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2.
Zentralbl Chir ; 132(6): 547-53, 2007 Dec.
Article in German | MEDLINE | ID: mdl-18098084

ABSTRACT

Patients with bony defects of the proximal femur after trochanteric fracture, implant failure (cut-out), periprosthetic fracture or aseptic loosening of prosthesis are difficult to treat with primary or revision endoprosthesis. Modular femoral hip prosthesis (MHP) with stems of different length and the possibility of distal interlocking screws are an operative solution for those patients. In a prospective study from January 1996 to January 2002 all patients treated with a MHP because of proximal and / or distal femoral bony defect or fracture were included. Follow-up after 6 to 30 months was evaluated clinically and radiologically in hospital. Change of modified Harris Hip Score and radiological signs of loosening (radiolucent line, migration of MHP, breaking interlocking screw) were documented. 106 patients with a follow-up of 58.5 % were included in the study. At time of follow-up clinical and radiological outcome after trochanteric fracture was good. Harris Hip Score was comparable to the situation of patients before fracture, only one MHP was loose. However in patients after revision arthroplasty 25 % of MHP were loose and in many patients the interlocking screw was broken. Distal interlocking screw in MHP prevents stability after trochanteric fracture to achieve osseointegration. However in case of periprosthetic fracture or revision arthroplasty MHP shows insufficient stability in many cases.


Subject(s)
Arthroplasty, Replacement, Hip , Bone Screws , Hip Fractures/surgery , Hip Prosthesis , Postoperative Complications/surgery , Prosthesis Failure , Aged , Aged, 80 and over , Female , Follow-Up Studies , Fracture Healing , Hip Fractures/diagnostic imaging , Humans , Male , Middle Aged , Osseointegration/physiology , Osteoarthritis, Hip/diagnostic imaging , Osteoarthritis, Hip/surgery , Postoperative Complications/diagnostic imaging , Prospective Studies , Prosthesis Design , Prosthesis Fitting , Radiography , Reoperation
3.
Unfallchirurg ; 110(11): 946-52, 2007 Nov.
Article in German | MEDLINE | ID: mdl-17989949

ABSTRACT

OBJECTIVE: Spinal trauma is frequently found in multiply injured patients. To gain more insight into the epidemiology and the clinical course of this entity, we analyzed the relevant data held in the German Trauma Registry (German Trauma Society, DGU). The Registry provides prospective, standardized and anonymous documentation on severely injured patients at different predetermined time points from the site of the accident until they are discharged from hospital. METHODS: Out of 8,057 patients whose details are recorded in the German Trauma Registry, 772 (approximately 10%) with severe spine trauma (AIS>/=3) patients were identified. Far more men (72%) than women (28%) had such spinal injuries. The mean age of the patients with severe spine injury was 37+/-17 years; their mean Injury Severity Score (ISS) was 29+/-15 (range 9-75) points. RESULTS: The age group 15-54 years was the largest (80%). Motor vehicle accidents (MVA) were the most frequent cause of severe spine trauma (49%), followed by falls from a great height (20%). About half of all severe spine injuries were not suspected in the prehospital setting. Symptoms of incomplete paraplegia were found in 20% of the patients and symptoms of complete paraplegia, in 27%. Patients with injuries to the thoracic spine more often had a lengthy average stay in the intensive care unit, because they were accompanied by thoracic trauma significantly more often than were injuries to the other spinal segments (96% vs 37%). Patients who underwent spinal surgery at an early stage (70% operated on <72 h after their injuries were sustained) showed a tendency to shorter periods ventilatory support and did not remain in the intensive care unit or indeed in the hospital as long as the other patients. Seventy-eight percent of the patients had survived for 90 days after sustaining their injuries. CONCLUSION: Almost 10% of all documented cases of patients with severe injuries in the German Trauma Registry had severe spinal injuries. These injuries were frequently not recognized or their extent underestimated in the preclinical setting. About 70% underwent spine stabilization within 72 h after being injured. These results support previous findings suggesting that early stabilization of vertebral fractures might be beneficial in multiply injured patients.


