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2.
Ann Biol Clin (Paris) ; 63(5): 535-9, 2005.
Article in French | MEDLINE | ID: mdl-16230292

ABSTRACT

We report a case of primary plasma cell leukaemia, with an absolute count of plasma cells of 53 Giga/L, diagnosed in a 83-year-old woman. The patient's condition improved, with no circulating plasma cells after 3 weeks of treatment, in response to the combination of thalidomide and dexamethasone administered for 5 days followed by thalidomide alone. The clinical presentation, the morphological, flow cytometric and pathophysiological characteristics of the plasma cell leukaemia and the treatment are summarised in this paper.


Subject(s)
Angiogenesis Inhibitors/therapeutic use , Leukemia, Plasma Cell/diagnosis , Thalidomide/therapeutic use , Aged, 80 and over , Anti-Inflammatory Agents/therapeutic use , Dexamethasone/therapeutic use , Female , Humans , Leukemia, Plasma Cell/drug therapy
4.
C R Acad Sci III ; 305(5): 161-4, 1987.
Article in French | MEDLINE | ID: mdl-3113681

ABSTRACT

Human fetuses (35-38 ws GA), exposed to a repeated pair of syllables, either [ba] [bi] or [bi] [ba], at 95 dB SPL when in a low heart rate variability state, display a significant heart rate deceleration. Changing the order of the syllables in the pair, [ba] [bi] becoming [bi] [ba] (or the reverse), induces a new cardiac deceleration. This suggests that fetuses demonstrate auditory discrimination abilities for speech units like syllables.


Subject(s)
Fetus/physiology , Heart Rate, Fetal , Speech Perception , Female , Humans , Phonetics , Pregnancy , Pregnancy Trimester, Third
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