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1.
Appl Nurs Res ; 73: 151721, 2023 10.
Article in English | MEDLINE | ID: mdl-37722789

ABSTRACT

BACKGROUND: During the SARS-CoV-2 pandemic, as in past disasters and emergencies, nurses around the world play an important role. What is more, the unprecedented pressure exerted by the pandemic on healthcare systems in every country brings big challenges to nurses, which may affect their well-being, work efficacy and job satisfaction. OBJECTIVE: The main objective of the presented studies was to describe anxiety factors related to the work of nurses during the SARS-CoV-2 pandemic; to assess the intensity of coronavirus anxiety and job satisfaction experienced by nurses at that time; to assess predictors of job satisfaction of nurses during the COVID-19 pandemic; to assess the differences in the intensity of job satisfaction and coronavirus anxiety depending on the selected variables related to their experiences during the COVID-19 pandemic. DESIGN: Anonymous questionnaire surveys were conducted online among the participants between 23 June 2020 and 23 March 2022 in Poland. PARTICIPANTS: 433 nurses from 15 Polish provinces were included in the studies (age range 22-68; M = 41.63). Nursing seniority M = 18.6. METHODS: The studies were based on: Satisfaction with Job Scale (SSP), Coronavirus Anxiety Scale (CAS), and a self-report structured questionnaire. RESULTS: The most respondents indicated that they were afraid of becoming infected with SARS-CoV-2 (25.4 %), transmitting infection to the family (22.4 %), becoming sick with COVID-19 and experiencing health complications (6.7 %) and of excessive work responsibilities and physical fatigue (6.5 %). Based on the bivariate correlation, it can be concluded that job satisfaction of the respondents during the COVID-19 pandemic was on an average level (M = 19.9); coronavirus anxiety was on an average level (M = 4.9), and stress at work was on a high level (M = 7.1). Coronavirus anxiety did not constitute statistically significant predictors of job satisfaction of subjects studied during the pandemic (SE = 0,048; ß = 0,05; p = 0.942). CONCLUSIONS: Coronavirus anxiety wasn't associated with job satisfaction of nurses directly. Job satisfaction of nurses during the COVID-19 pandemic was likely to be shaped by a range of different factors. TWEETABLE ABSTRACT: In Polish nurses coronavirus anxiety was average and wasn't associated with their job satisfaction.


Subject(s)
COVID-19 , Nurses , Humans , Young Adult , Adult , Middle Aged , Aged , Pandemics , Poland , Job Satisfaction , SARS-CoV-2 , Anxiety/epidemiology , Disease Outbreaks
2.
J Clin Med ; 11(20)2022 Oct 13.
Article in English | MEDLINE | ID: mdl-36294355

ABSTRACT

(1) Lockdown-related fatigue occurring during the COVID-19 pandemic is a complex problem that can be experienced in different social groups. The objective of the current study is to attempt to identify socio-demographic and lifestyle-related factors that determine the impact of fatigue on health in general as well as in physical, cognitive, and psychosocial terms and to determine whether, and to what extent, these were predictors of fatigue in nursing students during the COVID-19 pandemic. (2) The study was conducted by the diagnostic poll method between 20 March and 15 December 2021 among 894 nursing students at six Polish universities. To collect the data, a validated Modified Fatigue Impact Scale (MFIS) was used. (3) Students from the age group of ≤20 experienced a significantly greater impact of fatigue on health in general as well as in physical and cognitive terms. The study demonstrated a significant negative relationship between the year of study and the impact of fatigue on health in general terms (r = −0.12; p < 0.0001) and the analyzed health terms, on physical (r = −0.12; p < 0.0001), cognitive (r = −0.10; p < 0.002), and psychosocial (r = −0.07; p < 0.041). In predicting the impact of fatigue on health in general and physical terms, it was the variable related to a reduction in physical activity during the COVID-19 pandemic that had the greatest contribution, while for the cognitive and psychosocial functions, it was the number of meals consumed per day. (4) It is recognized that action is needed to reduce the impact of fatigue on student health by modifying the predictors related to student lifestyles.

