use of acoustic data, leading to a wide range of practical applications, of which environmental sound analysis is one of the most important. In this paper, we explore the representation of audio data as graphs in the context of sound classification. We propose a methodology that leverages pre-trained audio models to extract deep features from audio files, which are then employed as node information to build graphs. Subsequently, we train various graph neural networks (GNNs), specifically graph convolutional networks (GCNs), GraphSAGE, and graph attention networks (GATs), to solve multi-class audio classification problems. Our findings underscore the effectiveness of employing graphs to represent audio data. Moreover, they highlight the competitive performance of GNNs in sound classification endeavors, with the GAT model emerging as the top performer, achieving a mean accuracy of 83% in classifying environmental sounds and 91% in identifying the land cover of a site based on its audio recording. In conclusion, this study provides novel insights into the potential of graph representation learning techniques for analyzing audio data.

3.
Article in Portuguese | LILACS-Express | LILACS, Index Psychology - journals | ID: biblio-1560154

ABSTRACT

O tempo foi amplamente investigado por Eugène Minkowski, retomando os conceitos de Henri Bergson de tempo cronológico e duração vivida. Apesar de algumas divergências, a influência bergsoniana contribuiu para os estudos de Minkowski, que buscou alcançar as características e as alterações do tempo vivido nos pacientes. A alteração na vivência do tempo — possivelmente intensificada na pandemia de Covid-19 — está no cerne da depressão de acordo com a psicopatologia fenomenológica. Assim, o objetivo deste artigo é ampliar a compreensão sobre o tempo vivido e a depressão durante esse período, o que é relevante considerando o acometimento de mais de 300 milhões de pessoas no mundo pela depressão e o aumento em 25% na sua prevalência global após o primeiro ano de contágio do vírus.


Resumos Time has been extensively investigated by Eugène Minkowski, taking up Henri Bergson's concepts of objective time and lived time. Despite some divergences, Bergsonian's influence contributed to the studies of Minkowski, who sought to reach the characteristics and alterations of lived time in patients. The alteration in the experience of time — possibly intensified during the COVID-19 pandemic — is placed at the core of depression according to phenomenological psychopathology. Thus, this study aims to expand the understanding of lived time and depression during the pandemic, which is relevant considering that more than 300 million people worldwide are affected by depression and that its global prevalence increased by 25% after the first year of the virus infection.


Le temps a fait l'objet de recherches par Eugène Minkowski, reprenant les concepts de temps chronologique et de durée vécue d'Henri Bergson. Malgré certaines divergences, l'influence bergsonienne a contribué aux études de Minkowski, qui cherchait à comprendre les caractéristiques et les changements du temps vécu chez les patients. Le changement dans l'experience du temps — peut-être intensifié pendant la pandémie de COVID-19 — est au cœur de la depression selon la psychopathologie phénoménologique. Cet article cherche donc à élargir la compréhension du temps vécu et de la dépression pendant cette période, ce qui est pertinent compte tenu du fait que plus de 300 millions de personnes dans le monde sont touchées par la dépression et l'augmentation de 25% de sa prévalence mondiale après la première année d'infection par le virus.


El tiempo fue ampliamente investigado por Eugène Minkowski, retomando los conceptos de Henri Bergson de tiempo cronológico y duración vivida. A pesar de algunas divergencias, la influencia bergsoniana contribuyó a los estudios de Minkowski, que pretendía llegar a las características y cambios del tiempo vivido en los pacientes. La alteración en la vivencia del tiempo — posiblemente intensificada en la pandemia del COVID-19 — está en el centro de la depresión según la psico-patología fenomenológica. El objetivo de este artículo es ampliar la comprensión del tiempo vivido y de la depresión durante este período, lo que es relevante considerando que la depresión afecta a más de 300 millones de personas en el mundo y que hubo un aumento del 25% en su prevalencia global después del primer ano de contagio del virus.

4.
Repert. med. cir ; 33(1): 88-92, 2024. ilus
Article in Spanish | LILACS, COLNAL | ID: biblio-1552679

ABSTRACT

Objetivo: determinar si la terapia neural es una opción de tratamiento que pueda ser utilizada sin la aparición de efectos adversos. Presentación del caso: se presenta y analiza el caso de una paciente que ingresó a urgencias por dolor abdominal generalizado diagnosticándose hematoma hepático y realizándosele una revisión de la literatura científica. Resultados: se procedió a efectuar laparotomía con cirugía de control de daños, obteniendo resultados satisfactorios con egreso hospitalario sin complicaciones agregadas. Conclusiones: la terapia neural es un tratamiento del cual no se tiene suficiente evidencia científica que avale su seguridad en los pacientes


Objective: to determine whether neural therapy is a treatment option which can be used without the occurrence of adverse effects. Case report: we present and analyze the case of a female patient who was admitted to the emergency room for generalized abdominal pain. A hepatic hematoma was diagnosed, and a review of the scientific literature was conducted. Results: a laparotomy with damage control surgery was performed, obtaining satisfactory outcomes, with hospital discharge without any added complications. Conclusions: neural therapy is a treatment for which there is not enough scientific evidence to support its safety in patients


