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1.
Probl Endokrinol (Mosk) ; 70(2): 94-102, 2023 Oct 18.
Article in Russian | MEDLINE | ID: mdl-38796766

ABSTRACT

IgG4-related disease is a rare chronic pathology manifested by lymphoplasmacytic infiltration of one or more organs, the formation of storiform fibrosis, tissue edema, and an increase of IgG4 in the blood. This disease was singled out as an independent nosological unit only in 2001. The incidence is less than 1 in 100,000 people per year. Almost any organ can be affected in IgG4-related disease. The association of Riedel's thyroiditis with IgG4 was established in 2010. Riedel's thyroiditis is an extremely rare inflammatory disease of the thyroid gland, which diagnosis is complicated by an atypical course and the absence of characteristic symptoms. Less than 300 clinical cases of the disease have been described in the world, only two from them were in children. This article presents a clinical case of a 6-year-old boy with Riedel's thyroiditis.


Subject(s)
Immunoglobulin G4-Related Disease , Immunoglobulin G , Humans , Child , Male , Immunoglobulin G/blood , Immunoglobulin G/immunology , Immunoglobulin G4-Related Disease/pathology , Immunoglobulin G4-Related Disease/diagnosis , Immunoglobulin G4-Related Disease/drug therapy , Thyroid Gland/pathology , Thyroid Gland/immunology , Thyroiditis, Autoimmune/immunology , Thyroiditis, Autoimmune/diagnosis , Thyroiditis, Autoimmune/pathology , Thyroiditis, Autoimmune/complications , Thyroiditis, Autoimmune/blood
2.
Urologiia ; (4): 91-94, 2019 Sep.
Article in Russian | MEDLINE | ID: mdl-31535812

ABSTRACT

The presented clinical case of a girl with a salt-wasting form of congenital adrenal hyperplasia in combination with chronic recurrent infection and lower urinary tract dysfunction demonstrates the need to change conventional two-staged approach to surgical feminization in favor of a one-stage intervention in order to prevent a progression of genitourinary complications. After controlling for the underlying condition, the one-stage feminization was performed, including modified tightening introitoplasty using a Passerini-Glazel flap and a correction of hypertrophic clitoris and labia minora. Good short- and long-term results were achieved.


Subject(s)
Adrenal Hyperplasia, Congenital , Disorders of Sex Development , Hypospadias , Female , Humans , Male , Sexual Development , Surgical Flaps
3.
Urologiia ; (4): 85-91, 2007.
Article in Russian | MEDLINE | ID: mdl-17915454

ABSTRACT

The authors analyse treatment of 3235 patients with prepuce pathology aged from 8 days to 16 years, the results of the treatment of preputial sac pathology; describe clinical manifestations of phimosis (physiological, hypertrophic, cicatricial) in children; formulate treatment policy, indications and contraindications for conservative and surgical treatment; provide practical recommendations on hygiene and care for infant and young age boys.


Subject(s)
Foreskin/pathology , Foreskin/physiopathology , Phimosis/pathology , Phimosis/physiopathology , Phimosis/therapy , Adolescent , Adolescent Health Services/standards , Child , Child, Preschool , Humans , Infant , Infant Care/standards , Infant, Newborn , Male , Skin Care/methods , Skin Care/standards
4.
Urologiia ; (1): 31-6, 2001.
Article in Russian | MEDLINE | ID: mdl-11233229

ABSTRACT

14 boys with balanic hypospadia (BH) and 23 boys with coronal hypospadia (CH) aged 9 months to 15 years were operated in 1997-2000. For 13 boys this operation was meatoglanuloplasty (MAGPI) by J. Duckett. Complications occurred in 4 boys: retraction (downwards) of the meatus (n = 2), urethral stenosis and urinary fistula (n = 2). 24 boys have undergone modified MAGPI operation. The modification consists in extended mobilization of the lateral parts of the head with longitudinal consecutive incisions along the head margin into the spongy bodies. The head is closed by suturing its mobilized margins with two rows of interrupted monofilamentous (PDS, prolene) sutures above the urethra. A variant of saving foreskin is possible when partial separation of the internal and external layers is made bilaterally with consecutive circular closure of the preputial sac. Phimosis is prevented by a relief longitudinal incision along the internal foreskin and transverse suturing. The patients were followed up for 2 months to 1.5 years. The original operation MAGPI provided good cosmetic and functional results in 9 boys(69.2%), satisfactory in 2 boys(15.4%), unsatisfactory also in 2 boys(15.4%). The modified MAGPI operation provided only good cosmetic and functional results. Thus, the proposed modification (MAGPI-Duckett) ensures a more reliable variant of meatoglanuloplasty in balanic and coronal hypospadia irrespective of the size and shape of the head, presence of the scaphoid fossa or meatostenosis. These additional procedures helped to reduce the number of postoperative complications and improved cosmetic and functional results.


Subject(s)
Hypospadias/surgery , Penis/abnormalities , Plastic Surgery Procedures , Urologic Surgical Procedures, Male/methods , Adolescent , Child , Child, Preschool , Humans , Infant , Male , Penis/surgery , Retrospective Studies , Suture Techniques
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