Subject(s)
Multiple Trauma/epidemiology , Registries , Spinal Fractures/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Cross-Sectional Studies , Female , Germany , Humans , Incidence , Infant , Injury Severity Score , Male , Middle Aged , Multiple Trauma/mortality , Spinal Fractures/mortality , Survival Analysis
4.
Unfallchirurg ; 109(9): 743-53, 2006 Sep.
Article in German | MEDLINE | ID: mdl-16897028

ABSTRACT

Spondylodiscitis is a rare bacterial infection of the spine with an inflammatory, destructive course. To obtain further information on the therapeutic management and clinical course of spondylodiscitis, we retrospectively investigated 78 patients after surgical intervention. Mean age was 64 years (+/-4.6 years; range 21-80 years), the mean length of stay 49 days (+/-8.2 days; 3-121 days) including 24 days (+/-4.7 days; 0-112 days) in ICU. In hospital mortality was 9%. The cervical spine was affected in 10%, the thoracic spine in 35% and the lumbar/sacral spine in 55% of patients. Abscess formation occurred in 65% and destruction of the vertebral body in 74%. A total of 75% of patients presented with neurological deficits which could be improved by surgical intervention in 82% of cases. 24 patients were treated by ventral debridement and stabilization alone, 20 patients with a combined dorsoventral method. Most patients (n=34) were stabilized via dorsal bridging instrumentation without ventral debridement of the focus. Of this group, 23 patients were initially scheduled for secondary ventral debridement but complete healing was achieved prior to this, so further surgical therapy was unnecessary. Successful cure was obtained in 92% of cases. Based on our findings, we favor a split surgical approach: initially with dorsal internal fixation only. Abscesses can be drained percutaneously. Ventral debridement and stabilization is only recommended if insufficient stability can be obtained by dorsal fixation alone, as shown by the persistence of infection or pain.


Subject(s)
Cervical Vertebrae , Discitis/surgery , Lumbar Vertebrae , Sacrum , Thoracic Vertebrae , Adult , Aged , Aged, 80 and over , Debridement , Discitis/diagnosis , Drainage , Female , Humans , Length of Stay , Magnetic Resonance Imaging , Male , Middle Aged , Postoperative Complications , Retrospective Studies , Spinal Fusion , Treatment Outcome
5.
MMW Fortschr Med ; 147(45): 67-8, 2005 Nov 10.
Article in German | MEDLINE | ID: mdl-16320659

ABSTRACT

The distal radius is the most common site of a fracture. The type of fracture presenting, stability/instability and concomitant injuries are the factors that determine whether the fracture should be treated conservatively or surgically. Possible sequelae include a dystrophy syndrome.


Subject(s)
Radius Fractures/therapy , Aged , Aged, 80 and over , External Fixators , Female , Fracture Fixation/instrumentation , Humans , Immobilization , Joint Instability/diagnosis , Joint Instability/etiology , Radius Fractures/complications , Radius Fractures/diagnosis , Radius Fractures/diagnostic imaging , Radius Fractures/surgery , Time Factors , Tomography, X-Ray Computed , Wrist Joint
6.
Zentralbl Chir ; 130(2): 142-7, 2005 Apr.
Article in German | MEDLINE | ID: mdl-15849659

ABSTRACT

Hospital mortality after hip fracture in elderly patients has decreased significantly in previous years. However, patients often show reduction of daily life activity. The aim of the following study was to assess clinical and radiological results nine months after operation of hip fracture. A total of 127 patients (mean age 77.2 years) were stabilized by arthroplasty because of femoral neck fractures or by gamma locking nail because of trochanteric fractures. Modified Harris-Hip-Score as well as social situation at time of follow-up compared to pretrauma situation were evaluated. Hospital mortality was 3.2 percent. Follow-up could be performed in 78 patients clinically and radiologically by examination in the hospital. At time of follow-up 19.7 percent of patients had already died independent of the operative procedure. Only 65 percent of patients were able to live at home. Modified Harris-Hip-Score at follow-up was decreased significantly by 16 points compared to the situation before the trauma. The reduction of the score was caused mainly by deterioration of hip function and less by femoral or hip pain. In future the main scope after hip fracture must be an improvement of rehabilitation of elderly patients.