Subject(s)
Humans
7.
Rev. cuba. oftalmol ; 36(3)sept. 2023.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1550936

ABSTRACT

Objetivo: Caracterizar los resultados refractivos del implante de una lente intraocular plegable de cámara posterior suturada al iris en la afaquia sin o con inadecuado soporte capsular. Métodos: Se realizó un estudio descriptivo, prospectivo y longitudinal, en el que se incluyeron 30 pacientes (30 ojos) seguidos por un período de un año de septiembre de 2019 a septiembre de 2021, después del implante de una lente intraocular de cámara posterior suturada al iris en la afaquia. Se les realizó examen oftalmológico completo y se evaluaron variables como mejor agudeza visual sin corrección, con corrección, resultados refractivos, presión intraocular, astigmatismo inducido, densidad celular y complicaciones. Resultados: La mejor agudeza visual sin corrección en el preoperatorio fue del 93,3 % (<0,1) y con corrección de 0,66, al año del posoperatorio fue de 0,493/0,890, respectivamente. La presión intraocular preoperatoria fue de 20,7 mmHg, y al año 19,7 mmHg. La densidad celular en el preoperatorio fue de 1755,7 cél/mm2 y al año fue de 1363,8 cél/mm2, y en los pacientes bien corregidos al mes del posoperatorio fue de 73,4 % y al año de 70 %. El astigmatismo inducido en el posoperatorio al año fue de -0,51 D. Conclusiones: La agudeza visual sin corrección y con corrección mejoran después del implante de una lente intraocular plegable de cámara posterior suturada al iris en la afaquia sin o con inadecuado soporte capsular. Predominan los pacientes bien corregidos, sin cambios en la presión intraocular y la complicación más frecuente fue el edema corneal.


Objective: To characterize the refractive outcomes of implanting a posterior chamber foldable intraocular lens sutured to the iris in aphakia without or with inadequate capsular support. Methods: A descriptive, prospective and longitudinal study was carried out, including 30 patients (30 eyes) followed up for a period of one year, from September 2019 to September 2021, after being implanted a posterior chamber intraocular lens sutured to the iris in aphakia. Complete ophthalmologic examination was performed and variables were assessed, such as best visual acuity without correction, with correction, refractive results, intraocular pressure, induced astigmatism, cell density and complications. Results: The best visual acuity without correction in the preoperative period was 93.3 % (<0.1) and 0.66 with correction; while one-year postoperative visual acuity was 0.493 and 0.890, respectively. Preoperative intraocular pressure was 20.7 mmHg, while it was 19.7 mmHg at one year. Preoperatively cell density was 1755.7 cells/mm2, and it was 1363.8 cells/mm2 at one year it; while in well-corrected patients, it was 73.4% at one month postoperatively and 70% at one year. Postoperative induced astigmatism at one year was -0.51 D. Conclusions: Both uncorrected and corrected visual acuity improve after implantation of a posterior chamber foldable intraocular lens sutured to the iris in aphakia without or with inadequate capsular support. Well-corrected patients predominate, with no change in intraocular pressure, while the most frequent complication was corneal edema.

8.
Sensors (Basel) ; 23(16)2023 Aug 10.
Article in English | MEDLINE | ID: mdl-37631608

ABSTRACT

Focal cortical dysplasia (FCD) is a congenital brain malformation that is closely associated with epilepsy. Early and accurate diagnosis is essential for effectively treating and managing FCD. Magnetic resonance imaging (MRI)-one of the most commonly used non-invasive neuroimaging methods for evaluating the structure of the brain-is often implemented along with automatic methods to diagnose FCD. In this review, we define three categories for FCD identification based on MRI: visual, semi-automatic, and fully automatic methods. By conducting a systematic review following the PRISMA statement, we identified 65 relevant papers that have contributed to our understanding of automatic FCD identification techniques. The results of this review present a comprehensive overview of the current state-of-the-art in the field of automatic FCD identification and highlight the progress made and challenges ahead in developing reliable, efficient methods for automatic FCD diagnosis using MRI images. Future developments in this area will most likely lead to the integration of these automatic identification tools into medical image-viewing software, providing neurologists and radiologists with enhanced diagnostic capabilities. Moreover, new MRI sequences and higher-field-strength scanners will offer improved resolution and anatomical detail for precise FCD characterization. This review summarizes the current state of automatic FCD identification, thereby contributing to a deeper understanding and the advancement of FCD diagnosis and management.


