ABSTRACT
A case of persistence of the right venous sinus valve that on echocardiographic examination simulated right atrial myxoma is reported in a patient with total abnormal pulmonary venous return in the coronary sinus. Echocardiography showed a mobile, pedunculated mass present in systole in the right atrium that shifted to diastole in the right ventricle, highly suggestive of right atrial myxoma. The right ventricle also showed a volume overload and a space without echoes behind the left atrium. A membrane was encountered in the right atrium at surgery. This was removed and the venous return corrected.
Subject(s)
Echocardiography , Heart Defects, Congenital/diagnosis , Heart Neoplasms/diagnosis , Myxoma/diagnosis , Diagnosis, Differential , Female , Humans , InfantSubject(s)
Arrhythmias, Cardiac/drug therapy , Propafenone/therapeutic use , Adolescent , Child , Child, Preschool , Electrocardiography , Female , Humans , Male , Monitoring, PhysiologicSubject(s)
Heart Function Tests , Heart Ventricles/physiopathology , Kidney Failure, Chronic/physiopathology , Renal Dialysis , Adolescent , Child , Child, Preschool , Female , Humans , MaleABSTRACT
Pharmacological clinical studies about beta-blocking agents provide profound insights into the effects of these kinds of drugs in adults. Very little research on children has been done up to now. The hydroalcoholic solution of a beta-blocking agent (Visken Sandoz) facilitated this research on children. This paper investigates the effects of a beta-blocking agent in 19 healthy children aged between 5 and 13 years: arterial blood pressure, heart rate, systolic and diastolic parameters were controlled. The children were examined before and after a 10 day therapeutical cycle in which Pindolol 250 gamma/kg/die was administered. Statistically significant variations were obtained for TD, TT, TT/TET, QTc, but no variation for heart rate, TET, SM, QA2, diastolic parameters and arterial blood pressure. It is supposed that negative chronotropic effect and hypotensive activity were found only in patients with an altered cardiac rate and with an altered arterial blood pressure respectively. The kinetics of the drug is also described and its easy pediatric utilization is underlined.