3.
Nutrients ; 14(13)2022 Jun 25.
Article in English | MEDLINE | ID: mdl-35807819

ABSTRACT

(1) Background: An individual's health status can be perceived as a consequence of their health behaviours. This research aimed to determine the intensity of health-promoting behaviours and to identify factors determining the health behaviours of nursing students during the COVID-19 pandemic. (2) Methods: This study included 894 nursing students from six universities in Poland, and it was conducted between 20 March and 15 December 2021. A diagnostic survey was applied as the research method, and the data were collected using the Health Behaviour Inventory and the Satisfaction With Life Scale. (3) Results: Nearly half of the students participating in the study (48.43%) declared that the intensity of their general health behaviours was low. A positive and significant correlation (r = 0.426) was found between general health behaviours and satisfaction with life. A regression model demonstrated general satisfaction with life to be a predictor of taking up health-related behaviours (18%; ß = 0.34), as well as in terms of proper eating habits (4%; ß = 0.15), prophylactic behaviours (6%; ß = 0.21), positive mental attitudes (26%; ß = 0.44) and applied pro-health practices (10%; ß = 0.25). (4) Conclusions: Most nursing students showed low levels of health-promoting behaviours. More research is needed on health behaviours and their determinants among nursing students, as it may be important in explaining the mechanisms of health behaviour formation.


Subject(s)
COVID-19 , Students, Nursing , COVID-19/epidemiology , Health Behavior , Humans , Pandemics , Poland/epidemiology , Surveys and Questionnaires , Universities
4.
J Clin Med ; 11(11)2022 May 25.
Article in English | MEDLINE | ID: mdl-35683360

ABSTRACT

This study aimed to investigate the mediatory role of emotional control with respect to the control of anger, depression, and anxiety in the relationship between positive orientation and tiredness/fatigue occurring in a group of Polish nursing students during the COVID-19 pandemic. The study included 894 nursing students from six universities in Poland. A diagnostic survey was applied as the research method, and the data were collected using the Fatigue Severity Scale (FSS), the Courtauld Emotional Control Scale (CECS) and the Positive Orientation Scale (SOP). The mean participant age was 20.73 years (SD = 1.81). More than half of the students in the study showed a low level of positive orientation. Correlational analyses revealed a significant negative correlation between positive orientation and tiredness/fatigue experienced by the students participating in the study (r = −0.336; p < 0.001), and correlation between positive orientation and the overall emotional control index (r = −0.317; p < 0.001), and the indices of control of anger (r = −0.154; p < 0.01), depression (r = −0.376; p < 0.001), and anxiety (r = −0.236; p < 0.01). Analysis of the results also revealed the occurrence of significant, positive links between the controlled emotions and their components and the tiredness/fatigue experienced by nursing students. It is important to take action associated with the prevention of tiredness/fatigue among students and to reinforce a positive orientation and the capacity to control emotions to effectively minimize the effects of the COVID-19 pandemic on nursing students.

5.
Healthcare (Basel) ; 10(6)2022 May 24.
Article in English | MEDLINE | ID: mdl-35742023

ABSTRACT

(1) The COVID-19 pandemic is a global epidemic crisis situation with negative health consequences. This study aimed to determine the mediatory role of self-efficacy in correlations between dispositional optimism and loneliness (both general loneliness and social and emotional loneliness) among Polish nursing students during the COVID-19 pandemic. (2) The study involved 894 students from six Polish universities. A diagnostic survey was used as the research method, and the Scale for the Measurement of Loneliness Scale (DJGLS), Life Orientation Test (LOT-R), and the Generalized Self-Efficacy Scale (GSES) were used to collect data. (3) The mean subject age was 20.73 years (SD = 1.81). More than half (51.01%) of the respondents scored high on the GSES scale, indicating an individual's belief in the self-efficacy in coping with difficult situations and obstacles. However, 40.60% scored low on the LOT-R scale, indicating that the respondents were pessimistic. The mediation analysis revealed that self-efficacy plays a partial mediatory role in correlations between dispositional optimism and loneliness in general, social and emotional loneliness. (4) It is important to undertake loneliness prophylactic and prevention activities among nursing students and to develop personal resources, i.e., optimism and self-efficacy, to effectively offset the effects of the COVID-19 pandemic.

