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1.
Clín. investig. ginecol. obstet. (Ed. impr.) ; 35(6): 202-206, nov. 2008. tab
Article in Es | IBECS | ID: ibc-70366

ABSTRACT

Introducción: Estudios previos muestran que el incremento en la categoría del índice de masa corporal (IMC) se asocia a un mayor riesgo de complicaciones obstétricas. Objetivo: Investigar el impacto que tiene el incremento del IMC durante el embarazo en los resultados obstétricos en el Hospital Clínico de la Universidad de Chile. Material y métodos: Estudio retrospectivo que incluye a embarazadas atendidas en el hospital entre el año 2001 y 2006. Las mujeres con embarazos únicos fueron clasificadas en las distintas categorías de IMC. El incremento del IMC se calculó como la diferencia entre el IMC del inicio y el del final de la gestación. Para comparar las variables categóricas se usó el test exacto de Fisher y para las variables continuas el test de la t para comparación de 2 medias. Resultados: El estudio incluyó a 5.478 mujeres: 568(10,48%) no incrementaron su categoría de IMC y4.910 (89,51%) aumentaron su IMC en 1 o más categorías. El incremento del IMC se asoció a mayor riesgo de preeclampsia (p = 0,004) y operación cesárea (p =0,009) en las pacientes con sobrepeso, no así en las pacientes con normopeso al inicio del embarazo. Las pacientes obesas presentan mayor riesgo de preeclampsia(p = 0,008), diabetes gestacional (p < 0,001), operación cesárea (p < 0,001) e infección posparto (p = 0,009).Conclusión: El incremento en la categoría de IMC se asocia a un aumento del riesgo de complicaciones obstétricas (AU)


Background: Previous studies have shown that an increase in body mass index (BMI) is associated with a greater risk of obstetric complications. Aim: To investigate the effect of an increase in BMI category on obstetric outcomes in Hospital Clínic of the University of Chile. Material and methods: A retrospective study was conducted of women followed-up in the hospital from2001 to 2006. Women with singleton pregnancies were placed in standard BMI categories. Increases in BMI were calculated as the difference between initial BMI and that at delivery. Fisher’s exact test was used to compare categorical variables and the t test between two means was used for continuous variables. Results: This study included 5,478 women: 568(10.48%) had no change in BMI category and 4.910(89.51%) increased their BMI by >= 1 category. An increase in BMI category was associated with higher rates of preeclampsia (p = 0.004) and cesarean delivery(p = 0.009) in overweight women but not in women with a healthy weight at the beginning of pregnancy. Obese women had a higher risk of preeclampsia (p =0.008), gestational diabetes (p < 0.001), cesarean delivery(p < 0.001), and postpartum infection (p = 0.009).Conclusions: An increase in BMI category is associated with a greater risk of obstetric complications (AU)


Subject(s)
Humans , Female , Pregnancy , Adult , Body Mass Index , Gestational Age , Pregnancy Complications/diagnosis , Pregnancy Complications/epidemiology , Skinfold Thickness , Endometritis/complications , Endometritis/diagnosis , Pregnancy Complications/physiopathology , Pre-Eclampsia/complications , Diabetes, Gestational/complications , Chorioamnionitis/complications , Fetal Growth Retardation/complications , Retrospective Studies
3.
J Urol ; 156(1): 267-70, 1996 Jul.
Article in English | MEDLINE | ID: mdl-8648820

ABSTRACT

PURPOSE: We evaluated the fertilizing capacity of round spermatids recovered from varicocelized rabbits. MATERIALS AND METHODS: A left varicocele model was created in 5 rabbits (Group A). Four rabbits underwent a sham operation (Group B). After 3 months round spermatid nuclei were collected from the left testicle of each rabbit and injected into oocytes. Oocytes were cultured for 24 hours. RESULTS: The proportion of 2- to 4-cell stage embryos to the successfully injected oocytes was significantly lower in group A than in group B (p < 0.05). CONCLUSIONS: Our findings indicate a detrimental effect of varicocele on the fertilizing potential of round spermatid.


Subject(s)
Fertilization , Spermatids/physiology , Varicocele/physiopathology , Animals , Male , Rabbits
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