Subject(s)
Focal Cortical Dysplasia , Humans , Magnetic Resonance Imaging , Neuroimaging , Brain , Software
9.
Angiol. (Barcelona) ; 75(4): 268-272, Juli-Agos. 2023. ilus
Article in Spanish | IBECS | ID: ibc-223709

ABSTRACT

Introducción: el sangrado es una complicación común después de una amigdalectomía y habitualmente se tratacon cauterización del lecho quirúrgico. Sin embargo, en algunos pacientes, cuando el sangrado es secundario auna lesión vascular, es necesaria la ligadura o la embolización del vaso lesionado.Caso clínico: presentamos el caso de un paciente de 7 años de edad que requirió reparación y revascularizacióndel eje carotídeo izquierdo con injerto autólogo debido a sangrado recurrente y refractario a embolización de laarteria carótida externa izquierda posamigdalectomía.(AU)


Background: bleeding is a very common complication after tonsillectomy and is often treated through cauter-ization of the tonsillar bed. However, in some cases ligation or embolization of the source of the bleeding due tovascular injury is deemed necessary.Case report: this is the case of a 7-year-old boy that underwent repair and revascularization of his left carotid axiswith an autologous vascular graft due to recurrent bleeding postonsillectomy refractory to previous embolizationof the left external carotid artery.(AU)


Subject(s)
Humans , Male , Child , Vascular Grafting , Vascular System Injuries , Vascular Surgical Procedures , Tonsillectomy , Carotid Arteries/surgery , Carotid Artery, Internal/surgery , Inpatients , Physical Examination , Pediatrics , Hemorrhage , Adenoidectomy
10.
Materials (Basel) ; 16(3)2023 Jan 17.
Article in English | MEDLINE | ID: mdl-36769911

ABSTRACT

Carbon fibers are materials with potential applications for CO2 capture due to their porous structure and high surface areas. Nevertheless, controlling their porosity at a microscale remains challenging. The solution plasma (SP) process provides a fast synthesis route for carbon materials when organic precursors are used. During the discharge and formation of carbon materials in solution, a soot product-denominated solution plasma-generated seeds (SPGS) is simultaneously produced at room temperature and atmospheric pressure. Here, we propose a preparation method for carbon fibers with different and distinctive morphologies. The control over the morphology is also demonstrated by the use of different formulations.

11.
Australas Psychiatry ; 31(2): 209-212, 2023 04.
Article in English | MEDLINE | ID: mdl-36657114

ABSTRACT

OBJECTIVE: The primary objective of this study was to use clinical indicators to track changes in efficiency of a Consultation-Liaison service as part of a clinical audit cycle. METHODS: This was a clinical audit cycle. The auditing phase involved measuring the efficiency of the service. The 'intervention' was simply the team's awareness and involvement in tracking these statistics. Subsequently, these indicators were re-audited. RESULTS: In the initial audit cycle, 315 referrals to the C-L service were audited over a 3 month period, showing a 24 hour time-to-seen rate of 80% and a 36 hour time-to-seen rate of 89.2%. Upon re-auditing of 112 referrals following our intervention, 24 hr timeliness had risen to 92% and 36 hr timeliness had risen to 96.4%. CONCLUSION: The measuring of clinical indicators of efficiency in C-L may give service improvement personnel a reflection of the functionality of a C-L service. By involving team members in the measuring and tracking of these indicators, we may be able to boost overall clinical efficiency and outcomes.


Subject(s)
Clinical Audit , Mental Health Services , Humans , Referral and Consultation , Time Factors , Hospitals, Urban
12.
Child Abuse Negl ; 142(Pt 2): 105849, 2023 Aug.
Article in English | MEDLINE | ID: mdl-36369043

ABSTRACT

BACKGROUND: Boys subject to intrafamilial child sexual exploitation and abuse (CSEA) - in particular, cases which begin as incest and later evolve into child trafficking for sexual exploitation - face many barriers in disclosing their exploitation, often leaving victims and survivors feeling isolated from society and dismissed or mishandled by service providers such as law enforcement officers, child protection specialists, medical staff and mental health professionals. OBJECTIVE: This study explores the unique characteristics of intrafamilial CSEA through the sex trafficking of boys, and the barriers to disclosure and recovery experienced by male victims and survivors. PARTICIPANTS AND SETTING: Ten adult male survivors of intrafamilial child trafficking for sexual exploitation were interviewed multiple times to gain a deeper understanding of intrafamilial CSEA and how it compares and contrasts with non-familial CSEA. Participants in this study primarily came from North America. METHODOLOGY: Multiple semi-structured online interviews were conducted with these 10 adult male survivors because they experienced 1) intrafamilial CSEA and 2) being trafficked by their families to be sexually exploited by non-familial perpetrators. The participants were then asked to compare and contrast intrafamilial and non-familial CSEA. The research team employed a descriptive phenomenological approach and interview transcripts were coded, analyzed, and compared to identify patterns of non-verbal CSEA indicators and thematic narratives. The study also explored the internal and external barriers to disclosure reported by participants. Trauma-informed, person-centered practices were used throughout the entirety of the study to minimize harm to participants. The research team employed a co-productive approach using participants' initial interviews and feedback to formulate new questions for later rounds of interviews and by having the participants confirm the accuracy of their respective quotes and case summaries. RESULTS AND DISCUSSION: This study highlights several CSEA modalities, such as "boy-swap" events and local/national/transnational trafficking rings engaged in CSEA of boys. It also discusses how survivors' experiences differed between intrafamilial and non-familial CSEA and trafficking, and how familial settings may facilitate concealment of CSEA. Participants described various modus operandi used by abusers, traffickers, and buyers of all genders. While all 10 intrafamilial CSEA cases included male perpetrators, female perpetrators were also present in nine of them. In addition, participants identified various psychological and physiological CSEA and trafficking indicators that evidenced their victimization during their childhood years. All 10 survivors reported long-term health consequences into adulthood and scored highly on Adverse Childhood Experiences (ACEs) questionnaires. RECOMMENDATIONS AND CONCLUSION: Findings underscore the importance of trauma-informed practices for identifying, liberating, and rehabilitating victims and survivors. Participants reported receiving more effective assistance from service providers that exhibited trauma-informed practices. Traditional gender stereotypes may hinder the ability of service providers to recognize and provide support to boys victimized and trafficked by their families for CSEA. Consequently, service providers may stand to benefit from training on 1) trauma-informed, person-centered practices and 2) conscious and unconscious biases, particularly those related to gender. Survivors in recovery require expanded support services, such as the provision of safe housing, online/in-person support communities, and professional/life skill training. Co-productive research methods that integrate the views and experiences of CSEA and trafficking survivors are also recommended.


