ABSTRACT
We estimated serum insulin-like growth factor-1 (IGF-1) level to correlate for development of retinopathy of prematurity (ROP) in serum from 15 premature infants. 73% of the infant developed Stage 1 ROP and the rest develop Stage 2. Zone III involvement never progress beyond Stage 1, and Zone II beyond Stage 2. Severity of ROP could not be related to the level of IGF-1. All cases develop ROP of Stage 1 and 2 irrespective of serum IGF-1.
Subject(s)
Biomarkers/blood , Insulin-Like Growth Factor I/metabolism , Retinopathy of Prematurity/blood , Enzyme-Linked Immunosorbent Assay , Female , Follow-Up Studies , Gestational Age , Humans , Infant, Newborn , Male , Ophthalmoscopy/methods , Prognosis , Prospective Studies , Retinopathy of Prematurity/diagnosis , Severity of Illness Index , Video RecordingABSTRACT
VEGA-A concentration was measured in undiluted vitreous fluid samples were taken at the start of vitrectomy procedure from 9 new cases of proliferative diabetic retinopathy and 8 non-diabetic patients. A positive correlation was found between VEGF-A levels and blood sugar and HgbA1c levels of patients with proliferative diabetic retinopathy.
