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1.
Diana Rose E Ranoa; Robin L Holland; Fadi G Alnaji; Kelsie J Green; Leyi Wang; Richard L Fredrickson; Tong Wang; George N Wong; Johnny Uelmen; Sergei Maslov; Ahmed Elbanna; Zachary J Weiner; Alexei V Tkachenko; Hantao Zhang; Zhiru Liu; Sanjay J Patel; John M Paul; Nickolas P Vance; Joseph G Gulick; Sandeep P Satheesan; Isaac J Galvan; Andrew Miller; Joseph Grohens; Todd J Nelson; Mary P Stevens; P. Mark Hennessy; Robert C Parker; Edward Santos; Charles Brackett; Julie D Steinman; Melvin R Fenner Jr.; Kristin Dohrer; Kraig Wagenecht; Michael DeLorenzo; Laura Wilhelm-Barr; Brian R Brauer; Catherine Best-Popescu; Gary Durack; Nathan Wetter; David M Kranz; Jessica Breitbarth; Charlie Simpson; Julie A Pryde; Robin N Kaler; Chris Harris; Allison C Vance; Jodi L Silotto; Mark Johnson; Enrique Valera; Patricia K Anton; Lowa Mwilambwe; Stephen B Bryan; Deborah S Stone; Danita B Young; Wanda E Ward; John Lantz; John A Vozenilek; Rashid Bashir; Jeffrey S Moore; Mayank Garg; Julian C Cooper; Gillian Snyder; Michelle H Lore; Dustin L Yocum; Neal J Cohen; Jan E Novakofski; Melanie J Loots; Randy L Ballard; Mark Band; Kayla M Banks; Joseph D Barnes; Iuliana Bentea; Jessica Black; Jeremy Busch; Hannah Christensen; Abigail Conte; Madison Conte; Michael Curry; Jennifer Eardley; April Edwards; Therese Eggett; Judes Fleurimont; Delaney Foster; Bruce W Fouke; Nicholas Gallagher; Nicole Gastala; Scott A Genung; Declan Glueck; Brittani Gray; Andrew Greta; Robert M Healy; Ashley Hetrick; Arianna A Holterman; Nahed Ismail; Ian Jasenof; Patrick Kelly; Aaron Kielbasa; Teresa Kiesel; Lorenzo M Kindle; Rhonda L Lipking; Yukari C Manabe; Jade ? Mayes; Reubin McGuffin; Kenton G McHenry; Agha Mirza; Jada Moseley; Heba H Mostafa; Melody Mumford; Kathleen Munoz; Arika D Murray; Moira Nolan; Nil A Parikh; Andrew Pekosz; Janna Pflugmacher; Janise M Phillips; Collin Pitts; Mark C Potter; James Quisenberry; Janelle Rear; Matthew L Robinson; Edith Rosillo; Leslie N Rye; MaryEllen Sherwood; Anna Simon; Jamie M Singson; Carly Skadden; Tina H Skelton; Charlie Smith; Mary Stech; Ryan Thomas; Matthew A Tomaszewski; Erika A Tyburski; Scott Vanwingerden; Evette Vlach; Ronald S Watkins; Karriem Watson; Karen C White; Timothy L Killeen; Robert J Jones; Andreas C Cangellaris; Susan A Martinis; Awais Vaid; Christopher B Brooke; Joseph T Walsh; William C Sullivan; Rebecca L Smith; Nigel D Goldenfeld; Timothy M Fan; Paul J Hergenrother; Martin D Burke.
Preprint in English | medRxiv | ID: ppmedrxiv-21261548

ABSTRACT

In the Fall of 2020, many universities saw extensive transmission of SARS-CoV-2 among their populations, threatening the health of students, faculty and staff, the viability of in-person instruction, and the health of surrounding communities.1, 2 Here we report that a multimodal "SHIELD: Target, Test, and Tell" program mitigated the spread of SARS-CoV-2 at a large public university, prevented community transmission, and allowed continuation of in-person classes amidst the pandemic. The program combines epidemiological modelling and surveillance (Target); fast and frequent testing using a novel and FDA Emergency Use Authorized low-cost and scalable saliva-based RT-qPCR assay for SARS-CoV-2 that bypasses RNA extraction, called covidSHIELD (Test); and digital tools that communicate test results, notify of potential exposures, and promote compliance with public health mandates (Tell). These elements were combined with masks, social distancing, and robust education efforts. In Fall 2020, we performed more than 1,000,000 covidSHIELD tests while keeping classrooms, laboratories, and many other university activities open. Generally, our case positivity rates remained less than 0.5%, we prevented transmission from our students to our faculty and staff, and data indicate that we had no spread in our classrooms or research laboratories. During this fall semester, we had zero COVID-19-related hospitalizations or deaths amongst our university community. We also prevented transmission from our university community to the surrounding Champaign County community. Our experience demonstrates that multimodal transmission mitigation programs can enable university communities to achieve such outcomes until widespread vaccination against COVID-19 is achieved, and provides a roadmap for how future pandemics can be addressed.

2.
Preprint in English | medRxiv | ID: ppmedrxiv-21255827

ABSTRACT

Restricting in-person interactions is an important technique for limiting the spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Although early research found strong associations between cell phone mobility and infection spread during the initial outbreaks in the United States, it is unclear whether this relationship persists across locations and time. We propose an interpretable statistical model to identify spatiotemporal variation in the association between mobility and infection rates. Using one year of US county-level data, we found that sharp drops in mobility often coincided with declining infection rates in the most populous counties in spring 2020. However, the association varied considerably in other locations and across time. Our findings are sensitive to model flexibility, as more restrictive models average over local effects and mask much of the spatiotemporal variation. We conclude that mobility does not appear to be a reliable leading indicator of infection rates, which may have important policy implications.

3.
Article in English | WPRIM (Western Pacific) | ID: wpr-235780

ABSTRACT

Established in 1997, the European New Car Assessment Programme (Euro NCAP) provides consumers with a safety performance assessment for the majority of the most popular cars in Europe. Thanks to its rigorous crash tests, Euro NCAP has rapidly become an important driver safety improvement to new cars. After ten years of rating vehicles, Euro NCAP felt that a change was necessary to stay in tune with rapidly emerging driver assistance and crash avoidance systems and to respond to shifting priorities in road safety. A new overall rating system was introduced that combines the most important aspects of vehicle safety under a single star rating. The overall rating system has allowed Euro NCAP to continue to push for better fitment and higher performance for vehicles sold on the European market. In the coming years, the safety rating is expected to play an important role in the support of the roll-out of highly automated vehicles.


Subject(s)
Female , Humans , Male , Accident Prevention , Methods , Accidents, Traffic , Automobiles , Reference Standards , Europe , Program Evaluation , Safety , Reference Standards , Safety Management
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