6.
BMC Nurs ; 20(1): 107, 2021 Jun 23.
Article in English | MEDLINE | ID: mdl-34162376

ABSTRACT

BACKGROUND: The nursing profession is associated with constant presence of difficult situations and stress, which arise from responsibility for the highest values - human life and health. With demographic changes in the society, the demand for nursing care increases. Looking after the health of nursing staff becomes a non-material investment in employees. One of the most important health potentials described in literature is the sense of coherence. It can significantly contribute to maintaining good health, modify one's functioning in a stressful working environment and influence the choice of strategies for coping with stress. AIM: The aim of the study was to describe the specific relationship between the sense of coherence and strategies for coping with stress in a group of professionally active nurses. METHODOLOGY AND METHODS: The study involved 91 nurses in central Poland, aged 22-52. The group was diversified in terms of: education, work system, marital status and place of residence. The study was conducted with the use of: Sense of Coherence Questionnaire SOC-29 and Inventory to Measure Coping Strategies with Stress - Mini-COPE. The study was conducted in accordance with the principles of scientific research set out in the Helsinki Declaration. RESULTS: The sense of coherence value in the test group was M = 134.24 (SD = 19.55). In stressful situations nurses most often used active strategies to cope with stress: Planning M = 2.10 (SD = 0.54), Seeking Emotional Social Support M = 1.95 (SD = 0.68) and Seeking Instrumental Social Support M = 1.95 (SD = 0.69), and the least frequently: Alcohol/Drug Use M = 0.28 (SD = 0.48). The level of the sense of coherence and its components differentiated the strategies of coping with stress used in the examined group of nurses. CONCLUSIONS: The research confirmed that the sense of coherence serves as a health potential in a stressful working environment - a high sense of coherence translate into better mental health, correct functioning in the working environment, and using adaptive strategies of coping with stress. Nurses with a stronger sense of coherence used more adaptive strategies to deal with stress than those with average or low levels.

7.
Nurs Open ; 8(6): 3403-3410, 2021 11.
Article in English | MEDLINE | ID: mdl-33942554

ABSTRACT

AIM: The main objective of this paper was to establish types of health status in the group of practicing nurses. DESIGN: Positive psychology defines human health as the underlying resource for all life activities, including professional work. Practicing nurses are exposed to a variety of professional pressures, most notably high-stress burden. Long-term functioning in conditions of work-related overburden and stress may compromise the health status of nurses and make them vulnerable to somatic or psychosomatic conditions. METHODS: In this study, we used original worksheets for collecting socio-economic data and health-related data, Orientation to Life Questionnaire (SOC-29), General Health Questionnaire (GHQ-28), Brief COPE Inventory (Mini-COPE) and the somatic symptom scale. K-means clustering analysis for cases was used to identify types of health status among the surveyed nurses. RESULTS: This survey discovered that specific types of health status can be distinguished among practicing nurses. The nurses represented various types of health status, levels of the sense of coherence and the use of stress management strategies.


Subject(s)
Nurses , Sense of Coherence , Health Status , Humans , Psychotherapy , Surveys and Questionnaires
8.
J Pers Med ; 11(3)2021 Mar 11.
Article in English | MEDLINE | ID: mdl-33799524

ABSTRACT

BACKGROUND: This study aimed to define the role and importance of patients' rights in personalized healthcare from the perspective of nursing students in Poland, Spain and Slovakia. METHODS: The research was carried out by means of a diagnostic survey, using the survey technique, with the participation of 1002 nursing students attending a full-time undergraduate study program at three European countries. The "Patients' rights" questionnaire was used as a research tool. The average age of students was 21.6 years (±3.4). The empirical material collected was subjected to a statistical analysis. RESULTS: The study demonstrated that 72.1% of nursing students from Spain, 51.2% from Poland and 38.5% from Slovakia believe that patients' rights are respected at a good level in their country. Significant intergroup differences (F = 67.43; p < 0.0001) were observed in the self-assessment of students' knowledge of patients' rights. The highest average values were obtained by students from Spain (3.54 ± 0.92), while 35.9% of students from Slovakia and 25.5% from Poland were quite critical and pointed to their low level of knowledge of patients' rights in their self-assessment. When ranking patients' rights related to respecting dignity, students from Spain obtained much higher average values (4.37 ± 0.92) than students from the other two countries. CONCLUSIONS: The level of students' knowledge of patients' rights and the respect for patients' rights by medical personnel is, in the opinion of the respondents, quite diverse and requires in-depth educational activities among nursing students at the university level in respective countries.