Subject(s)
Activities of Daily Living , Femoral Neck Fractures/rehabilitation , Hip Fractures/rehabilitation , Accidental Falls , Age Factors , Aged , Aged, 80 and over , Arthroplasty, Replacement, Hip , Bone Nails , Data Interpretation, Statistical , Exercise Therapy , Female , Femoral Neck Fractures/etiology , Femoral Neck Fractures/surgery , Follow-Up Studies , Fracture Fixation, Internal/instrumentation , Hip Fractures/etiology , Hip Fractures/surgery , Hospital Mortality , Humans , Male , Postoperative Complications , Prospective Studies , Sex Factors , Time Factors , Walking
7.
Clin Orthop Relat Res ; (418): 225-30, 2004 Jan.
Article in English | MEDLINE | ID: mdl-15043122

ABSTRACT

The current study evaluated initial fixation strength of a bioabsorbable expansion bolt compared with interference screw fixation in anterior cruciate ligament reconstruction using a bone-patellar tendon-bone graft. Thirty calf tibial plateaus with adjacent patella and extensor ligaments were used. Bioabsorbable poly-L-lactide interference screws were used for graft fixation in Group I, titanium screws in Group II, and bioabsorbable poly-DL-lactide expansion bolts were used in Group III. The mean force-to-failure (+/- standard deviation) in the three groups was 487 +/- 205 N, 713 +/- 218 N, and 594 +/- 224 N, respectively. The differences between Groups I and II were significant. No statistical differences were found regarding stiffness. Graft damage was significantly less in Group III compared with screw fixation. The fixation concept of an expansion bolt shows similar fixation strength and less graft damage compared with the established interference screw fixation. Because of the total absence of torque forces in contrast to bioabsorbable screws, the risk of implant breakage is minimized.


Subject(s)
Absorbable Implants , Anterior Cruciate Ligament/surgery , Bone Screws , Animals , Cattle , Equipment Design , Prosthesis Failure
8.
Zentralbl Chir ; 128(4): 337-40, 2003 Apr.
Article in German | MEDLINE | ID: mdl-12700994

ABSTRACT

Anastomotic leakage is a serious complication in abdominal surgery. We report on two cases of spondylodiscitis L5/S1 following anastomotic leakage with fistula after low anterior rectal resection. Within five months after rectal resection two patients with massive back pain were admitted to our department. MRI established the diagnosis of spondylodiscitis. Ventral debridement, spondylodesis and protective stoma were performed. With this procedure we were able to achieve control of infection. There were no further complications in the follow-up. Stability of the spinal column was restored and massive back pain was entirely relieved. No signs of rectal cancer recurrence were seen in both cases during the observation period.


Subject(s)
Anastomosis, Surgical , Discitis/etiology , Ileostomy , Lumbar Vertebrae , Rectal Neoplasms/surgery , Rectum/surgery , Sacrum , Surgical Wound Dehiscence/complications , Colostomy , Discitis/diagnosis , Discitis/surgery , Follow-Up Studies , Humans , Lumbar Vertebrae/pathology , Lumbar Vertebrae/surgery , Magnetic Resonance Imaging , Male , Middle Aged , Rectum/pathology , Reoperation , Retrospective Studies , Sacrum/pathology , Sacrum/surgery , Spinal Fusion , Surgical Wound Dehiscence/diagnosis , Surgical Wound Dehiscence/surgery
9.
Injury ; 33(4): 357-65, 2002 May.
Article in English | MEDLINE | ID: mdl-12091034

ABSTRACT

Current concepts of treating thoraco-lumbar burst-compression injuries are based on posterior transpedicular fixation techniques which are angular stable. However, the long-term results of this approach are controversial due to inconsistent reports and due to a paucity of data on late outcome. In the present study we analyzed 50 patients retrospectively who had an unstable burst-compression injury at T 11-L 2 (type A 3 according to Magerl) without a neurological deficit. All fractures were stabilized by an internal fixator either with or without transpedicular spongiosa grafting. Patients were treated between 1991 and 1997. Follow-up times ranged from 36 to 103 months. Follow-up examinations collected occupational, subjective and clinical data (activity score, Hannover spine score) and included radiographic measurements. The latter were used to calculate the sagittal index (SI) which measures deformities of the fractured vertebral body, and the sagittal plane kyphosis (SPK) which additionally describes an eventual destruction of the affected intervertebral disc. Compared with the preinjury status, the percentage of subjects who were able to do physical labor was reduced by half at follow-up, and four times as many patients had a permanent disability. Correspondingly, activity scores and Hannover spine scores declined significantly. After the initial surgical correction SI remained stable until follow-up, whereas SPK decreased again towards pre-operative values indicating a progressive deformity of the intervertebral disc space. Clinical results did not correlate with radiographic results, and neither the time until follow-up nor the type of fracture n or the use of transpedicular bone grafting affected clinical or radiographic results significantly.


