[Galectin-3 in differential diagnosis and prognosis of follicular tumors of the thyroid gland]. / Galektin-3 v differentsial'noi diagnostike i prognozirovanii follikuliarnykh opukholei shchitovidnoi zhelezy.

Differential diagnosis between follicular thyroid tumours (FTT) is difficult both at cytological and histological levels. Infiltrative growth is authentic criterion of malignancy. Immunohistochemical reaction (PAP-method) with galectin-3 antibodies was used. The results allow to make differential diagnosis of thyroid tumours before the surgery. Immunohistochemical identification of galectin-3 in the tissue of follicular adenomas with grave dysplasia and follicular carcinoma is an unfavourable prognostic sign.