9.
Sci Rep ; 8(1): 7648, 2018 05 24.
Article in English | MEDLINE | ID: mdl-29795400

ABSTRACT

Direct phenological mismatch caused by climate change can occur in mammals that moult seasonally. Two colour morphs of the weasel Mustela nivalis (M. n.) occur sympatrically in Bialowieza Forest (NE Poland) and differ in their winter pelage colour: white in M. n. nivalis and brown in M. n. vulgaris. Due to their small body size, weasels are vulnerable to attacks by a range of different predators; thus cryptic coat colour may increase their winter survival. By analysing trapping data, we found that the share of white subspecies in the weasel population inhabiting Bialowieza Forest decreases with decreasing numbers of days with snow cover. This led us to hypothesise that selective predation pressure should favour one of the two phenotypes, according to the prevailing weather conditions in winter. A simple field experiment with weasel models (white and brown), exposed against different background colours, revealed that contrasting models faced significantly higher detection by predators. Our observations also confirmed earlier findings that the plasticity of moult in M. n. nivalis is very limited. This means that climate change will strongly influence the mortality of the nivalis-type due to prolonged camouflage mismatch, which will directly affect the abundance and geographical distribution of this subspecies.


Subject(s)
Biological Mimicry/physiology , Climate Change/mortality , Molting/physiology , Mustelidae/physiology , Adaptation, Biological/physiology , Animals , Color , Demography , Ecosystem , Forests , Phenotype , Poland , Predatory Behavior/physiology , Seasons , Snow
10.
Int J Occup Med Environ Health ; 31(1): 55-69, 2018 01 01.
Article in English | MEDLINE | ID: mdl-29052652

ABSTRACT

OBJECTIVES: The purpose of the study has been to describe functioning of single and mothers in relationships (married or in informal relationships) at work and verify if the declared degree of work satisfaction differentiates types of behavior at work and stress coping strategies in both groups of mothers. MATERIAL AND METHODS: The study was conducted on equal samples of single mothers (N = 186) and mothers from 2-parent families (N = 186) using Latack Coping Scale that measures work-related stress coping strategies, the AVEM (Arbeitsbezogenes Verhaltens- und Erlebensmuster - Work-Related Behavior and Experience Pattern) questionnaire, and a survey. It showed similarity between the studied groups in terms of the measured variables. RESULTS: There were considerable differences between single and married mothers in terms of support seeking strategies. The interaction of work satisfaction and the type of motherhood significantly differentiates (p = 0.03) the avoidance strategy of resignation. CONCLUSIONS: That strategy of resignation was more frequently used by single mothers with lower work satisfaction, who were distinctly different from those whose work satisfaction was higher, and from the mothers in relationships (married or in informal relationships) (regardless of the level of their work satisfaction). Int J Occup Med Environ Health 2018;31(1):55-69.


Subject(s)
Job Satisfaction , Marital Status , Mothers/psychology , Occupational Stress/epidemiology , Adaptation, Psychological , Adult , Female , Humans , Middle Aged , Stress, Psychological , Surveys and Questionnaires
11.
Clin Interv Aging ; 12: 315-323, 2017.
Article in English | MEDLINE | ID: mdl-28223789

ABSTRACT

BACKGROUND: Given the rising population of the elderly in modern societies, the concern for their good functioning poses a challenge for the 21st century medicine and social services. Senior citizens are at an increased risk of developing chronic conditions, which in turn increase discomfort associated with physiological processes of aging. Sensations of pain have a particular influence on the mentioned discomfort, and pain is prevalent among older people. Therefore, from the perspective of an elderly person and senior care, it is crucial to identify determinants of effective coping with chronic pain. OBJECTIVES: The aim of the research was to assess the relationship between a sense of coherence (SOC) and pain-coping strategies in chronically ill seniors. A total number of 188 individuals were included in the study, of whom 117 were female subjects and 71 were male subjects, with a mean age of 68.38 (standard deviation [SD] =6.35) years in the studied group. Subjects were sampled based on a diagnosis of a chronic medical illness with chronic pain as one of the major symptoms. METHODS: The Polish adaptation of the Orientation to Life Questionnaire (SOC-29) to assess an SOC, the Coping Strategies Questionnaire (CSQ) to assess pain-coping strategies, and the visual analog scale (VAS) to assess pain intensity were used in the study. RESULTS AND CONCLUSION: The mean score of respondents' SOC was 133.44 (SD =24.35). Among most common pain-coping strategies used by the respondents were prayer and hope, and the declaration of coping with pain while redefining pain was the least often used coping strategy in the studied group. Individuals with stronger SOC were less prone to catastrophizing and more often declared that they were coping with and could control and reduce pain.