Subject(s)
Child Abuse, Sexual , Child Abuse , Crime Victims , Human Trafficking , Adult , Child , Humans , Female , Male , Child Abuse, Sexual/psychology , Child Abuse/psychology , Sexual Behavior , Survivors/psychology , Human Trafficking/psychology
13.
Article in English | LILACS, Index Psychology - journals | ID: biblio-1529077

ABSTRACT

Abstract University students are particularly susceptible to suicidal ideation and behavior due to issues inherent to this vital lives' moment. The Rorschach test can help to understand these students' suffering. The objective was to evaluate perception, thinking, stress, and distress in the Rorschach test domains in university students attended at a public university mental health service, comparing students with suicidal ideation with those without it. A total of 36 students aged 18 or over were assessed. The instruments were: Rorschach Performance Assessment System (R-PAS), Columbia Suicide Severity Rating Scale (C-SSRS) and Self Report Questionnaire (SRQ-20). Two analyses were performed using Wilcoxon Mann-Whitney test, according to the presence of suicidal ideation in the last 30 days (SRQ-20) and in the last six months (C-SSRS). Statistically significant differences were found in the two analyses, indicative of greater perceptual distortion in students without suicidal ideation and of stress and distress in students with ideation.


Resumo Estudantes universitários são particularmente suscetíveis a ideação e comportamento suicidas decorrentes de problemas inerentes a este momento vital. O método de Rorschach pode contribuir na compreensão do sofrimento destes estudantes. O objetivo do estudo foi avaliar os domínios percepção, pensamento, estresse e angústia no Rorschach de estudantes universitários atendidos em serviço de saúde mental de universidade pública, comparando estudantes com ideação suicida com aqueles sem ideação. Foram avaliados 36 estudantes com 18 anos ou mais. Os instrumentos foram: Rorschach Performance Assessment System (R-PAS), Escala de Avaliação do Risco de Suicídio de Columbia (C-SSRS) e Self Report Questionnaire (SRQ-20). Foram realizadas duas análises com teste de Wilcoxon Mann-Whitney, segundo a presença de ideação nos últimos 30 dias (SRQ-20) e nos últimos 6 meses (C-SSRS). Foram observadas diferenças estatísticas significativas nas duas análises, indicativas de maior distorção perceptiva nos alunos sem ideação suicida e de angústia e estresse nos estudantes com ideação.


Resumen Estudiantes universitarios son particularmente susceptibles a ideación y comportamiento suicida debido a problemas inherentes a este momento vital. El Rorschach puede ayudar a comprender su sufrimiento. El objetivo fue evaluar los dominios percepción, pensamiento, estrés y angustia en el Rorschach de universitarios atendidos en un servicio de salud mental de universidad pública, comparando estudiantes con ideación suicida con aquellos sin esa ideación. Se evaluaron 36 estudiantes de pregrado y posgrado de 18 años o más. Los instrumentos fueron: Rorschach Performance Assessment System, Escala Columbia para Evaluar la Seriedad de la Ideación Suicida (C-SSRS) y Self Report Questionnaire (SRQ-20). Se realizaron dos análisis con Wilcoxon Mann-Whitney test, según la presencia de ideación en los últimos 30 días (SRQ-20) y en los últimos 6 meses (C-SSRS). Hubo diferencias estadísticamente significativas en los dos análisis, indicativas de mayor distorsión perceptiva en estudiantes sin ideación suicida y de angustia y estrés en estudiantes con ideación.