Subject(s)
Fracture Fixation, Internal/methods , Lumbar Vertebrae/injuries , Spinal Fractures/surgery , Thoracic Vertebrae/injuries , Adult , Aged , Bone Screws , Bone Transplantation , Female , Follow-Up Studies , Humans , Kyphosis/surgery , Lumbar Vertebrae/diagnostic imaging , Male , Middle Aged , Radiography , Retrospective Studies , Spinal Fractures/diagnostic imaging , Spinal Fractures/rehabilitation , Thoracic Vertebrae/diagnostic imaging , Treatment Outcome
10.
Zentralbl Chir ; 127(6): 514-8, 2002 Jun.
Article in German | MEDLINE | ID: mdl-12094277

ABSTRACT

This is a report on the treatment results of femoral neck fractures with a cemented (group 1) and cementless (group 2) type of hip prosthesis, resp. 72 patients were enrolled. 35 patients were treated with a cemented hip prosthesis (mean age: 78 years), and 37 patients with a cementless modular hip prosthesis (mean age: 77 years). In the cemented group we observed 5 cases of hypotension during insertion of the prosthesis in the femoral shaft. One of these patients required mechanical resuscitation during surgery. In the second group 3 cases of proximal femur fissure and one case of distal femoral fracture were recorded. One year after surgery 43 patients presented for follow up evaluation (cemented group: n = 24; cementless group: n = 19). Both groups revealed comparable results according to the Harris Hip Score (75 versus 78,3 points). No prosthesis loosening was observed in either group. In our view the cemented hip prosthesis is the treatment of choice for femoral neck fractures among the old and very old, if no stabile osteosynthesis can be performed. Patients with cardiopulmonary risk factors, however, may profit from cementless hip arthroplasty to avoid the well known cardiodepression during surgery.


Subject(s)
Bone Cements , Femoral Neck Fractures/surgery , Hip Prosthesis , Aged , Aged, 80 and over , Female , Femoral Neck Fractures/diagnostic imaging , Follow-Up Studies , Humans , Intraoperative Complications/etiology , Male , Postoperative Complications/etiology , Prospective Studies , Prosthesis Failure , Radiography , Risk Factors
11.
Z Orthop Ihre Grenzgeb ; 139(5): 452-7, 2001.
Article in German | MEDLINE | ID: mdl-11605299

ABSTRACT

UNLABELLED: PURPOSE/METHODS/PATIENTS: Calcitonin is a common treatment in patients suffering from Complex Regional Pain Syndrome Type 1 (CRPS I), although its effects are being controversially discussed. In a prospective study of 24 patients with CRPS I of the upper limb, we examined the tolerance of daily doses of 0.5 mg human calcitonin administered subcutaneously over 8 weeks. To assess the benefit of this therapy, the patients were clinically examined every second week. The results were compared to a consecutive group of 25 CRPS 1 patients who received only analgetics and physiotherapy. RESULTS: With regard to all examined parameters (spontaneous pain, grip strength, edema, hand function, systematic temperature difference), the patients treated with calcitonin showed an improvement during the observation time. However, a statistically significant difference to the control group was calculated only for the reduction of the edema (P < 0.01). 83% (20/24 patients) of the calcitonin-treated patients suffered from severe, mostly gastroenterological side-effects. Hence therapy had to be discontinued in 3 cases (13%). CONCLUSION: The therapy with calcitonin has the burden of numerous unpleasant side-effects and causes only a slight therapeutic improvement. Thus, calcitonin must only be prescribed with reservations for patients suffering from CRPS I.


Subject(s)
Calcitonin/administration & dosage , Reflex Sympathetic Dystrophy/drug therapy , Aged , Calcitonin/adverse effects , Drug Therapy, Combination , Female , Follow-Up Studies , Hand Strength , Humans , Male , Middle Aged , Motor Skills/drug effects , Pain Measurement , Prospective Studies , Reflex Sympathetic Dystrophy/diagnosis
12.
Allergy ; 56(9): 889-94, 2001 Sep.
Article in English | MEDLINE | ID: mdl-11551255