Subject(s)
Adaptation, Psychological , Chronic Disease/psychology , Chronic Pain/psychology , Sense of Coherence , Aged , Female , Humans , Male , Middle Aged , Pain Measurement , Poland , Surveys and Questionnaires
12.
Psychiatr Pol ; 50(5): 1001-1014, 2016 Oct 31.
Article in English, Polish | MEDLINE | ID: mdl-27992892

ABSTRACT

OBJECTIVES: Understanding and fulfilling expectations of patients attending medical consultations is part and parcel of medical practice. Clinical context in which these expectations arise is crucial in assessing patients' expectations. The objective of this research was to assess patients' expectations of medical doctors depending on patients' mental state. METHODS: Patients attending GP consultations were examined. The research sample consisted of 219 patients, out of which 129 (59%) were female and 90 (41%) were male patients. The mean age of patients was 61 (SD = 9.80). The 28-item General Health Questionnaire (GHQ-28) and the Four Dimensional Symptom Questionnaire (4DSQ) were administered to assess patients' mental state and Patient Request Form (PRF) was used to assess patients' expectations of medical doctors. RESULTS: The study revealed that the youngest patients declared the highest anxiety and insomnia levels and that they differed significantly from the oldest patients. The sampled patients did not differ in terms of other mental state dimensions. It was also documented that younger patients had higher expectations of their medical doctors, required greater explanation of their medical condition and expected more emotional support. Both intensity and duration of somatic symptoms were particularly important in shaping those expectations. CONCLUSIONS: The research findings show the need for systematic assessment of mental state of patients attending medical consultations. Mental state and somatic symptoms intensity are essential indicators of patients' expectations of medical doctors.


Subject(s)
Mental Disorders/therapy , Mental Health/statistics & numerical data , Patient Satisfaction/statistics & numerical data , Physician-Patient Relations , Adult , Age Factors , Aged , Female , Humans , Male , Mental Disorders/psychology , Middle Aged , Primary Health Care , Surveys and Questionnaires
13.
Eur J Pharmacol ; 742: 47-54, 2014 Nov 05.
Article in English | MEDLINE | ID: mdl-25199965

ABSTRACT

Substantial variability of antiplatelet action is an important limitation of clopidogrel. The aim of this study was to evaluate time-related changes in determinants of clopidogrel responsiveness in patients after myocardial infarction. The study population comprised 191 consecutive patients treated with primary percutaneous coronary intervention for acute myocardial infarction. Follow-up visits were scheduled at 3, 6 and 9 months after discharge. ADP-induced platelet aggregation was tested with Multiplate Analyzer. Patients with ADP-PA>46.8U were defined as clopidogrel non-responders. The prevalence of clopidogrel non-responsiveness was highest during hospitalization and at 9 month follow-up visit, while it was lowest at 3 and 6 months after myocardial infarction (P=0.004). According to multivariate analysis, platelet count, mean platelet volume, concentration of hsCRP and leukocyte count influenced ADP-induced platelet aggregation in multiple assessment points. BMI, concentrations of hemoglobin, glycated hemoglobin, and BNP, hematocrit, adherence to medication, and patient׳s age were found to be independent predictors of high on-treatment ADP-induced platelet aggregation only at a single follow-up visit. Determinants of clopidogrel responsiveness in patients after myocardial infarction change within the long-term therapy. During hospitalization and early after discharge only biological factors affect ADP-induced platelet aggregation, while non-adherence to antiplatelet therapy may be a significant factor in determining clopidogrel non-responsiveness during late follow-up visits.