Subject(s)
Humans , Adult , Rorschach Test , Stress, Psychological , Students , Suicide , Universities
14.
Psicol. Estud. (Online) ; 28: e52050, 2023.
Article in Portuguese | LILACS, Index Psychology - journals | ID: biblio-1431111

ABSTRACT

RESUMO. Os serviços mediados pela internet oferecem uma diversidade de formas de conexão e interatividade e, em decorrência, surgem novas intervenções em saúde mental, exigindo pesquisas que fundamentem e avaliem tais práticas. Entretanto, os estudos na área são escassos, especialmente diretrizes que auxiliem na condução de pesquisas que envolvam as intervenções baseadas na internet. Nesse sentido, o objetivo deste artigo é indicar orientações para o desenho de pesquisas de intervenção psicológica na internet, tendo como ilustração a construção de uma pesquisa interventiva em psicoterapia on-line, qualitativa, descritiva e longitudinal. São abordados seis aspectos significativos para pesquisas em intervenção digital, incluindo contato com colaboradores, critérios de participação, alcances da pesquisa, monitoramento e avaliação das intervenções, critérios tecnológicos e aspectos éticos no campo digital. São levantados aspectos técnicos, qualitativos e de cuidados necessários para manter a qualidade dos atendimentos e das pesquisas mediadas pelas tecnologias digitais. É urgente à psicologia consolidar um campo de saber que se ocupe tanto das influências das tecnologias nas subjetividades, também, delinear estudos que avaliem com rigor científico o uso da internet para o tratamento e cuidado em saúde mental.


RESUMEN. Los servicios mediados por Internet ofrecen una diversidad de formas de conexión e interactividad y, como resultado, surgen nuevas intervenciones en salud mental, que requieren investigaciones que corroboren y evalúen dichas prácticas. Sin embargo, los estudios en el área son escasos, especialmente las directrices que ayudan a realizar investigaciones que involucran intervenciones basadas en Internet. En este sentido, el objetivo de este artículo es indicar directrices para el diseño de investigación de intervención psicológica en Internet, teniendo como ilustración la construcción de una investigación intervencionista en psicoterapia online, cualitativa, descriptiva y longitudinal. Se abordan seis aspectos significativos para la investigación en intervención digital, incluyendo el contacto con colaboradores, los criterios de participación, el alcance de la investigación, el seguimiento y evaluación de las intervenciones, los criterios tecnológicos y los aspectos éticos en el campo digital. Se plantean aspectos técnicos, cualitativos y asistenciales necesarios para mantener la calidad asistencial y la investigación mediada por las tecnologías digitales. Es urgente que la Psicología consolide un campo de conocimiento que se ocupe tanto de las influencias de las tecnologías en las subjetividades como de esbozar estudios que evalúen con rigor científico el uso de Internet para el tratamiento y cuidado en salud mental.


ABSTRACT Internet-mediated services offer a variety form of connection and interactivity, from this, new mental health interventions emerge, requiring research to validate and evaluate such practices. However, studies in the area are scarce, especially guidelines that assist in conducting research involving Internet-based interventions. The purpose of this study was to indicate guidelines for the design of psychological intervention research mediated by the Internet, based on the construction of an interventional research in online, qualitative, descriptive and longitudinal psychotherapy. Six significant aspects for digital intervention. Six significant aspects for research in digital intervention are addressed, including contact with collaborators, criteria for participation, scope of research, monitoring and evaluation of interventions, technological criteria and ethical aspects in the digital field. Technical, qualitative and care aspects necessary to maintain the quality of care and research mediated by digital technologies are raised. It is urgent for Psychology to consolidate a field of knowledge that deals with the influence of technologies on subjectivities, as well as to design studies that scientifically assess the use of the internet for treatment and care in mental health.


Subject(s)
Internet-Based Intervention/trends , Psychosocial Intervention/trends , Psychology, Clinical/instrumentation , Psychotherapy/instrumentation , Medical Informatics/instrumentation , Review Literature as Topic , Mental Health/trends , Mental Health Teletherapy , Digital Technology/trends
15.
Acta méd. colomb ; 47(4)dic. 2022.
Article in English | LILACS-Express | LILACS | ID: biblio-1533455

ABSTRACT

Lecithin-cholesterol acyltransferase deficiency is a rare genetic disease caused by a mutation of the gene coding for the lecithin-cholesterol acyltransferase protein, and mainly affects low density lipoprotein metabolism. It typically manifests with diffuse corneal opacities, normocytic anemia and kidney disease. We present the case of a 30-year-old man with chronic kidney disease and nephrotic syndrome. His initial kidney biopsy showed focal segmental glomerulosclerosis, thought to be primary, a disease which was refractory to multiple immunosuppressive schemes. Manifestations such as anemia, splenomegaly, corneal opacities and an association with low high-density lipoproteins alerted to the possibility of glomerular damage secondary to lecithin-cholesterol acyltransferase enzyme deficiency, which was confirmed through genetic sequenc ing. Due to the low incidence of the disease, diagnosis is a clinical challenge. The signs and symptoms tend to be interpreted as isolated events, which significantly delays its confirmation. Understanding this entity and the clinical exercise needed to arrive at its diagnosis will serve as a reference, resulting in the suspicion and reporting of cases in the future. (Acta Med Colomb 2022; 47. DOI:https://doi.org/10.36104/amc.2022.2558).


