ABSTRACT
The report contains the results of a palrographic study of the blood and CSFin 726 patients with different disorders of the nervous system. It was possible to demonstrate statistically significant differences in the degree of expressiveness of the Brdicki filtrate test in benign and malignant tumors. The authors also established the significance of a differential diagnostical test, permitting to distinguish a vascular (pseudotumor) brain disorder from a tumorousone. A polarographic analysis of the CSF may be used as a supplementary diagnostical method in tumors of the CNS. The role of sulfhydrile groups in the mechanism of the polarographic effect is discussed.
Subject(s)
Nervous System Diseases/diagnosis , Brain Neoplasms/diagnosis , Cerebrovascular Disorders/diagnosis , Diagnosis, Differential , Humans , Neoplasm Metastasis , Polarography , Sulfhydryl Compounds/blood , Sulfhydryl Compounds/cerebrospinal fluidABSTRACT
The authors conducted a polygraphic study of the blood plasma proteins in 102 patients with brain tumors of a different histological structure. The data depicted a moderate statistically significant increase of the first and second catalytical waves in benign tumors and a significant (1.5 times more) increase in malignant and metastatical tumors in comparison to the data achieved in donors. This method can be used as a supplementary one for differential diagnostical purposes in the practice of neurooncology.