Subject(s)
Myocardial Infarction/blood , Myocardial Infarction/drug therapy , Platelet Aggregation Inhibitors/therapeutic use , Ticlopidine/analogs & derivatives , Adenosine Diphosphate/pharmacology , Aged , Clopidogrel , Female , Follow-Up Studies , Humans , Male , Medication Adherence , Middle Aged , Myocardial Infarction/therapy , Percutaneous Coronary Intervention , Platelet Aggregation/drug effects , Prospective Studies , Ticlopidine/therapeutic use , Time Factors
14.
Ann Transplant ; 19: 367-72, 2014 Jul 30.
Article in English | MEDLINE | ID: mdl-25073736

ABSTRACT

BACKGROUND: Sequels of chronic HCV infection are currently one of the most common indications for liver transplantation (LTx). Because HCV reinfection and allograft injury are inevitable, it may influence survival. Earlier studies have not reported higher mortality among HCV-infected patients, but cumulative data seem to contradict these findings. The aim of the study was to analyze post-LTx survival in HCV-positive patients in comparison with non-HCV-positive recipients and impact of antiviral treatment on survival in patients with recurrent HCV hepatitis. MATERIAL AND METHODS: Using data from the Polish national transplant registry, a retrospective cohort study of 327 patients who underwent LTx between 2000 and 2012 was performed. Cumulative 5-year mortality for HCV-positive patients vs. HCV-negative recipients and HCV-positive recipients treated with pegylated interferon/ribavirin vs. non-treated subjects was calculated using Kaplan-Meyer methodology. Mortality hazard rates were estimated using univariate proportional Cox models. RESULTS: Liver transplantation in HCV-positive vs. HCV-negative recipients was associated with significantly lower survival rate (cumulative 5-year survival 89.8 vs. 80.26%, respectively, p=0.04276) with a 5-year mortality HR of 1.99. Antiviral treatment improved survival irrespective of virological response (84.06% treated vs. 51.22% non-treated, p=0.00003). Univariate Cox HR for HCV treated vs. untreated patients is 0.18. Further improvement of survival was significantly associated with sustained virological response (100% vs. 77.67%, p=0.042). CONCLUSIONS: Our study confirms higher mortality risk among HCV-infected transplant recipients, improved survival related to the HCV treatment following graft reinfection, and positive association between the HCV treatment success and better survival.


Subject(s)
Antiviral Agents/therapeutic use , Hepatitis C, Chronic/drug therapy , Hepatitis C, Chronic/surgery , Liver Transplantation/mortality , Adolescent , Adult , Aged , Cohort Studies , End Stage Liver Disease/etiology , End Stage Liver Disease/mortality , End Stage Liver Disease/surgery , Female , Hepatitis C, Chronic/complications , Humans , Interferon alpha-2 , Interferon-alpha/therapeutic use , Kaplan-Meier Estimate , Male , Middle Aged , Poland/epidemiology , Polyethylene Glycols/therapeutic use , Proportional Hazards Models , Recombinant Proteins/therapeutic use , Retrospective Studies , Ribavirin/therapeutic use , Young Adult
15.
Curr Med Res Opin ; 30(5): 813-28, 2014 May.
Article in English | MEDLINE | ID: mdl-24393016

ABSTRACT

OBJECTIVES: To perform a systematic up-to-date review and critical discussion of potential clinical applications of cangrelor based on its pharmacologic properties and the main findings from randomized clinical studies. METHODS: A database search (PubMed, CENTRAL and Google Scholar) by two independent investigators, including proceedings from scientific sessions of ACC, AHA, ESC, TCT and EuroPCR, from January 1998 through December 2013. RESULTS: Cangrelor is a potent, intravenous, direct-acting P2Y12 antagonist with rapid onset and quickly reversible action. In contrast to ticagrelor, cangrelor's interaction with thienopiridines requires termination of cangrelor infusion before switching to clopidogrel or prasugrel. According to randomized trials, a cangrelor-clopidogrel combination is relatively safe and more effective than the standard clopidogrel regimen in both urgent and elective percutaneous coronary intervention (PCI) settings, with the advantage of this drug combination fully evident when the universal definition of myocardial infarction is applied. In contrast to available antiplatelet drugs with delayed onset and offset of action, its favorable properties make cangrelor a desirable agent for ad hoc elective PCI, high risk acute coronary syndromes treated with immediate coronary stenting and for bridging those surgery patients who require periprocedural P2Y12 inhibition. Current evidence on cangrelor therapy is limited by the lack of adequately powered studies assessing cangrelor co-administration either with prasugrel or ticagrelor, suboptimal design of some of the trials favoring cangrelor, potentially attenuated benefits with modern stent design, and finally, by the lack of survival advantage. CONCLUSIONS: With its pharmacokinetic and pharmacodynamic advantages, allowing consistent and strong P2Y12 inhibition, and with its rapid onset and swift reversal of action devoid of need for an antidote, cangrelor might improve clinical outcomes in clopidogrel-treated patients by reducing ischemic events, while maintaining a favorable safety profile. However, further studies, addressing the safety and efficacy of cangrelor on top of novel oral P2Y12 inhibitors, are warranted.


