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Med Tr Prom Ekol ; (5): 13-7, 2014.
Article in Russian | MEDLINE | ID: mdl-25335421

ABSTRACT

Left ventricle hypertrophy increases risk of cardiac failure and influences life expectancy. The authors demonstrated diagnostic reliability of genetic markers in evaluating left ventricle hypertrophy formation and their advantages over clinical signs, as outlines prognosis of diseases development on preclinical stage. Through genetic markers analysis with consideration of echo-cardiographic values of left ventricle myocardial weight, the authors determined genotypes associated with left ventricle hypertrophy development.


Subject(s)
Coal Mining , Heart Ventricles/pathology , Hypertrophy, Left Ventricular/genetics , Occupational Diseases/genetics , Amplified Fragment Length Polymorphism Analysis , DNA/genetics , Gene Frequency , Genetic Markers/genetics , Genotype , Humans , Hypertrophy, Left Ventricular/pathology , Male , Middle Aged , Occupational Diseases/pathology , Organ Size , Polymorphism, Restriction Fragment Length , Risk , Ukraine
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