ABSTRACT
We studied two cases of mandibular radicular cysts lined in part with ciliated epithelium by examining them histopathologically and ultrastructurally. In addition, we examined the incidence of cilia in 205 radicular cysts in the biopsy materials collection in our Department. No other mandibular cysts having cilia in the lining were found, and so these were very rare. Regarding the histogenesis of the cilia, we consider that the development of cilia in mandibular radicular cysts may be due to true metaplasia rather than to adaptation which is a functional requisite of the lining epithelium for the unique cystic environment.
Subject(s)
Mandibular Diseases/pathology , Radicular Cyst/ultrastructure , Adult , Aged , Cilia/ultrastructure , Epithelium/ultrastructure , Humans , Male , Microscopy, Electron, Scanning TransmissionABSTRACT
Lipoma is an uncommon tumour in the oral cavity. Infiltrating lipoma is extremely rare. An infiltrating lipoma of the mental region in a 48-year old woman is reported. Wide myectomy was performed, and follow-up showed excellent healing without recurrence.
Subject(s)
Chin/surgery , Facial Neoplasms/pathology , Lipoma/pathology , Facial Muscles/surgery , Facial Neoplasms/surgery , Female , Humans , Lipoma/surgery , Middle AgedABSTRACT
Gelatin capsules containing squalane partially purified bone morphogenetic protein (BMP) complex were placed on the perimuscular membrane of rats. Two kinds of control, gelatin capsules containing only BMP and those bearing squalane only, were used. The embedded areas were histopathologically examined at 3 and 6 wk after the operation. The observations revealed that the squalane/BMP complex elicited wide heterotopic bone formation with bone marrow tissue, suggesting that squalane is a possible carrier of BMP for clinical applications.
Subject(s)
Proteins/administration & dosage , Squalene/analogs & derivatives , Animals , Bone Morphogenetic Proteins , Capsules , Cattle , Drug Carriers , Female , Growth Substances/administration & dosage , Rats , Rats, Sprague-Dawley , Squalene/administration & dosageABSTRACT
It is widely accepted that radicular cysts (apical periodontal cysts) are commonly lined with stratified squamous epithelium without keratin formation. However, we identified a case of maxillary radicular cyst with remarkable keratinization and atypical proliferation of the lining epithelium among the 207 radicular cyst cases seen at our department. Histopathological and clinical findings of these cysts were reviewed.
Subject(s)
Maxillary Diseases/pathology , Radicular Cyst/pathology , Cell Division , Cytoplasmic Granules/ultrastructure , Epithelium/pathology , Fibrosis , Granulation Tissue/pathology , Humans , Hyalin , Keratins , Keratosis/pathology , Male , Middle AgedABSTRACT
A developmental bone substitute, composed of a chitosan-bonded hydroxyapatite paste and having various possible applications in medical and dental treatments, was evaluated with regard to its osteoconductive properties. Radiographic examination revealed that a bone-like irregular radiopacity appeared in the region of the embedded paste. This was judged histopathologically as the formation of bone tissue with chondral tissue. These data suggest that the paste has osteoconductive properties, and may, therefore, prove clinically useful as a bioactive bone substitute.
Subject(s)
Biocompatible Materials , Bone and Bones/pathology , Hydroxyapatites , Animals , Bone and Bones/diagnostic imaging , Female , Ointments , Rabbits , RadiographyABSTRACT
Histopathologic, immunohistochemical, and ultrastructural features of the giant cells appearing in the tissue surrounding an ameloblastoma are presented. These giant cells exhibited strong activity of a highly stable form of acid phosphatase, and were positive for alpha-1-antichymotrypsin. Ultrastructurally, the cytoplasm of the giant cells contained numerous mitochondria, and the cell membrane was comparatively smooth. Therefore, it is proposed that these multinucleated giant cells are reactive to the invasion of ameloblastoma and are histiocytic in origin.