Subject(s)
Adenosine Monophosphate/analogs & derivatives , Coronary Artery Disease/drug therapy , Adenosine Monophosphate/pharmacology , Adenosine Monophosphate/therapeutic use , Animals , Humans , Randomized Controlled Trials as Topic
16.
Int J Endocrinol Metab ; 10(3): 537-42, 2012.
Article in English | MEDLINE | ID: mdl-23843816

ABSTRACT

BACKGROUND: Adaptation to a chronic somatic disease depends on a variety of factors, including belief in health locus of control. OBJECTIVES: Correlation between health locus of control and illness acceptance in patients with Graves-Basedow and Hashimoto diseases as well as correlation between health locus of control, illness acceptance, sex, and age. PATIENTS AND METHODS: THREE METHODS WERE APPLIED: Multidimensional Health Locus of Control Scale by K.A. Wallston, B.S. Wallston and R. DeVellis; the Acceptance of Illness Scale by B.J. Felton, T.A. Revenson, and G.A. Hinrichsena; and a personal questionnaire. Two groups were subject to the research: 68 patients with Graves-Basedow disease and 54 patients with Hashimoto disease. RESULTS: Patients with Graves-Basedow disease, women above all, have their health locus of control in other persons (P = 0,001) and are less inclined to accept their illness (P = 0,005) when compared to patients with Hashimoto disease. A statistically significant correlation occurred between the age of patients and external (i.e., in other persons) health locus of control. CONCLUSIONS: Beliefs in health locus of control and type of illness in female patient group are predictors of illness acceptance (P = 0,0009).

17.
Int J Occup Med Environ Health ; 24(3): 256-66, 2011 Sep.
Article in English | MEDLINE | ID: mdl-21833694

ABSTRACT

OBJECTIVES: This paper is a report on the relationship between a sense of coherence (and its components) and work related patterns of behaviour in the group of nurses. MATERIALS AND METHOD: Data were collected by two questionnaires (Antonovsky's Orientation Questionnaire and Work Related Patterns of Behaviour and Experience Questionnaire) in the sample of 331 volunteer nurses employed in three Polish general care hospitals. RESULTS: The analysis of r-Pearson's correlation and the linear multiple regression analysis revealed a strong relationship between the sense of coherence and healthy type of behaviour, and a strong negative relationship with a burnout type of behaviour. CONCLUSION: The results obtained in this study provide grounds for the conclusion that the sense of coherence correlates with healthy functioning at work in the group of nurses.


Subject(s)
Adaptation, Psychological , Nursing Staff, Hospital/psychology , Sense of Coherence , Workplace/psychology , Adult , Burnout, Professional/psychology , Female , Humans , Middle Aged , Young Adult
18.
Przegl Lek ; 66(10): 783-5, 2009.
Article in Polish | MEDLINE | ID: mdl-20301936

ABSTRACT

Nicotine addiction is a huge social problem and at the same time it is one of the most popular and well-known risk factor in many diseases which can be eliminated. The aim of the study was to asses differences in the health behaviours from regard on type the dependence of from nicotine. In the study participated 221 (males and females) persons dependent on nicotine. In this study applied: Inventory of Health Behaviour--IZZ by Juczynski and Fagerström Test for Nicotine Dependence. Received results show that health behaviours are practiced more often by women and it is not dependent on the level of their addiction. Among men the type of nicotine addiction differentiates the frequency of applying the healthy behaviours. Pharmacological addicts have fewer tendencies to behave in healthy way.


Subject(s)
Health Behavior , Tobacco Use Disorder/epidemiology , Adult , Female , Humans , Male , Poland/epidemiology , Sex Distribution , Sex Factors
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