La deficiencia de lecitin-colesterol aciltransferasa es una enfermedad genética rara, causada por una mutación en el gen que codifica la proteína lecitin-colesterol aciltransferasa y afecta principalmente el metabolismo de las lipoproteínas de baja densidad. Se manifiesta típicamente con opacidades corneales difusas, anemia normocítica y enfermedad renal. Se presenta el caso de un hombre de 30 años con enfermedad renal crónica y síndrome nefrótico, con biopsia renal inicial que demostró un patrón de glomeruloesclerosis focal y segmentaria, interpretada como primaria, enfermedad que fue refractaria a múltiples esquemas de inmunosupresión. Las manifestaciones como anemia, esplenomegalia, opacidades corneales y la asociación con lipoproteínas de alta densidad bajas, alertaron sobre la posibilidad de compromiso glomerular secundario a un déficit de la enzima lecitin-colesterol aciltransferasa, confirmado mediante estudio de secuenciación genética. Dada la baja incidencia de la enfermedad, el diagnóstico representa un desafío clínico. Las manifestaciones suelen interpretarse como eventos aislados, lo que lleva a retraso significativo en su confirmación. El conocimiento de esta entidad y el ejercicio clínico necesario para llegar al diagnóstico, servirán como referencia que derive en la sospecha y reporte de futuros casos. (Acta Med Colomb 2022; 47. DOI:https://doi.org/10.36104/amc.2022.2558).

16.
Vínculo ; 19(1): 37-47, 20220000.
Article in Portuguese | LILACS, Index Psychology - journals | ID: biblio-1434325

ABSTRACT

O modelo do psicodiagnóstico interventivo em grupo de pais no contexto da Clínica-escola considera a variabilidade de demandas clínicas, os objetivos formativos, a oferta de atendimento psicológico e a vulnerabilidade social da clientela assistida. Este método extrapola objetivos investigativos distinguindo-se pela realização de intervenções durante os procedimentos de avaliação psicológica. Uma série de devolutivas parciais são realizadas para intensificação dos efeitos terapêuticos, discutindo-se os resultados das técnicas diagnósticas no grupo de pais. O objetivo deste trabalho é apresentar o potencial clínico de um dispositivo do diagnóstico interventivo que considera os instrumentos de avaliação como objetos mediadores e trabalha-os grupalmente. Trata-se de um estudo teórico-clínico que discute o potencial do dispositivo através de duas vinhetas clínicas que permitirem a discussão das possibilidades terapêuticas das sessões devolutivas realizadas em grupo de pais na situação do psicodiagnóstico interventivo. Focaliza-se a última devolutiva conduzida pela atividade de recorte e colagem, tomada como expressão do alcance terapêutico do procedimento clínico em questão. Apresenta-se a hipótese de que as técnicas diagnósticas podem ser pensadas como objetos mediadores e guias para o trabalho com os pais.


The interventional parent'group psychodiagnostic model in the context of the School-Clinic considers the variability of the clinical demands, the educational goal, psychological care's and the social vulnerability of those assisted. This method goes beyond the investigative objectives, distinguishing itself by carrying out interventions during the process of the psychological assessment. Thus, a series of partial feedbacks are carried out so to intensify the therapeutic effects. The objective of this study is to present the clinical potential of an interventional diagnostic device that considers assessment instruments as mediating objects and works on them in groups. This is a theoretical-clinical study that discusses the potential of the device through two clinical vignettes that allow the discussion of the therapeutic possibilities of the feedback sessions held in a group of parents. It focuses on the last partial feedback session conducted from the cut-and-past activity which is seen as an expression of the therapeutic reach of the clinical procedure here discussed. It presents the hypothesis that diagnostic techniques can be thought of as mediating objects and guide for working with the parents.


El modelo de psicodiagnóstico intervencionista en un grupo de padres en el contexto de la Escuela-Clínica considera la variabilidad de las demandas clínicas, los objetivos formativos, la oferta de atención psicológica y la vulnerabilidad social de la clientela asistida. Este método va más allá de los objetivos investigativos, diferenciándose por realizar intervenciones durante los procedimientos de evaluación psicológica. Se realizan una serie de devolución parciales para intensificar los efectos terapêuticos. El objetivo de este trabajo es presentar el potencial clínico de un dispositivo de diagnóstico intervencionista que considera los instrumentos de evaluación como objetos mediadores y los trabaja en grupo. Se trata de un estudio teórico-clínico que analiza el potencial del dispositivo a través de dos viñetas clínicas que permiten discutir las posibilidades terapéuticas de las sesiones de devolución. Se centra en la entrevista final realizada por la actividad de cortar y pegar y que se toma como expresión del alcance terapéutico del procedimiento clínico en cuestión. Se plantea la hipótesis de que las técnicas de diagnóstico pueden concebirse como objetos mediadores y guías para trabajar con los padres.


