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Farm Hosp ; 27(2): 93-100, 2003.
Article in Spanish | MEDLINE | ID: mdl-12717564

ABSTRACT

Arsenic trioxide has drawn renewed interest in onco-haematological therapy. Based on a number of studies quoted in this paper, it has been approved by FDA and EMEA for remission induction and consolidation therapy of acute promyelocytic leukaemia in patients refractory to treatment using trans-retinoic acid and anthracyclines. In addition to briefly discuss available therapeutic resources against this disease, this review attempts to provide an in-depth view of this drugâs characteristics and efficacy, as shown in several studies.


Subject(s)
Antineoplastic Agents/therapeutic use , Arsenicals/therapeutic use , Leukemia, Promyelocytic, Acute/drug therapy , Oxides/therapeutic use , Antineoplastic Agents/administration & dosage , Antineoplastic Agents/adverse effects , Antineoplastic Agents/pharmacology , Arsenic Trioxide , Arsenicals/administration & dosage , Arsenicals/adverse effects , Arsenicals/pharmacology , Clinical Trials as Topic , Humans , Oxides/administration & dosage , Oxides/adverse effects , Oxides/pharmacology
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