ABSTRACT
Rhabdomyosarcomas (RMS) are among the most common soft-tissue tumors in children. These tumors are derived from mesenchymal tissue with a tendency toward myogenic differentiation that probably originates from immature and highly invasive satellite cells associated with the embryogenesis of skeletal muscle. Some of these tumors are associated with high rates of recurrence and metastasis. The diagnosis is made by microscopic analysis and auxiliary techniques such as immunohistochemistry, electron microscopy, cytogenetic analysis, and molecular biology. We report here a case of orofacial RMS in a 4- year-old child and provide an updated review of the literature, focusing mainly on the clinicopathological aspects, diagnosis and treatment of RMS of the head and neck.
Subject(s)
Facial Neoplasms/diagnosis , Mouth Neoplasms/diagnosis , Rhabdomyosarcoma/diagnosis , Child, Preschool , Humans , MaleABSTRACT
Rhabdomyosarcomas (RMS) are among the most common soft-tissue tumors in children. These tumors are derivedfrom mesenchymal tissue with a tendency toward myogenic differentiation that probably originates from immatureand highly invasive satellite cells associated with the embryogenesis of skeletal muscle. Some of these tumors areassociated with high rates of recurrence and metastasis. The diagnosis is made by microscopic analysis and auxiliarytechniques such as immunohistochemistry, electron microscopy, cytogenetic analysis, and molecular biology. Wereport here a case of orofacial RMS in a 4-year-old child and provide an updated review of the literature, focusingmainly on the clinicopathological aspects, diagnosis and treatment of RMS of the head and neck (AU)
Subject(s)
Humans , Male , Child, Preschool , Facial Neoplasms/diagnosis , Mouth Neoplasms/diagnosis , Rhabdomyosarcoma/diagnosisABSTRACT
Myiasis is a term derived from the Greek word "myia", meaning invasion of vital tissue of humans or other mammals by fly larvae. The deposited eggs develop into larvae, which penetrate deep structures causing adjacent tissue destruction. It is an uncommon clinical condition, being more frequent in underdeveloped countries and hot climate regions, and is associated with poor hygiene, suppurative oral lesions, alcoholism and senility. Its diagnosis is made basically by the presence of larvae. This paper reports a case of oral and maxillofacial myiasis involving 273 larvae in a patient with epidermoid carcinoma without physical or neurological deficiency. The patient's management was antisepsis, larval removal and general care, before death after three months.