Subject(s)
Humans , Parents , Patient Advocacy , Diagnosis , Psychiatric Rehabilitation , Interview, Psychological
17.
J Agric Food Chem ; 70(39): 12596-12603, 2022 Oct 05.
Article in English | MEDLINE | ID: mdl-36154047

ABSTRACT

Despite the recent approval of stingless bee honey to the Argentine Food Code, there are still many gaps in information. Likely, the main reason for this is that multiple ecological and chemical factors influence their production and antimicrobial properties. This work combined metabolomic, microbiological, and physicochemical analyses to characterize the honey ofTetragonisca fiebrigifrom Northeastern Argentina. The antimicrobial activity tests showed that honey samples (n = 24) inhibited some Gram-positive and Gram-negative bacteria at different sensitivity levels. Furthermore, samples selected for their high bioactivity revealed crystallizations, a positive correlation with fungal growth, and the presence of flavonoids. The major polyphenols annotated by liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis and supported by metabolomic tools were quercetin 3,4'-dimethyl ether, pachypodol, jaceoside, irigenin trimethyl ether, corymboside, chrysoeriol 7-neohesperidoside, and corymboside. In contrast, samples missing antimicrobial activity did not crystallize, lacked flavonoids, and were enriched in phenylethylamides. Based on these findings, we discuss the significance of flavonoids and phenylethylamides on honey's antimicrobial activity and food quality and how they may indeed reflect essential parameters of the hive, such as microbial balance and eubiosis.


Subject(s)
Anti-Infective Agents , Honey , Animals , Anti-Bacterial Agents/analysis , Anti-Bacterial Agents/pharmacology , Anti-Infective Agents/pharmacology , Bees , Chromatography, Liquid , Ethers , Flavonoids/analysis , Flavonoids/pharmacology , Gram-Negative Bacteria , Gram-Positive Bacteria , Honey/analysis , Quercetin/analysis , Tandem Mass Spectrometry
18.
Einstein (Sao Paulo) ; 20: eAO8013, 2022.
Article in English | MEDLINE | ID: mdl-35766673

ABSTRACT

OBJECTIVE: To determine the rate of complications associated with the use of temporary pacemakers in patients in the waiting list for the definitive pacemaker implantation in a public hospital located in São Paulo, SP, Brazil. METHODS: Retrospective observational study based on data extracted from medical records of patients admitted to Hospital Municipal Dr. Moyses Deutsch, Hospital Israelita Albert Einstein from January 2014 to December 2018. Patients aged 18 years or older, diagnosed with high degree atrioventricular block upon admission and with indications for definitive pacemaker implantation were included. All-cause mortality, clinical and surgical complications and length of hospital stay while waiting for the procedure were defined as primary outcomes. RESULTS: The sample comprised 66 patient allocated to one of two groups: with and without the need of temporary pacemaker while in hospital (n=45 and n=21, respectively). The rate of complications was higher in patients who used a temporary pacemaker (p<0.001). These included primarily pneumonia (p=0.048) and length of hospital stay (p=0.029). CONCLUSION: Patients who required a temporary pacemaker stayed longer in hospital. Longer hospital stay is associated with higher rates of general complications and all-cause mortality.


Subject(s)
Atrioventricular Block , Pacemaker, Artificial , Atrioventricular Block/diagnosis , Atrioventricular Block/therapy , Brazil , Humans , Length of Stay , Pacemaker, Artificial/adverse effects , Retrospective Studies , Treatment Outcome
19.
Rev. argent. cardiol ; 90(6): 437-443, 2022. tab
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1529548

ABSTRACT

RESUMEN Introducción: Si bien el principal objetivo del ecocardiograma estrés (EE) es analizar los cambios en la motilidad parietal, el análisis de otras variables como la reserva contráctil (RCon) por el método de elastancia y la reserva cronotrópica (RCro) permiten agregar valor pronóstico al estudio. No obstante, las mismas no suelen analizarse ni informarse en la mayoría de los estudios de EE en nuestro medio. Objetivos: Comparar las características clínicas y ecocardiográficas de pacientes a quienes se les realizó un EE con ejercicio negativo para isquemia miocárdica de acuerdo con la presencia o no de RCon y RCro. Material y métodos: Estudio retrospectivo realizado sobre 73 pacientes con EE con ejercicio, sin isquemia. De acuerdo con la presencia o ausencia de RCon y RCro se los dividió en tres grupos. Grupo 1: presencia de ambas reservas; grupo 2: presencia de solo una reserva y grupo 3: ausencia de ambas reservas. La RCon se determinó mediante el cociente entre la tensión arterial sistólica y el volumen de fin de sístole tanto en reposo como en estrés (Valor normal: > 2) y la RCro se definió como el aumento mayor al 80% de la frecuencia cardíaca basal. Resultados: Se incluyeron 73 pacientes (64% varones, edad 63 ± 12 años). En el Grupo 1 se incluyeron 23 pacientes (62% varones, 59,8 ± 12,5 años), en el grupo 2, 29 pacientes (65% varones, 60,7 ± 13 años) y en el grupo 3, 21 pacientes (65% varones, 68,8 ± 7,8 años). Los pacientes sin ninguna reserva fueron más añosos y presentaron una tendencia a mayor prevalencia de los factores de riesgo tradicionales, más antecedentes de IAM y mayor uso de betabloqueantes. Desde el punto de vista ecocardiográfico, este mismo grupo presentó menores valores de fracción de eyección ventricular izquierda (FEVI) y strain longitudinal global (SLG) tanto en reposo como en esfuerzo, mayor masa ventricular, y en la ergometría menor cantidad de minutos de ejercicio realizado. Se realizó una regresión logística binaria con aquellas variables asociadas a la ausencia de RCon y RCro. La edad (OR 1,12, IC95% 1,02-1,22; p = 0,01) y el valor de SLG en reposo (OR 0,68, IC95% 0,51-0,90; p= 0,008) fueron las variables asociadas en forma independiente a la ausencia de ambas reservas. En una curva ROC, un valor de SLG de -18% fue el mejor punto de corte (área bajo la curva 0,72; IC 95% 0,57-0,87). Conclusiones: Los pacientes con EE negativo para isquemia miocárdica, y que además presentan ausencia de RCon y RCro tienen un perfil de riesgo más elevado. Esto podría estar asociado a mayor riesgo de eventos cardiovasculares durante el seguimiento.