ABSTRACT

BACKGROUND: It has been shown that immediate-type allergy to natural rubber latex (NRL) affects predominantly health-care workers and infants with malformations requiring repeated medical procedures. Adult patients with multiple invasive procedures are not thought to be at an increased risk of NRL allergy. METHODS: A total of 325 consecutive adult inpatients (54.4+/-15.6 years; 219 men, 106 women) awaiting surgical or urologic procedures were assessed by questionnaire-based history (atopic diseases, number of previous standard operative or endoscopic procedures, intolerance to rubber products, and adverse reactions during medical care), by skin prick tests with different NRL test solutions, by measurement of NRL-specific IgE in the serum, and, if sensitization to NRL was found, by cutaneous challenge tests with NRL-containing material. Subjects were classified as sensitized to NRL if skin prick test reactions to NRL were positive or if NRL-specific IgE antibodies were found. NRL allergy was defined as NRL sensitization and immediate-type symptoms to NRL. RESULTS: Thirty-one of 325 (9.5%) subjects were found to be sensitized to NRL, 14/285 (4.9%) by skin prick testing and 23/323 (7.1%) by NRL-specific IgE antibodies in the serum. Four individuals (1.2%) were diagnosed as having clinically manifest NRL allergy, and another 27 (8.3%) were sensitized to NRL without symptoms to date. The frequency of previous invasive procedures was zero in eight patients, up to 10 in 245, 11-20 in 52, 21-30 in seven, and over 30 (up to 83) in 13 patients. No association was found between the number of invasive procedures and NRL sensitization without clinical symptoms. However, 3/4 patients with NRL allergy had undergone more than 30 interventions, and 1/4 had had 11 operations. Frequent invasive procedures (more than 10) were significantly associated with NRL allergy (P<0.001). Allergy or sensitization to NRL was associated with atopy (21/31 vs 87/294) (P<0.001). CONCLUSIONS: A remarkable percentage of unselected adult patients undergoing surgical procedures have allergy or sensitization to NRL. Repeated invasive treatment appears to be a risk factor for NRL allergy.


Subject(s)
Latex Hypersensitivity/epidemiology , Surgical Procedures, Operative/adverse effects , Adult , Aged , Aged, 80 and over , Antibodies/immunology , Female , Germany , Humans , Immunoglobulin E/immunology , Latex Hypersensitivity/immunology , Male , Middle Aged , Sensitivity and Specificity , Skin Tests
13.
Unfallchirurg ; 104(7): 622-8, 2001 Jul.
Article in German | MEDLINE | ID: mdl-11490955

ABSTRACT

Until now, no reports exist on the existence of femoral bone loss after hip arthroplasty using long-stem cementless prostheses in elderly patients. In a prospective evaluation the amount of bone loss (stress-shielding) after implantation of a long stem hip prosthesis in patients with femoral neck fractures (group A) or pertrochanteric femoral fractures (group B) was examined. Eleven patients (five from group A and six from group B) were treated with a long-stem modular hip prosthesis (MHP). Change of bone mass was evaluated using quantitative computed tomographie (QCT) immediately following and at six months (group A and B) and twelve months (group A) after implantation of the prosthesis. Clinical results, expressed with the modified Harris Hip Score, and relative changes of bone mass were compared with mean periprosthetic bone mass of the femur after operation. After implantation of the MHP, the maximum decrease of mean femoral bone mass was 19.1% at six months and 20.2% at twelve months for group A and 29.5% at six months for group B. Bone loss in the proximal periprosthetic area was higher than in the distal part. There was no correlation between baseline values of bone mass and the amount of stress-shielding or clinical outcome.


Subject(s)
Bone Density/physiology , Bone Diseases, Metabolic/diagnostic imaging , Femoral Neck Fractures/surgery , Femur/diagnostic imaging , Hip Fractures/surgery , Hip Prosthesis , Postoperative Complications/diagnostic imaging , Aged , Aged, 80 and over , Bone Cements , Equipment Failure Analysis , Female , Femoral Neck Fractures/diagnostic imaging , Follow-Up Studies , Hip Fractures/diagnostic imaging , Humans , Male , Middle Aged , Prosthesis Design , Risk Factors , Tomography, X-Ray Computed
14.
Clin Orthop Relat Res ; (380): 204-14, 2000 Nov.
Article in English | MEDLINE | ID: mdl-11064993

ABSTRACT

Between January 1, 1987, and December 31, 1997, an isoelastic polyacetal resin prosthesis was used in 50 patients with metastatic bone disease to reconstruct pathologic or impending fractures of the humeral diaphysis. Fifty-seven operations were performed, including seven revision surgeries. The patients were assessed before and after surgery for limb function and quality of life using a modified Karnofsky scale. The mean survival time was 440 days. Ninety-one percent of the operations resulted in restoration or improvement of quality of life. Limb function was good or excellent in more than 80% of the patients after surgery. Breaking of the implant (n = 3), loosening of the implant (n = 2), periprosthetic fracture (n = 1), hematoma (n = 2), infection (n = 1), and one radial nerve paralysis were the main complications. In the cases of implant failure, the prosthesis broke at the site of a locking screw that was inserted across the prosthetic shaft in the cementless implantation technique. This kind of complication could be avoided by using bone cement for implantation or additional plate osteosynthesis between the prosthesis and humeral shaft. The isoelastic diaphyseal prosthesis offers a promising method of treating patients with metastatic lesions of the humeral shaft.


