ABSTRACT
PURPOSE: To report a case series of three patients with bilateral uveal effusion syndrome (UES), treated conservatively with oral carbonic anhydrase inhibitors and topical prostaglandin analogues (PAs). METHODS: Three patients with bilateral UES were treated with the same initial therapy. Topical PA latanoprost 0.005% and acetazolamide 250 mg were administered in order to reduce intraocular pressure, improve uveoscleral outflow, and facilitate resolution of uveal effusion. RESULTS: The chorioretinal detachment resolved within 3 months in two reported patients while the third one underwent surgery on his left eye. After clinical improvement, further oral therapy with acetazolamide was stopped, while topical prostaglandins were continued for at least the next 3 months. All patients were free from recurrence during the follow-up period. CONCLUSION: Although the usually recommended UES therapy is partial or full-thickness sclerectomy, our case series showed apparent resolution of chorioretinal detachment in two patients on medical therapy alone. Conservative therapy may be the first step before the standard recommended surgical approach, but further studies are needed to verify the effectiveness of reported therapy.
Subject(s)
Acetazolamide/therapeutic use , Antihypertensive Agents/therapeutic use , Carbonic Anhydrase Inhibitors/therapeutic use , Choroid Diseases/drug therapy , Prostaglandins F, Synthetic/therapeutic use , Retinal Detachment/drug therapy , Uveal Diseases/drug therapy , Administration, Oral , Administration, Topical , Adult , Choroid Diseases/pathology , Drug Therapy, Combination , Female , Humans , Intraocular Pressure , Latanoprost , Magnetic Resonance Imaging , Male , Middle Aged , Retinal Detachment/pathology , Uveal Diseases/pathologyABSTRACT
AIMS: The aim of the study was to compare the accuracy of A-scan biometry and MRI for the measurement of axial length in silicone oil-filled eyes. METHODS: This was a prospective randomised study of 70 patients. Biometry was performed using MRI in 33 patients (MRI group) and A-scan echography in 37 patients (A-scan group). The difference between predicted and final refraction was measured and evaluated statistically. RESULTS: In patients with axial length >/=26 mm, the mean deviation of the final from predicted refraction was -1.23 (SD 0.67) D in the MRI group and -2.3 (SD 2.02) D in the A-scan group. The difference between these two groups was statistically significant (p = 0.02). In patients with axial length <26 mm, the mean deviation of the final from predicted refraction was -0.12 (SD 1.29) D in the MRI group and -0.33 (SD 1.39) D in the A-scan group. There was no statistical significance between the two groups (p = 0.629). CONCLUSION: For highly myopic patients MRI biometry was a more accurate measurement of axial length in silicone oil-filled eyes. A-scan and MRI biometry were comparably accurate in measuring axial length in patients with axial length <26 mm.