ABSTRACT Background: While the primary objective of the stress echocardiography (stress echo) is to assess wall motion abnormalities, evaluation of other variables, such as contractile reserve (CR) via elastance, and chronotropic reserve (ChR), may add prognostic value to the study. However, these are unusually evaluated or reported in most stress echo studies in our field. Objectives: To compare clinical and echocardiographic characteristics in patients undergoing an exercise stress echo with negative results for myocardial ischemia based on the presence or absence of CR and ChR. Methods: A rRetrospective study in 73 patients, with exercise stress echo and no ischemia. Patients were divided into three groups, based on the presence or absence of CR and ChR. Group 1: presence of both; Group 2: presence of either of the two, and Group 3: absence of both. The CR was established using as the systolic blood pressure and end-systolic volume ratio, both at rest and under stress (normal value: >2), and the ChR was defined as a more than 80% increase in baseline heart rate. Results: The study enrolled 73 patients (64% males, aged 63±12 years). Group 1 included 23 patients (62% males, agedaged 59.8±12.5 years); Group 2 included 29 patients (65% males, aged 60.7±13 years), and Group 3 included 21 patients (65% males, aged 68.8±7.8 years). Patients with no reserve were older and showed a tendency to higher prevalence of traditional risk factors, a longer history of AMI and increased use of beta blockers. In the Echocardiographicallyechocardiographic study, his group had lower values of left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) both at rest and under stress, a larger ventricular mass, and less minutes of exercise according toin the exercise stress test. A binary logistic regression was performed using variables associated with the absence of CR and ChR. Age (OR 1.12, 95% CI 1.02-1.22; p=0.01) and GLS at rest (OR 0.68, 95% CI 0.51-0.90; p=0.008) were variables independently associated with the absence of both reserves. On a ROC curve, a GLS of -18% was the best cutoff point (area under the curve 0.72). Conclusion: Patients with a stress echo negative for myocardial ischemia and absence of CR and ChR have a higher risk profile. This could be associated with a higher risk of cardiovascular events during the follow-up.

20.
Article in English | LILACS, Index Psychology - journals | ID: biblio-1375423

ABSTRACT

Most countries did not have a consolidated digital health structure before the pandemic. Both social distancing and mental health problems resulting from the situation justify the urgency of discussions on web-mediated interventions. The objective of this work is to present the panorama of technological mediation in mental health services and their specificities in the context of the pandemic. This paper is grounded on a critical look at the migration from face-to-face care to the Internet environment, highlighting: the international experiences using digital technologies in the pandemic context; the challenges in online consultations, emphasizing the importance of the ethical, technical/technological, and clinical domains, which are recurring issues in the international literature; the challenges and perspectives in the use of technologies. It is essential to develop strategies aligned with government incentives, aiming at the quality of the offered services and the guarantee of an adequate hybrid qualification.


A maioria dos países não possuía uma estrutura de saúde digital consolidada antes da pandemia. Tanto o distanciamento social quanto os agravos psicológicos decorrentes da própria situação justificam a urgência de discussões científicas sobre intervenções mediadas pela web. O objetivo deste trabalho é apresentar o panorama da mediação tecnológica nos serviços de saúde mental e suas especificidades no contexto da pandemia. Parte-se de um olhar crítico diante da migração do cuidado face a face ao ambiente da Internet, ressaltando: experiências internacionais no uso das tecnologias digitais no contexto da pandemia; desafios nas consultas online, com destaque à importância dos domínios ético, técnico/tecnológico e da clínica recorrentes na literatura internacional; desafios e perspectivas do uso das tecnologias. É imprescindível desenvolver estratégias com incentivo governamental, visando a qualidade dos serviços oferecidos e a garantia de formação híbrida adequada.


Subject(s)
Mental Health , Telemedicine , Mental Health Teletherapy , COVID-19
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