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Vopr Virusol ; 39(6): 278-81, 1994.
Article in Russian | MEDLINE | ID: mdl-7716925

ABSTRACT

The composition of African swine fever virus (ASFV) glycoproteins was studied. Isolate-specific major gp 110-140 was identified by radioimmunoprecipitation in lysate of porcine bone marrow cells infected with hemadsorbing virus strains. Carbohydrates constitute about 50% of the total mass of gp 110-140. A quantitative method is proposed for identification of the serologic relationships between ASFV hemadsorbing strains. A possible role of ASFV glycoprotein carbohydrates in the hemadsorption, virulence, and immunogenicity is discussed.


Subject(s)
African Swine Fever/metabolism , Glycoproteins/metabolism , Viral Proteins/metabolism , African Swine Fever Virus/immunology , African Swine Fever Virus/metabolism , African Swine Fever Virus/pathogenicity , Animals , Antigens, Viral/immunology , Binding Sites , Carbohydrates/analysis , Cells, Cultured , Glycoproteins/chemistry , Glycoproteins/immunology , Glycosylation , Radioimmunoprecipitation Assay , Swine , Viral Proteins/chemistry , Viral Proteins/immunology , Virulence
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