Subject(s)
Bone Neoplasms/surgery , Fractures, Spontaneous/surgery , Humeral Fractures/surgery , Humerus , Prostheses and Implants , Adult , Aged , Aged, 80 and over , Bone Cements , Bone Neoplasms/complications , Bone Neoplasms/secondary , Fractures, Spontaneous/etiology , Humans , Humeral Fractures/etiology , Middle Aged , Postoperative Complications , Resins, Plant
15.
Zentralbl Chir ; 125(9): 756-62, 2000.
Article in German | MEDLINE | ID: mdl-11050757

ABSTRACT

Elastic intramedullary nailing represents a new surgical concept in the treatment of unstable shaft fractures in children. The present case control study wanted to examine the superiority of intramedullary nailing in comparison to conservative therapeutic concepts which had been applied so far. 13 children with forearm fractures who were treated initially by conservative measures were compared to 13 other children who received a primary intramedullary nailing. With femoral fractures, 12 children were included in each group. In each patient pair age, type and localisation of the fracture were comparable. During the observation period (until the termination of final therapeutic measures or until the third year after injury) we examined clinical variables and subjective findings. Both therapeutic concepts led to comparably good functional results. Also subjective judgement of the therapeutic success did not differ between groups. However, with intramedullary nailing of shaft fractures of the femur the mean hospital length of stay (7.0 +/- 3.5 days) was significantly shorter than with initial conservative treatment (36.5 +/- 2.2 days, P < 0.05). Irrespective of the localisation of the fracture intramedullary nailing required significantly less x-ray examinations during the observation period. These results suggest intramedullary nailing to be the procedure of choice to treat unstable forearm and femoral fractures in children.


Subject(s)
Femoral Fractures/surgery , Fracture Fixation, Intramedullary , Radius Fractures/surgery , Ulna Fractures/surgery , Adolescent , Bone Plates , Case-Control Studies , Casts, Surgical , Child , Child, Preschool , Female , Femoral Fractures/diagnostic imaging , Fracture Fixation, Internal , Fracture Healing/physiology , Humans , Length of Stay , Male , Postoperative Complications/diagnostic imaging , Radiography , Radius Fractures/diagnostic imaging , Retrospective Studies , Ulna Fractures/diagnostic imaging
16.
Arch Orthop Trauma Surg ; 120(7-8): 484-6, 2000.
Article in English | MEDLINE | ID: mdl-10968549

ABSTRACT

Cushing's syndrome is frequently associated with osteoporosis. Therefore, the incidence of osteoporotic spine fractures is significant. They are a rare cause of paraplegic syndromes. Additionally, epidural lipomatosis may occur in those patients. The combination of both fracture and lipomatosis may cause neurological deficit. A case of a young patient suffering from drug-induced Cushing's syndrome is reported. She developed progressive paraplegia. Radiographs demonstrated kyphosis of the thoracic spine from T7 to T9 and pathologic fractures. Urgent operation was planned to stabilize and decompress the spinal cord in the area of the kyphosis. Fortunately, magnetic resonance imaging (MRI) was conducted first. It confirmed pathologic fractures of T7-9 but also showed massive epidural fat extending from the level of T1 to T9. As suspected, laminectomy alone in the area of the fracture proved to be insufficient, as shown by myelography during operation. For treatment of paraplegia in this case of symptomatic epidural lipomatosis, an expanded laminectomy was necessary to remove all the epidural fat. Having undergone this procedure, the patient is now recovering from paraplegia. Our experience suggests that care should be taken before operative treatment of patients with pathological fractures in combination with Cushing's syndrome. In addition to vertebral fractures, epidural lipomatosis has to be taken into consideration. Those patients with neurological deficits have to be treated by an extensive laminectomy.


