ABSTRACT
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Subject(s)
Humans , Male , Aged , Coronavirus Infections/therapy , Lung Neoplasms/therapy , Carcinoma, Squamous Cell/therapy , Coronavirus Infections/diagnosis , Lung Neoplasms/diagnosis , Carcinoma, Squamous Cell/diagnosis , Prognosis , Radiography, Thoracic , Treatment OutcomeSubject(s)
COVID-19/diagnosis , Carcinoma, Squamous Cell/surgery , Lung Neoplasms/surgery , SARS-CoV-2 , Acute Kidney Injury/diagnosis , Aged , COVID-19/complications , COVID-19/therapy , COVID-19 Nucleic Acid Testing , Carcinoma, Squamous Cell/complications , Carcinoma, Squamous Cell/diagnostic imaging , Ex-Smokers , Humans , Lung Neoplasms/complications , Lung Neoplasms/diagnostic imaging , Patient Transfer/methods , Thoracic Surgery, Video-AssistedABSTRACT
Amyloid elastosis is a rare form of cutaneous amyloidosis characterized histologically by the deposition of amyloid-coating elastic fibers of the skin. To date, only 4 cases have been reported, all of them in the setting of systemic amyloidosis. We present the first case of primary cutaneous localized amyloid elastosis.
Subject(s)
Amyloidosis/pathology , Facial Dermatoses/pathology , Adult , Amyloid/metabolism , Amyloidosis/genetics , Amyloidosis/metabolism , Amyloidosis/therapy , Elastic Tissue/pathology , Facial Dermatoses/genetics , Facial Dermatoses/metabolism , Facial Dermatoses/therapy , Gene Rearrangement , Humans , Immunoglobulin Heavy Chains/genetics , Male , Radiotherapy, Adjuvant , Treatment OutcomeABSTRACT
Adenolipoma is a rare microscopic variant of cutaneous lipoma composed of large lobules of mature adipocytic tissue admixed with eccrine ducts and glands. We report a new case of cutaneous adenolipoma, and the first showing an apocrine cystic glandular component. This lesion may not be a specific entity, and could represent entrapment of epithelial structures within a lipoma.
Subject(s)
Apocrine Glands/pathology , Lipoma/pathology , Skin Neoplasms/pathology , Adult , Apocrine Glands/metabolism , Diagnosis, Differential , Female , Humans , Immunohistochemistry , Lipoma/metabolism , S100 Proteins/metabolism , Skin Neoplasms/metabolismABSTRACT
Although spindle cell carcinoma (SC) is a common neoplasm in the oral cavity, upper respiratory tract, and other head and neck areas, its occurrence in the vulva is rare. We report a case of this rare condition with immunohistochemical, ultrastructural, and human papillomavirus (HPV) testing. The neoplastic cells were positive for vimentin, keratins (AE1-AE3, keratin 902, and keratin 903), and epithelial membrane antigen. Ultrastructurally, they showed primitive junctions and tonofilaments. HPV testing by polymerase chain reaction was negative. In addition, we review the clinicopathologic findings of the four well-documented cases of vulvar SC that have been reported previously in the English language literature.