ABSTRACT
The article covers up-to-date information about the incidence of psychosomatic pathology among patients of gastroenterologic profile including patients with gastroesophageal reflux disease and syndrome of irritable colon. From the point of view of psychosomatic idea the article considers the factors predisposing, permitting and retarding the development of the disease. A detailed description is available in psychosomatic disturbances, modern concepts about their pathogenesis including a break of correlation between limbic and frontal regions of central nervous system and disorder in serotonin metabolism--clinical manifestations, methods of diagnosis and treatment including selective inhibitors and stimulators of serotonin reuptake and neuroleptics.