Subject(s)
Colitis, Ulcerative/drug therapy , Cortisone/adverse effects , Lipomatosis/chemically induced , Osteoporosis/chemically induced , Paraplegia/chemically induced , Spinal Cord Compression/chemically induced , Spinal Fractures/chemically induced , Thoracic Vertebrae/injuries , Adult , Cortisone/administration & dosage , Epidural Space , Female , Fractures, Spontaneous/chemically induced , Fractures, Spontaneous/diagnostic imaging , Fractures, Spontaneous/surgery , Humans , Kyphosis/chemically induced , Kyphosis/diagnostic imaging , Kyphosis/surgery , Lipomatosis/diagnostic imaging , Lipomatosis/surgery , Magnetic Resonance Imaging , Osteoporosis/diagnostic imaging , Osteoporosis/surgery , Paraplegia/diagnostic imaging , Paraplegia/surgery , Radiography , Spinal Cord Compression/diagnostic imaging , Spinal Cord Compression/surgery , Spinal Fractures/diagnostic imaging , Spinal Fractures/surgery , Spinal Fusion , Thoracic Vertebrae/diagnostic imaging , Thoracic Vertebrae/surgery
17.
Unfallchirurg ; 103(6): 444-51, 2000 Jun.
Article in German | MEDLINE | ID: mdl-10925646

ABSTRACT

From January 1997 to August 1998 all stable and nonstable trochanteric femoral fractures (n = 72) were treated routinely by gamma nail using the correct operative technique. Patients showing additional osteoarthritis of the hip in radiographs hip replacement was performed by a cementless modular femoral hip prostheses from January 1996 to August 1998 (n = 28). Follow up period was 6 to 18 months. Operation time and blood loss were higher using the prostheses. However complications and lethality (< 5%) were not different during postoperative course. In each group three operative technical complications occurred. Using a modified Harris Hip Score (without range of motion, contractions) the score was decreased non significant comparing both groups first of all in unstable fractures until follow up. In each group one revision (loosening of prostheses, excessive shortening of femoral neck) was necessary. Using the correct operative technique, the gamma nail proved to be a save device with good outcome. Outcome using modular prostheses is comparable to gamma nail. Therefore the use of modular prostheses is justified in case of osteoarthrosis and in some cases of very unstable fracture.


Subject(s)
Arthroplasty, Replacement, Hip , Bone Nails , Fracture Fixation, Intramedullary/instrumentation , Hip Fractures/surgery , Adult , Aged , Aged, 80 and over , Female , Follow-Up Studies , Hip Fractures/complications , Hip Fractures/diagnostic imaging , Humans , Male , Middle Aged , Osteoarthritis/complications , Postoperative Complications , Prospective Studies , Radiography , Time Factors , Treatment Outcome
18.
Intensive Care Med ; 26(2): 167-72, 2000 Feb.
Article in English | MEDLINE | ID: mdl-10784304

ABSTRACT

OBJECTIVE: Laboratory studies demonstrated significant detrimental effects of male sex-steroids (testosterone) on immune functions following hemorrhagic shock and soft-tissue trauma. Moreover, better survival of female mice subjected to severe sepsis was observed when compared to male animals. The aims of the present study were to evaluate whether or not gender differences regarding incidence and mortality of severe sepsis do exist in surgical intensive care patients and to elucidate the influence of patient age on incidence and mortality of severe sepsis/septic shock. DESIGN: Data base review of prospectively collected data from surgical intensive care patients. SETTING: Surgical intensive care unit of the department of surgery of a university hospital. PATIENTS: Prospectively collected data of 4,218 intensive care patients (2,709 male, 1,509 female). RESULTS: Significantly fewer female patients were referred to the intensive care unit (6.6 % vs 10.8 % of all patients; P < 0.05) leading to a significantly smaller proportion of female intensive care patients (35.8% vs 64.2%). No gender differences regarding number of failing organs or surgical procedure (exception vascular surgery) were observed in patients with and without severe sepsis/septic shock, indicating that the patients studied are comparable regarding general health prior to admission to SICU. Among all female patients referred to SICU only 7.6 % developed severe sepsis/septic shock, while 10.4% of all male patients suffered from severe sepsis or septic shock (P < 0.05). This gender difference results from a significantly lower incidence of severe sepsis/ septic shock in female patients between 60 and 79 years. No gender difference regarding mortality rates of severe sepsis/septic shock was observed (men 64.9 %, women 65.5%). CONCLUSIONS: Our results indicate a significantly smaller number of female patients requiring intensive care as well as a significantly lower incidence of severe sepsis/septic shock in female intensive care patients. Mortality from severe sepsis/ septic shock, however, is not affected by gender.


Subject(s)
Intensive Care Units , Sepsis/mortality , Adolescent , Adult , Age Factors , Aged , Aged, 80 and over , Female , Humans , Incidence , Length of Stay , Linear Models , Male , Middle Aged , Multiple Organ Failure/epidemiology , Prospective Studies , Sepsis/epidemiology , Sex Factors , Shock, Septic/mortality , Surgical Procedures, Operative
19.
Injury ; 31(5): 333-6, 2000 Jun.
Article in English | MEDLINE | ID: mdl-10775687

ABSTRACT

Modern concepts of treating thoracic diseases suggest more and more the use of minimally invasive thoracoscopic techniques to reduce morbidity and save costs. For treatment of specific lesions at the thoracic spine, several thoracoscopic procedures have been performed successfully. The present report examines the feasibility of thoracoscopic osteosynthesis in two patients with ventral hyperextension injuries and anterior instability of the thoracic spine. After initial correction of the anatomical deformity, autologous bone was harvested from the anterior iliac crest. Using a ventral, thoracoscopic approach, the main location of the ventral, damaged spinal segment was identified by the covering pleural haematoma. After endoscopic ventral bone grafting, osteosynthesis was performed, using dynamic compression plates, cardan drills and screw drivers. The perioperative course was uneventful, and follow up examinations after 3 years and 9 months, respectively, revealed an unchanged stable spinal segment. Our results show thoracoscopic osteosynthesis to be technically possible, with a potential for yielding satisfying long-term results.


Subject(s)
Fracture Fixation, Internal/methods , Spinal Fractures/surgery , Thoracic Vertebrae/injuries , Thoracoscopy , Aged , Aged, 80 and over , Bone Transplantation , Feasibility Studies , Female , Follow-Up Studies , Humans , Male , Radiography , Spinal Fractures/diagnostic imaging , Thoracic Vertebrae/diagnostic imaging , Thoracic Vertebrae/surgery
20.
J Orthop Trauma ; 14(8): 546-53, 2000 Nov.
Article in English | MEDLINE | ID: mdl-11149500

ABSTRACT

OBJECTIVE: To determine the biomechanical characteristics and potential clinical efficacy of a cementless modular femoral prosthesis consisting of a variable head (50 to 80 millimeters) and stem (length 120 to 280 millimeters, diameter 10 to 20 millimeters) component in patients with pertrochanteric femoral fracture. DESIGN: Finite element analysis (FEA) of different lengths and diameters of prosthesis components and first clinical prospective study in pertrochanteric femoral fracture. METHOD: Using a 3D-CAD program, a model of femoral cortical bone with a pertrochanteric fracture was created and combined with a model of the prosthesis. This model was transferred into an FEA program. After applying a torsion-bending load of 2,000 N (25 degrees, 45 degrees) on the prosthesis, stress distribution in the cortical bone was determined for different lengths (160 to 240 millimeters) and diameters (10 and 12 millimeters) of stem. PATIENTS: Twenty-eight patients with pertrochanteric fractures (very unstable or osteoarthritis) were treated with a modular hip arthroplasty. Complications, fracture healing, and results at first follow-up (average 13 months) were determined. RESULTS: FEA analysis indicated that reduction in stress was less when a prosthesis with a short stem was used. Shear stress in the interface bone/prosthesis was not affected by stem length. Prostheses with thin stems produced higher sheer stresses than those with thick stems. Results of FEA were used as the basis for clinical application of the device. None of the patients died, and all patients were able to walk, although some needed a cane or walker after surgery. There was no increase in thigh pain compared with reported pretrauma levels. Radiographs showed subsidence of up to 5 millimeters in 20 percent of patients. However, all but one prosthesis was stable at follow-up. Fracture healing was achieved in all patients. CONCLUSIONS: If proximal fixation of a femoral uncemented stem cannot be achieved, stem diameter should provide maximum cortical contact to reduce sheer stress. Longer stems do not necessarily provide additional stability. By using this prosthesis and selection method, a good outcome at first follow-up was observed.


Subject(s)
Activities of Daily Living , Arthroplasty, Replacement, Hip/instrumentation , Computer Simulation , Hip Fractures/therapy , Aged , Aged, 80 and over , Arthroplasty, Replacement, Hip/methods , Female , Follow-Up Studies , Hip Fractures/diagnosis , Humans , Male , Middle Aged , Models, Biological , Prospective Studies , Prosthesis Design , Prosthesis Failure , Prosthesis Fitting , Range of Motion, Articular/physiology , Stress, Mechanical , Treatment Outcome
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